Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: New Frontiers in Angiogenesis and Endothelial Cell Physiology
7:40 pm - 7:45 pm
Opening Remarks
7:45 pm - 8:10 pm
"Exploring Muscle Development, Disease and Regeneration"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Reprogramming the Tumor Microenvironment to Enhance Cancer Treatment: Bench to Bedside"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Signaling Pathways and Networks
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Overcoming TEKnical Challenges on the Road to New Vascular Therapies"
9:30 am - 9:40 am
Discussion
9:40 am - 9:50 am
"The Tyrosine Kinase Receptor Tie1 Shapes Different Organo-Specific Wnt Codes"
9:50 am - 9:55 am
Discussion
9:55 am - 10:15 am
"Organotypic Regulation of the Vascular Barrier"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"Designer Adaptable Endothelium to Decipher Vascular Heterogeneity"
11:15 am - 11:25 am
Discussion
11:25 am - 11:35 am
"CDS2 Deficiency Converts Outcome of VEGFa Signaling from Angiogenesis to Vascular Regression"
11:35 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"Eavesdropping Cardiovascular Regulation at Single Cell Level"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Developmental Fate, Plasticity and Differentiation
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Angiocrine Signals and Epithelial Mesenchymal Transition"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"Coronary Revascularization After Injury Is Regulated by Endocardial and Epicardial Cues and Forms a Scaffold for Cardiomyocyte Regeneration"
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:45 pm
"Novel Mechanisms Regulating Early Vascular Development"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
"Was Controls Cell Migration During Vascular Remodeling"
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:25 pm
"Investigating the Embryonic Origins of Endothelial Heterogeneity"
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Vascular Control of Organ Function
9:00 am - 9:15 am
Introduction by Discussion Leader
9:15 am - 9:35 am
"Mechanisms of Vascular Specialization in Lymph Node and Intestine"
9:35 am - 9:45 am
Discussion
9:45 am - 10:05 am
"Hepatic Angiodiversity: Vascular Control of Liver Function and Disease"
10:05 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Molecular Determinants of Intrahepatic Vascular Zonation"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Guidance of Vascular Barrier Formation"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Activating NO-sGC Pathway in Pericytes Ameliorates Inflammation-Induced Lung Injury"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Vascular Control of Oligodendrocyte Precursor Specification"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Angiocrine Metabolic Signaling Controls Muscle Regeneration by Instructing Macrophage Functional Polarization"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Remodeling of the Aging Vasculature
7:30 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:05 pm
"Cellular Heterogeneity and Plasticity in Vascular Growth"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Vascular Cell Heterogeneity and Disease"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Role of Circadian Clock Gene in Retinal Vascular Remodeling"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Building Resilience in the Vascular Wall"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Differentiation and Functions of Organotypic Vasculatures
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"The Heterogenous Origin of Endothelial Cells in Blood and Lymphatic Vasculature"
9:30 am - 9:40 am
Discussion
9:40 am - 9:50 am
"Kidney Organoids as a Dual Model of Vascular Regression and Angiocrine Signaling"
9:50 am - 9:55 am
Discussion
9:55 am - 10:15 am
"Endothelial Cells in Adipose Tissue"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:15 am
"How Chromatin-Remodeling Enzymes Reveal Insights into Organ-Specific Vascular Development and Maintenance"
11:15 am - 11:25 am
Discussion
11:25 am - 11:35 am
"DNA Methylation of a Non-Coding RNA Cluster and Endothelial Cell Fates"
11:35 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"Mechanically Induced Angiocrine Signals"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Novel Technological Developments to Study Vascular Morphogenesis
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Genetic Targeting of Organ Specific Vessels"
8:00 pm - 8:05 pm
Discussion
8:05 pm - 8:15 pm
"EXC-4/CLIC Proteins Are Ancient Regulators of Rho-Family GTPase Signaling in Tubulogenesis and Angiogenesis"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:40 pm
"Using Multispectral Genetic Mosaics to Enlighten Vascular Cell Heterogeneity"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Regulatory Pathways Governing Coronary Vessel Development Are Dysregulated After Myocardial Infarction in the Adult Heart"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Transcriptional Basis of How S1P Regulates Primary Vascular Network Formation"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Systems Biology Approaches Towards Angiogenesis and Vascular Differentiation
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Angiogenesis Revisited: The Role and (Therapeutic) Implications of Endothelial Metabolism"
9:30 am - 9:40 am
Discussion
9:40 am - 9:50 am
"Control of Endothelial Quiescence by FOXO Regulated Metabolites"
9:50 am - 9:55 am
Discussion
9:55 am - 10:15 am
"N-Glycome Regulation Limits the Endothelial Transition to Hematopoietic Stem Cells"
10:15 am - 10:25 am
Discussion
10:25 am - 11:00 am
Coffee Break
11:00 am - 11:10 am
"TGFβ Signaling in Vascular Development"
11:10 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Transcription Networks Regulating Endothelial Lineage and Function"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Low PI3-Kinase Signaling Permits Pericyte Maturation During Angiogenesis"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Hemodynamic Regulation of Valve Development and Function"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Angiogenesis in Disease and Vascular Targeted Therapies
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Organotypic Angiocrine Signatures in Aging Tissue Compartments"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Anti-Angiogenic Immunotherapy"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
"Temporal Multi-Omics Identifies LRG1 as Vascular Niche Instructor of Early Metastatic Colonization"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:15 pm
"New Insights into the Functional Role of Organ Specific Vasculature and Cell Specific Tumor Stroma in Cancer Progression and Metastasis"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
Closing Remarks
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure