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Antibody Biology and Engineering (GRS)

Gordon Research Seminar

Design and Applications of Next-Generation Antibody Technologies and Therapies

March 12 - 13, 2022

Chairs Alicia M. Chenoweth and Stuart Ainsworth

Contact Chairs

Ventura Beach Marriott

2055 Harbor Boulevard

Ventura, CA, United States

Venue and Travel Information

Conference Description

The Gordon Research Seminar on Antibody Biology and Engineering is a forum for early career researchers (ECRs, graduate students, postdocs, and scientists with comparable levels of experience and education) to present, exchange ideas, and develop collaborative networks in both academia and industry. It further provides opportunities for ECRs to meet, discuss ideas with, and receive career advice from a small group of prominent, field-leading scientists in an informal and friendly atmosphere.

The theme of the 2022 Antibody Biology and Engineering GRS is on the application of state of the art or emerging technologies and techniques which are being utilized to further antibody biology knowledge and develop novel antibody therapeutics for human and veterinary diseases. The seminar will combine many aspects of antibody research, including basic antibody biology, structure, function and diversity, with a focus on methodology and techniques with a view to generate cross-disciplinary ideas and foster potential early career researcher collaboration.

Related Meeting

This GRS will be held in conjunction with the "Antibody Biology and Engineering" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
1:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm	Keynote Session: Genetic Engineering for In Vivo Launched Biologics for EID and Pathogenic Cells Discussion Leader: Jonathan Sockolosky (Genentech Inc, United States)
3:45 pm - 4:20 pm	Trevor Smith (Inovio, United States) "Genetic Engineering for In Vivo Launched Biologics for EID and Pathogenic Cells"
4:20 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Next-Generation Antibody Technologies Discussion Leader: Taia Wang (Stanford University, United States)
7:30 pm - 7:50 pm	Monica Fernandez-Quintero (University of Innsbruck, Austria) "Antibody Structure Prediction and Docking Improved by Paratope Ensembles in Solution"
7:50 pm - 8:00 pm	Discussion
8:00 pm - 8:20 pm	Yu Gu (Univerisity of Rochester, United States) "Developing MOrPH-Antibody Fusions (‘Cyclopeptibodies’) as a New Class of Protein-Targeting Agents"
8:20 pm - 8:30 pm	Discussion
8:30 pm - 8:50 pm	David Philpott (University of Toronto, Canada) "µCellect - Next-Generation On-Cell Antibody Selection Using High-Throughput Microfluidics and Machine Learning"
8:50 pm - 9:00 pm	Discussion
9:00 pm - 9:20 pm	Tomasz Slezak (University of Chicago, United States) "A Novel Plug-and-Play Fab-Protein G Pair Platform with Multifunctional Capability"
9:20 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Antibodies in Pathology and Therapy Discussion Leader: Pierre Bruhns (Institut Pasteur, France)
9:00 am - 9:20 am	Joshua Morse (UT Health Science Center at Houston, United States) "Fc Gamma Receptor Promotion of Antibody-Induced LILRB4 Internalization and Immune Regulation of Acute Monocytic Leukemia"
9:20 am - 9:30 am	Discussion
9:30 am - 9:50 am	Lawrence Wang (NIH/Vaccine Research Center, United States) "Protective Effects of Combining Monoclonal Antibodies and Vaccines Against the Plasmodium Falciparum Circumsporozoite Protein"
9:50 am - 10:00 am	Discussion
10:00 am - 10:20 am	Ligal Aizik (Tel Aviv University, Israel) "Antibody Repertoire Analysis of Tumor-Infiltrating B Cells Reveals Distinct Signatures and Distributions Across Tissues"
10:20 am - 10:30 am	Discussion
10:30 am - 10:50 am	Jessica Stark (Stanford University, United States) "Antibody-Lectin Bispecifics for Glyco-Immune Checkpoint Blockade"
10:50 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Promoting Yourself in Academia and Industry: How to Stand Out from the Crowd Discussion Leader: Trevor Smith (Inovio, United States)
1:30 pm - 2:30 pm	Panel Discussion Promoting Yourself in Academia and Industry: How to Stand Out from the Crowd Jeanette Leusen (University Medical Center Utrecht, The Netherlands) Janine Schuurman (Genmab, The Netherlands) Laura Walker (Adimab, United States) Jonathan Sockolosky (Genentech Inc, United States)
2:30 pm - 3:00 pm	Evaluation Period Fill in GRS Evaluation Forms
3:00 pm	Seminar Concludes

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Conference History Antibody Biology and Engineering

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