1:30 pm - 4:30 pm
Arrival and Check-in
3:00 pm - 3:15 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:15 pm - 4:00 pm
Keynote Session: Dysregulation of Antimicrobial Peptides in Chronic Inflammatory Lung Disease
Pieter S. Hiemstra is professor in Respiratory Cell Biology and Immunology, and heads the Laboratory for Respiratory Cell Biology and Immunology of the Department of Pulmonology at the Leiden University Medical Center (LUMC). His research on antimicrobial peptides and proteins includes regulation of their expression as well as characterization of their functions in the context of (chronic) lung disease.
Hadeesha Piyadasa (University of Manitoba, Canada)
3:15 pm - 3:45 pm
Pieter Hiemstra (Leiden University Medical Center, The Netherlands) "Dysregulation of Antimicrobial Peptides in Chronic Inflammatory Lung Disease"
3:45 pm - 4:00 pm
4:00 pm - 5:30 pm
5:30 pm - 7:30 pm
Biological Roles of Antimicrobial Host Defense Peptides
Anthony Altieri (University of Manitoba, Canada)
5:30 pm - 5:50 pm
Nikhil Kulkarni (University of California, San Diego, USA) "Innate Immune Vetting: Cathelicidin Promotes Endothelial Dysfunction upon Cutaneous UV Injury as Seen in Rosacea Patients"
5:50 pm - 6:00 pm
6:00 pm - 6:20 pm
Maria Elena Candela (Queens Medical Research Institute, University of Edinburgh, United Kingdom) "Influence of β-Defensin on Macrophages Polarization"
6:20 pm - 6:30 pm
6:30 pm - 6:50 pm
Jessica Shartouny (Emory University, USA) "Harnessing a Frog-Derived Peptide as an Anti-Influenza Agent"
6:50 pm - 7:00 pm
7:00 pm - 7:20 pm
Mark Hanson (École Polytechnique Fédéral de Lausanne, Switzerland) "Synergy and Remarkable Specificity of Antimicrobial Peptides
In Vivo Using a Systematic Knockout Approach"
7:20 pm - 7:30 pm
8:00 pm - 9:00 pm
7:30 am - 8:30 am
9:00 am - 11:00 am
Antimicrobial Host Defense Peptide Design and Functional Characterization for Therapeutics Applications
Jessie Adams (University of South Florida, USA)
9:00 am - 9:20 am
Jessica Gilbertie (North Carolina State University, USA) "An Antimicrobial Peptide-Rich Platelet-Derived Biologic Exhibits Anti-Biofilm, Anti-Inflammatory and Chondroprotective Properties in an Equine Infectious Arthritis Model"
9:20 am - 9:30 am
9:30 am - 9:50 am
Renee Fleeman (The University of Texas at Austin, USA) "Defining the Importance of Peptide Hydrophobicity and Positive Charge for Antibacterial and Immunomodulatory Activities"
9:50 am - 10:00 am
10:00 am - 10:20 am
Martijn Riool (Academic Medical Center, University of Amsterdam, The Netherlands) "TC19, a Novel Thrombocidin-1-Derived Antimicrobial Peptide, Eradicates Multi-Drug Resistant
Staphylococcus aureus as Well as Acinetobacter baumannii in Experimental Acute Skin Infection"
10:20 am - 10:30 am
10:30 am - 10:50 am
Rida Mourtada (Dana-Farber Cancer Institute, USA) "Development of Membrane-Selective Stapled Antimicrobial Peptides to Combat Multidrug Resistant Gram-Negative Pathogens"
10:50 am - 11:00 am
11:00 am - 12:30 pm
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
1:30 pm - 2:30 pm
Mentorship Component: Opportunities and Challenges in Academic Science
Julia Dorin is professor at the University of Edinburgh and holds a chair in Genetics and Host Defence. Her research on the in vitro and in vivo functions of beta-defensins touches many topics, including the role of these defensins in the protection against infections, immune modulation and fertility. In this mentorship session, she will draw from her extensive experience to address the opportunities and challenges for young scientists within academic science.
Maarten Coorens (Karolinska Institutet, Sweden)
1:30 pm - 2:10 pm
Julia Dorin (University of Edinburgh, United Kingdom) "Opportunities and Challenges in Academic Science"
2:10 pm - 2:30 pm
2:30 pm - 3:00 pm
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