Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Human Factors and Behavior Drive the Interaction Between Patient and Device
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:05 pm
"The Unmeasured Psychological Impact of Durable MCS on the Patient and Family"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
"Enhancing the Patient Experience with Durable MCS at Home and With Providers"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
"Device Usability Engineering Considerations to Advance MCS in Younger and Older Patients"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Optimizing Healthcare Team Decision-making for Equity"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Contemporary Practices in Selection of Patients for MCS Leaves Undertreated Populations
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:25 am
"Engineering MCS Devices to Address Different Heart Sizes and Heart Anatomy"
9:25 am - 9:35 am
Discussion
9:35 am - 9:50 am
"Mechanical Circulatory Support Device for Heart Failure with Preserved Ejection Fraction (HFpEF) - Learnings from Concept to Startup"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Using a Collaborative Network for Device Trials and Expanded Labeling in Pediatrics"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:10 am
"Leveraging Unpublished Insights from the ACTION Network to Advance Clinical Decision-Making in Pediatric Mechanical Circulatory Support"
11:10 am - 11:20 am
Discussion
11:20 am - 11:35 am
"The Current and ‘Relentless’ Future Need for Durable VAD in ACHD Patients: An Exploration of Numbers and Unique Physiologies"
11:35 am - 11:45 am
Discussion
11:45 am - 12:00 pm
"Design Features of a MCS Device Utilized for a Bridge to Recovery Strategy That Will Enhance the Propensity for Recovery and lead to Greater Adoption of the Strategy"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Computer Learning and Simulation to Improve Patient Selection, Patient Management and Device Design and Development
6:00 pm - 6:15 pm
"Outcomes Following Durable MCS Therapies Are Improved by Prognostic Models Utilizing AI Algorithms"
6:15 pm - 6:25 pm
Discussion
6:25 pm - 6:40 pm
"Modeling the Use of Durable MCS to Promote Long Term Survival and Optimal Heart Donor Organ Utilization"
6:40 pm - 6:50 pm
Discussion
6:50 pm - 7:05 pm
"Innovative Approaches to Improve Hemocompatibility in MCS Devices"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:30 pm
"Machine Learning for Assisted Circulation: Haemodynamics and Device Design"
7:30 pm - 7:40 pm
Discussion
7:40 pm - 7:55 pm
"The Increasing Importance of Cybersecurity to Ensure Patient Safety"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
New Technology Blurs the Line Between the Designation of Short Term and Long Term MCS Strategies
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:25 am
"Renal Perfusion Enhancement for Decongestion in Decompensated Heart Failure"
9:25 am - 9:35 am
Discussion
9:35 am - 9:50 am
"Design Hurdles And Features Of A Counter-Pulsation MCS Device Suitable For Patient Ambulation"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Impella Outcomes in Children"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:10 am
"Potentials and Obstacles of Patient Monitoring and Physiologic Control"
11:10 am - 11:20 am
Discussion
11:20 am - 11:35 am
"Dynamic Modulation of Device-Arterial Coupling to Determine Cardiac Output and Vascular Resistance"
11:35 am - 11:45 am
Discussion
11:45 am - 12:00 pm
"Dynamic Load Modulation Predicts Right Heart Tolerance to Left Ventricular Cardiovascular Assist"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Novel Concepts Applied to the Hemodynamic Evaluation and Treatment of Right Heart Failure
6:00 pm - 6:05 pm
Introduction by Discussion Leader
6:05 pm - 6:20 pm
"Advanced Hemodynamics, Right Ventricular Optimization and Hemodynamic Related Events in LVAD Recipients: The Next Frontier of Durable Support"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
"Rotary Blood Pump Features May Expand the Role of Total Artificial Heart Therapy"
6:45 pm - 6:55 pm
Discussion
6:55 pm - 7:10 pm
"Interactions of the Ventricular Septum During Left Ventricular Unloading"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:35 pm
"Distinguishing Right Heart Failure Phenotypes to Determine If, When and How Durable MCS Should be Applied"
7:35 pm - 7:45 pm
Discussion
7:45 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Recovery and Remission to Enhance the Utilization of MCS Therapy
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:25 am
"Recovery From Advanced HF: Candidate Selection, Durability and Magnitude of Opportunity"
9:25 am - 9:35 am
Discussion
9:35 am - 9:50 am
"Defining the Phenotype of Myocardial Recovery though Proteomics: Novel Biological Patterns"
9:50 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Therapeutic Targeting of RUNX1 in Cardiac Recovery"
10:15 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:10 am
"Novel Pump Designs Based Upon the Venturi Effect"
11:10 am - 11:20 am
Discussion
11:20 am - 11:35 am
"Recoupling or Recovery: Right Ventricular Function after LVAD with Persistent Pulmonary Hypertension"
11:35 am - 11:45 am
Discussion
11:45 am - 12:00 pm
"Innovative Surgical Techniques for Faster Post-operative Recovery"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Clinical and Pre-Clinical Evaluation of Short Term and Long Term MCS Devices Has Evolved
6:00 pm - 6:05 pm
Introduction by Discussion Leader
6:05 pm - 6:20 pm
"Industry Perspectives on Contemporary Clinical Trial Designs for MCS Devices for Acute and Long-Term Applications"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:45 pm
"Feasibility of Addressing the Less-Ill Heart Failure Population with a Clinical Trial of MCS Device Versus Optimal Medical Management"
6:45 pm - 6:55 pm
Discussion
6:55 pm - 7:10 pm
"Advancing the Preclinical Hemocompatibility Evaluation of Rotodynamic Blood Pumps"
7:10 pm - 7:20 pm
Discussion
7:20 pm - 7:35 pm
"Mapping Temporary MCS Trajectories to Outcomes in Impella 5.5 Patients"
7:35 pm - 7:45 pm
Discussion
7:45 pm - 8:00 pm
General Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Mechanical Circulatory Support Devices Impact Hemodynamics and Vascular Biology
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:20 am
"Hemodynamics during VA-ECMO: Time for a Re-Think"
9:20 am - 9:30 am
Discussion
9:30 am - 9:45 am
"Hemi-ECMO: A Novel Method of Left Ventricular Afterload Reduction for Venoarterial Extracorporeal Membrane Oxygenation (VA-ECMO)"
9:45 am - 9:55 am
Discussion
9:55 am - 10:10 am
"Ventricular and Vascular Biomechanics of Veno-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO)"
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:05 am
"Microvascular Alterations During Continuous Flow Mechanical Circulatory Support"
11:05 am - 11:15 am
Discussion
11:15 am - 11:30 am
"LES as Validation Benchmark for RANS Models in Blood Pumps and the Implication of Non-Rotatory Impeller Motion"
11:30 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"Xenotransplantation, Allotransplantation, Cellular Regeneration, Medical Therapy: Can Durable MCS Stand Up to the Challenge"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Early Evaluation of Novel Device Designs
6:00 pm - 6:05 pm
Introduction by Discussion Leader
6:05 pm - 6:15 pm
"Optimization of Circulatory Support Algorithms for the TORVAD"
6:15 pm - 6:20 pm
Discussion
6:20 pm - 6:30 pm
"The BrioVAD Experience: Device Design, Clinical Trial Design, and Clinical Update"
6:30 pm - 6:35 pm
Discussion
6:35 pm - 6:45 pm
"CorWave LVAD - Pulsatile, Self-Adaptive Wave Membrane Technology"
6:45 pm - 6:50 pm
Discussion
6:50 pm - 7:00 pm
"Mi-VAD: A Novel Intra-Vascular Cardiac Assist Device; Moving Away from the Apical Cannulation Paradigm"
7:00 pm - 7:05 pm
Discussion
7:05 pm - 7:25 pm
"Focusing and Prioritizing the Development of Durable MCS Device Technology."
7:25 pm - 7:35 pm
Discussion
7:35 pm - 7:55 pm
General Discussion
7:55 pm - 8:00 pm
Closing Remarks
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure