Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Attention, Prospects and Lessons for the Auditory System
7:40 pm - 7:45 pm
Introduction by Discussion Leader
7:45 pm - 8:10 pm
"Cochlear Synaptopathy in Acquired Sensorineural Hearing Loss: Research Progress and Therapeutic Prospects"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:45 pm
"Control of Spatial and Non-Spatial Auditory Attention"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Retinal Gene Therapy and Lessons for the Auditory System"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Building and Rebuilding Auditory Transduction
9:00 am - 9:20 am
"The MET Complex in Zebrafish"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"The Tectorial Membrane, a Matrix Required for Normal Hearing: Effects of Mutations and Ageing"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Contributions of Internally Coupled Ears to Localization and Auditory Sensitivity Reduction in Frogs"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:10 am
"Structural Features of the Hair-Cell Transduction Channel"
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
"Identification of the Pore Region of TMC1 Using Cysteine Mutagenesis"
11:25 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Optogenetic Restoration of Hearing"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Old Gene, New Phenotype: Splice-Altering Variants in CEACAM16 Cause Recessive Non-Syndromic Hearing Impairment"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Genetics of Auditory Function and Dysfunction
7:30 pm - 7:50 pm
"Diversification of Type I Spiral Ganglion Neurons by IHC-Driven Activity"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Epigenetic Mechanisms Governing Development and Failure of Regeneration in the Inner Ear"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Transcriptome Profiling in the Auditory Pathway: Characterizing Genomic Change in Development, Aging and Pathology"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Hidden Cortical Deficits in Hereditary Deafness"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Physiology and Pathology of Auditory Synapses
9:00 am - 9:20 am
"Modulation of Hair Cell Afferent Transmission by Lateral Efferent Fibers"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Quantitative Analyses of Synaptic Connectivity in the Cochlear Nucleus"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Cortical Circuits for Dynamic Auditory Perception"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:10 am
"Medial Olivocochlear Neurons Receive Inhibitory Input from the Medial Nucleus of the Trapezoid Body"
11:10 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Attention and Aging in Auditory Thalamus: Cholinergic Transmission and Predictive Coding"
11:35 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Cortical Circuits Underlying Audition"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Unique Connections in the Auditory Pathways
7:30 pm - 7:50 pm
"Gap Junction Networks Facilitate Presynaptic Activity in Lateral-Line Hair Cells"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Cochlear Nucleus Connectome: A Platform to Study the Mammalian Auditory System"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"The Eardrum Moves When the Eyes Move: A Multisensory Effect on the Mechanics of Hearing"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Cortical Mechanisms Supporting Complex Sound Processing"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Auditory Plasticity Following Auditory Pathology
9:00 am - 9:20 am
"Plasticity of Intrinsic Circuits in the Inferior Colliculus"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"A Cortical Filter Learns and Suppresses the Acoustic Consequences of Movement"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Plasticity in Auditory Cortex Following Hearing Loss"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Inhibitory Circuit Gating of Auditory Cortical Plasticity"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Attention-Driven Transformations in Auditory Processing"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Neuromodulation and Plasticity for a Rodent Model of Cochlear Implant Use"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Novel Approaches for Investigating the Auditory System
7:30 pm - 7:50 pm
"Chicken Inner Ear Hair Cell Regeneration at High Temporal and Spatial Resolution"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"From Fins to Fur: Drug Development for Hearing Protection"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Identification of Novel Neuron Classes in the Inferior Colliculus"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 9:05 pm
"Examining Inner Ear Development Using Single Cell RNAseq"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"The Development of a Nonhuman Primate Model for Noise Induced Hearing Loss"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Emerging Therapies for Auditory Restoration
9:00 am - 9:20 am
"Combined Electric and Acoustic Stimulation: Mechanisms Driving Patient Benefit"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Directed Self-Assembly of Human Inner Ear Organoids"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"The Deafness Variation Database: A Deafness-Specific Comprehensive Platform for the Classification and Dissemination of Genetic Variants"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Novel Therapies for Protecting and Regenerating Sensory Cells in the Cochlear After Hearing Loss"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Next Generation Gene Therapy Restores Hearing and Balance in Mouse Models of Genetic Inner Ear Disorder"
11:40 am - 11:45 am
Discussion
11:45 am - 12:05 pm
"Major Barriers to Overcome for Translational Success of Cochlear Gene Therapy"
12:05 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Electrical Stimulation of the Dorsal Cochlear Nucleus: Effects of Dorsal Acoustic Stria Cuts"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Regulation and Dysregulation of Auditory Pathways
7:30 pm - 7:50 pm
"Zika Virus Infection During CNS and Inner Ear Development"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Axon-Glia Communication During Activity Dependent Regulation of Axonal Conduction"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Cochlear Macrophages Influence the Survival of Auditory Neurons"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Increasing Inhibitory Gain During Development Enhances Perception"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:30 pm
Closing Remarks
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure