Sunday
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2:00 pm - 9:00 pm |
Arrival and Check-in
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 7:40 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
|
7:40 pm - 9:30 pm |
Plasma Membrane Processes
Discussion Leader: Nina Salama (Fred Hutchinson Cancer Research Center, USA)
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7:40 pm - 7:45 pm |
Introduction by Discussion Leader
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7:45 pm - 8:05 pm |
Jeff Errington (Newcastle University, United Kingdom)
"L-Form Bacteria: Genetics, Cell Cycle and Recurrent Infection"
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8:05 pm - 8:15 pm |
Discussion
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8:15 pm - 8:35 pm |
Paula Welander (Stanford University, USA)
"Biosynthesis of Membrane Lipids in Sulfolobus acidocaldarius"
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8:35 pm - 8:45 pm |
Discussion
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8:45 pm - 9:05 pm |
Leonid Sazanov (Institute of Science and Technology Austria, Austria)
"Coupling Mechanism of Respiratory Complex I"
|
9:05 pm - 9:15 pm |
Discussion
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9:15 pm - 9:25 pm |
Timothy Knowles (University of Birmingham, United Kingdom)
"Rethinking the Mla Pathway: Evidence for Anterograde Lipid Trafficking"
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9:25 pm - 9:30 pm |
Discussion
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Monday
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7:30 am - 8:30 am |
Breakfast
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9:00 am - 12:30 pm |
Building the Cell Wall
Discussion Leader: Eefjan Breukink (Utrecht University, The Netherlands)
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9:00 am - 9:10 am |
Introduction by Discussion Leader
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9:10 am - 9:35 am |
Martin Loose (Institute of Science and Technology Austria, Austria)
"Self-Organization of the Bacterial Cell Division Machinery"
|
9:35 am - 9:45 am |
Discussion
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9:45 am - 10:10 am |
Mariana Pinho (Instituto de Tecnologia Quimica e Biologica, Universidade NOVA de Lisboa, Portugal)
"Coordination Between Peptidoglycan Synthesis and Cell Division"
|
10:10 am - 10:20 am |
Discussion
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10:20 am - 10:50 am |
Coffee Break
|
10:50 am - 11:15 am |
Michael Vannieuwenhze (Indiana University, USA)
"Recent Developments with Fluorescent D-Amino Acids and Their Utility in the Study of Bacterial Cell Division"
|
11:15 am - 11:25 am |
Discussion
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11:25 am - 11:50 am |
Alessandra Polissi (University of Milano, Italy)
"Peptidoglycan Remodeling Enables E. coli to Survive Severe Outer Membrane Assembly Defects"
|
11:50 am - 12:00 pm |
Discussion
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12:00 pm - 12:10 pm |
Alexander Egan (Centre for Bacterial Cell Biology, Newcastle University, United Kingdom)
"Induced Conformational Changes Activate the Bifunctional Peptidoglycan Synthase PBP1B"
|
12:10 pm - 12:15 pm |
Discussion
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12:15 pm - 12:25 pm |
Megan Sjodt (Harvard Medical School, USA)
"Structure and Function of the SEDS:bPBP Bacterial Cell Wall Synthesis Machinery"
|
12:25 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Cell Division and Morphogenesis
Discussion Leader: Tanneke Den Blaauwen (University of Amsterdam, The Netherlands)
|
7:30 pm - 7:35 pm |
Introduction by Discussion Leader
|
7:35 pm - 7:55 pm |
Malcolm Winkler (Indiana University Bloomington, USA)
"Movement Dynamics of Proteins that Mediate and Regulate Peptidoglycan Synthesis in Cells of Streptococcus pneumoniae"
|
7:55 pm - 8:05 pm |
Discussion
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8:05 pm - 8:30 pm |
Hesper Rego (Yale University, USA)
"Asymmetry and Heterogeneity in Mycobacterial Growth and Division"
|
8:30 pm - 8:40 pm |
Discussion
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8:40 pm - 9:05 pm |
Zemer Gitai (Princeton University, USA)
"Bacterial Shape and Cytoskeletal Regulation"
|
9:05 pm - 9:15 pm |
Discussion
|
9:15 pm - 9:25 pm |
Riti Mann (University of Technology Sydney, Australia)
"We Are What We Eat: Identifying a Regulatory Crosstalk Between Central Carbon Metabolism and Cell Division in Bacteria"
|
9:25 pm - 9:30 pm |
Discussion
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Tuesday
|
7:30 am - 8:30 am |
Breakfast
|
8:30 am - 9:00 am |
Group Photo
|
9:00 am - 12:30 pm |
A Dynamic Cell Wall
Discussion Leader: Kerwyn Huang (Stanford University, USA)
|
9:00 am - 9:10 am |
Introduction by Discussion Leader
|
9:10 am - 9:35 am |
Ethan Garner (Harvard University, USA)
"New Feedback Loops Controlling Cell Width and Growth"
|
9:35 am - 9:45 am |
Discussion
|
9:45 am - 10:10 am |
Jan-Willem Veening (University of Lausanne, Switzerland)
"Identification of a Unique Cell Cycle Regulator in Streptococcus pneumoniae by En Masse GFP Localization, Tn-Seq and CRISPRi Phenotyping"
|
10:10 am - 10:20 am |
Discussion
|
10:20 am - 10:50 am |
Coffee Break
|
10:50 am - 11:15 am |
Tanja Schneider (University of Bonn, Germany)
"Integration of Capsule Formation into the Cell Wall Biosynthetic Network"
|
11:15 am - 11:25 am |
Discussion
|
11:25 am - 11:50 am |
Enrique Rojas (New York University, USA)
"The Mechanical Properties of the Outer Membrane"
|
11:50 am - 12:00 pm |
Discussion
|
12:00 pm - 12:10 pm |
Kelsi Sandoz (Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, NIH, USA)
"Covalent Attachment of Porins to Peptidoglycan Promotes Cell Envelope Stability in the Absence of Braun's Lipoprotein"
|
12:10 pm - 12:15 pm |
Discussion
|
12:15 pm - 12:25 pm |
Jason Peters (University of California, San Francisco, USA)
"CRISPR-Based Dissection of Bacterial Cell Wall Pathways"
|
12:25 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Outer Membrane Biogenesis and Function
Discussion Leader: Stephen Trent (University of Georgia, USA)
|
7:30 pm - 7:35 pm |
Introduction by Discussion Leader
|
7:35 pm - 7:55 pm |
Damian Ekiert (New York University School of Medicine, USA)
"Architectures of Lipid Transport Systems for the Bacterial Outer Membrane"
|
7:55 pm - 8:05 pm |
Discussion
|
8:05 pm - 8:30 pm |
Sheena Radford (University of Leeds, United Kingdom)
"Folding and Assembly of Proteins into the Outer Membrane of E. coli"
|
8:30 pm - 8:40 pm |
Discussion
|
8:40 pm - 9:05 pm |
Bert van den Berg (Newcastle University, United Kingdom)
"Nutrient Acquisition by the Human Gut Microbiota"
|
9:05 pm - 9:15 pm |
Discussion
|
9:15 pm - 9:25 pm |
Shu Sin Chng (National University of Singapore, Singapore)
"Biosynthetic Intermediates of an Exopolysaccharide Exhibit Stabilizing Effects on the Outer Membrane in Escherichia coli"
|
9:25 pm - 9:30 pm |
Discussion
|
Wednesday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am - 12:30 pm |
Cell Envelope Macromolecular Machines
Discussion Leader: Judith Armitage (University of Oxford, United Kingdom)
|
9:00 am - 9:10 am |
Introduction by Discussion Leader
|
9:10 am - 9:35 am |
Ben Luisi (University of Cambridge, United Kingdom)
"Structure and Mechanism of Bacterial Multi-Drug Efflux Pumps"
|
9:35 am - 9:45 am |
Discussion
|
9:45 am - 10:10 am |
Trevor Lithgow (Monash University, Australia)
"The Assembly of Protein Secretion Systems into the Bacterial Outer Membrane"
|
10:10 am - 10:20 am |
Discussion
|
10:20 am - 10:50 am |
Coffee Break
|
10:50 am - 11:15 am |
Jun Liu (Yale University, USA)
"In Situ Structure and Function of Bacterial Secretion Machines"
|
11:15 am - 11:25 am |
Discussion
|
11:25 am - 11:50 am |
Marek Basler (University of Basel, Switzerland)
"Bacterial Type VI Secretion System: From Structure to Dynamics and Function"
|
11:50 am - 12:00 pm |
Discussion
|
12:00 pm - 12:10 pm |
Ben Berks (University of Oxford, United Kingdom)
"Type IX Protein Secretion"
|
12:10 pm - 12:15 pm |
Discussion
|
12:15 pm - 12:25 pm |
Marcin Grabowicz (Emory University, USA)
"Chemical Biology Insights into Outer Membrane Protein Biogenesis"
|
12:25 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:00 pm - 7:30 pm |
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
|
7:30 pm - 9:30 pm |
Cell Surfaces: A Barrier and a Target for Antibacterials
Discussion Leader: Jeff Errington (Newcastle University, United Kingdom)
|
7:30 pm - 7:35 pm |
Introduction by Discussion Leader
|
7:35 pm - 7:55 pm |
Suzanne Walker (Harvard Medical School, USA)
"Regulation of Peptidoglycan Synthesis in Staphylococcus aureus"
|
7:55 pm - 8:05 pm |
Discussion
|
8:05 pm - 8:30 pm |
Jennifer Leeds (Novartis Institutes for BioMedical Research, USA)
"Discovery and Early Development of LYS228"
|
8:30 pm - 8:40 pm |
Discussion
|
8:40 pm - 9:05 pm |
Athanasios Typas (European Molecular Biology Laboratory, Germany)
"Species-Specific Activity of Drug Combinations"
|
9:05 pm - 9:15 pm |
Discussion
|
9:15 pm - 9:25 pm |
Roman Dziarski (Indiana University, USA)
"Human Peptidoglycan Recognition Proteins Kill Bacteria by Inducing Oxidative Stress Through a Block in the Respiratory Chain"
|
9:25 pm - 9:30 pm |
Discussion
|
Thursday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am - 12:30 pm |
Bacterial Communities/Microbiome
Discussion Leader: Melanie Blokesch (Swiss Federal Institute of Technology Lausanne (EPFL), Switzerland)
|
9:00 am - 9:10 am |
Introduction by Discussion Leader
|
9:10 am - 9:35 am |
Bonnie Bassler (Princeton University, USA)
"Bacterial Quorum Sensing and Its Control"
|
9:35 am - 9:45 am |
Discussion
|
9:45 am - 9:55 am |
Katarzyna Mickiewicz (Centre for Bacterial Cell Biology, Newcastle University, United Kingdom)
"L-Form Switching as a Potential Mechanism for the Recurrence of Urinary Tract Infections"
|
9:55 am - 10:00 am |
Discussion
|
10:00 am - 10:10 am |
Georgia Isom (NYU Langone Medical Center, USA)
"Deciphering a Mechanism of Lipid Transport for the Bacterial Outer Membrane"
|
10:10 am - 10:15 am |
Discussion
|
10:15 am - 10:50 am |
Coffee Break
|
10:50 am - 11:15 am |
Matt Traxler (University of California, Berkeley, USA)
"Genetic Control of Specialized Metabolism During Actinomycete Interactions"
|
11:15 am - 11:25 am |
Discussion
|
11:25 am - 11:50 am |
Andrew Goodman (Yale University, USA)
"Vitamin Capture by Human Gut Microbes"
|
11:50 am - 12:00 pm |
Discussion
|
12:00 pm - 12:10 pm |
Salim Islam (INRS-Institut Armand-Frappier Research Centre, Canada)
"Integrin-Like Tethering of Motility Complexes at Bacterial Focal Adhesions"
|
12:10 pm - 12:15 pm |
Discussion
|
12:15 pm - 12:25 pm |
Sloan Siegrist (University of Massachusetts Amherst, USA)
"Membrane Partitioning of Mycobacterial Peptidoglycan Synthesis"
|
12:25 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Cell Biology of the Envelope
Discussion Leader: Elizabeth Sockett (University of Nottingham, United Kingdom)
|
7:30 pm - 7:35 pm |
Introduction by Discussion Leader
|
7:35 pm - 7:55 pm |
Arash Komeili (University of California, Berkeley, USA)
"Lipid-Bounded Organelles in Bacteria"
|
7:55 pm - 8:05 pm |
Discussion
|
8:05 pm - 8:30 pm |
Jade Wang (University of Wisconsin-Madison, USA)
"(p)ppGpp Mediates Antibiotic Tolerance in Gram-Positive Bacteria"
|
8:30 pm - 8:40 pm |
Discussion
|
8:40 pm - 9:05 pm |
Alan Grossman (Massachusetts Institute of Technology, USA)
"Crossing Boundaries: Promiscuity and Exclusivity in Bacterial Sex"
|
9:05 pm - 9:15 pm |
Discussion
|
9:15 pm - 9:25 pm |
Yu-Ling Shih (Academia Sinica, Taiwan)
"Synchronizing Min Oscillation with Nutrient Availability in Escherichia coli"
|
9:25 pm - 9:30 pm |
Discussion
|
Friday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am |
Departure
|