Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Basal Ganglia in Motivational Control and Reward Processing
7:40 pm - 8:20 pm
"Direct and Indirect Pathways Oppositely Shift Neural Activity Along the Decision Axis"
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
"Physiology of Midbrain Dopaminergic Neuron Subpopulations"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Probing Heterogeneity in Basal Ganglia Cell Types and Subcircuits
9:00 am - 9:20 am
"Organization and Function of a Specialized Dopamine System"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Genetic Resolution of Distinct GABAergic Subpopulations of the Ventral Midbrain"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
Short Talk Selected from Poster Abstracts
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Short Talk Selected from Poster Abstracts
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Molecular Probes for Tracking Neuromodulation"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Molecular Ballet: Decoding Biochemical Signaling Dynamics in the Brain"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Spying on Neuromodulator Dynamics in vivo by Constructing Multi-Color GRAB Sensors"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Encoding and Decoding Basal Ganglia Neuronal Activity in Behavior
6:00 pm - 6:20 pm
"What's the Function of the Basal Ganglia Beyond Movement Control in Primates?"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Striatal Signaling in Action"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"The Striatum Shapes Performance Across Trained and Naturalistic Behaviors"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Thalamocortical Mediated Dendritic Reorganization in Pyramidal Tract Neurons During Motor Learning"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Motivated Behavior and Non-Motor Basal Ganglia Function
9:00 am - 9:20 am
"Sleep and Motor Control by a Basal Ganglia Circuit"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Reduced SK Channel Control of Mesolimbic Dopamine Neuron Activity in Chronic Pain"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
Short Talk Selected from Poster Abstracts
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Short Talk Selected from Poster Abstracts
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"A Synaptic Mechanism for Encoding the Learned Value of Action-Derived Safety"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Tail Striatal Neurovascular Coupling in Auditory Discrimination Learning"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Roles for Astrocytes in Basal Ganglia Plasticity and Circuit Function
6:00 pm - 6:20 pm
"Dicovering the Power of Activated Astrocyte Ensembles in the Nucleus Accumbens"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Astrocyte Regulation of Synaptic Transmission and Plasticity in the Nucleus Acccumbens"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Causal Contributions of Reactive Astrogliosis in vivo "
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Astrocyte-Neuron Interactions in the Striatum-Pallidum Circuits for Reversal Learning and Compulsive Reward-Seeking Behaviors"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
New Models for Basal Ganglia Function
9:00 am - 9:20 am
"Complementary Contributions of Ventral and Dorsal Striatum to the Effort–Time Tradeoff During Foraging"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Neural Mechanisms of a Latent Decision in the Basal Ganglia"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
Short Talk Selected from Poster Abstracts
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Short Talk Selected from Poster Abstracts
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Second-Order Win-Stay, Lose-Shift: Behavioral Evidence, Computational Modeling and Striatal Function"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Reciprocal Cerebellar-Basal Ganglia Interactions"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Basal Ganglia Circuit Logic In Vivo and Ex Vivo
6:00 pm - 6:20 pm
"Direct Excitation of the Substantia Nigra pars reticulata by Primary and Secondary Motor Cortices"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Non-Invasive Targeted Drug Delivery Using Focused Ultrasound to Characterize the Cellular Effects of Dopamine in the Striatum."
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Basal Ganglia Input to the Pedunculopontine Nucleus Modulates Locomotion and Valence"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Cell-Type-Specific Synaptic Logic in Striatal Circuits: Molecular Constraints on Adaptive Behavior"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Basal Ganglia Pathophysiology: Movement and Psychiatric Disorders
9:00 am - 9:20 am
"Aberrant Basal Ganglia Activity in a Mouse Model of Dystonia"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"The Battle Within--Spike Rate vs. Synchrony: Which Neuronal Changes Drive Parkinsonian Motor Deficits?"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
Short Talk Selected from Poster Abstracts
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Short Talk Selected from Poster Abstracts
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Breaking the Loop: Striatal Interneurons and the Regulation of Repetitive Behavior"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Serotonin Inhibits Striatal D1 Neurons to Terminate Aggressive Behavior"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Neuromodulatory Interactions in the Basal Ganglia
6:00 pm - 6:20 pm
"Adenosine Regulation of Striatal Circuits"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"Topographic Organization and Behavioral Functions of Non-Uniform DA-ACh Interactions Across the Striatum"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Serotonin Modulation of Striatal Activity Depends on Behavioral Context"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Diverse Roles for Astrocytes in Shaping Neuromodulator Interactions in the Striatum"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure