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Session I: Structure and Function of Basement Membrane Molecules and their Supramolecular Assembly
- Discussion Leaders: Peter Yurchenco and Jurgen Engel
- Jurgen Engel (Biocenter, Univ. Basel): X-ray structure of the calcium-binding domain in SPARC/osteonectin/BM40 and other extracellular calcium-binding proteins
- Lynn Sakai: (Shriner's Hospital, Portland, OR): Fibrillin and new matrix components.
- Markus Ruegg (Biocenter, Univ. Basel): The role of agrin and its binding proteins during the formation of the neuromuscular junction.
Session II: Cellular Receptors for Basement Membranes
- Discussion Leader: Caroline Damsky (U.C.S.F.)
- Arnoud Sonnenberg (Netherlands Cancer Institute): Genetic analysis of alpha6beta4 integrin function in man and mouse.
- Reinhardt Fassler (Max Planck Institute Martinsreid): Role of beta1 integrins in embryonic development.
Session III: Basement Membrane and Extracellular Matrix in Neuronal Development
- Discussion Leader: Lou Reichardt (U.C.S.F.)
- Arthur Lander (U.C. Irvine): Proteoglycans in neuronal development
- Marc Tessier-Lavigne (U.C.S.F.): Axonal Guidance by Diffusable Attractants and Repellents.
Session IV: Basement Membrane and Extracellular Matrix in Neuromuscular Development
- Discussion Leader: Eva Engvall (La Jolla Cancer Research Foundation)
- Eva Engvall: Laminins and muscular disorders.
- Joshua Sanes (Univ. Washington): The neuromuscular junction.
- Kevin Campbell (Univ. Iowa): Muscular dystrophies and basal lamina.
Session V: Genetic and Other Human Disorders of Basement Membrane
- Discussion Leader: Karl Tryggvason (Karolinska Institute, Stockholm)
- Robert Burgeson (Cutaneous Biology Research Center, Harvard): Structure and functions of epithelial laminins
- Angela Christiano (Columbia University): Disorders of the epidermal/dermal junction.
- Helen Blau (Stanford Univ. School of Med.): Regulated gene expression in development and gene therapy.
Session VI: Genetic Analysis of Basement Membrane Function - I
- Discussion Leader: Albert Chung (Univ. Pittsburgh)
- Albert Chung: In vivo function of entactin.
- Ulricke Mayer (Max Planck Institute Martinsreid): Nidogen functions in vitro and in vivo.
- Jim Kramer (Northwestern Univ. Med. Sch.): Analysis of type IV collagen function in C. elegans development.
Session VII: Genetic Analysis of Basement Membrane Function II
- Discussion Leader: Lisa Fessler (U.C.L.A.)
- Bill Wadsworth (Robert Wood Johnson Medical School): Netrin UNC-6, basement membranes, and the developing nervous system of C. elegans.
- Douglas Fambrough (U.C. Berkeley): Interactions between growth cones and their extracellular environment - a genetic analysis in Drosophila.
Keynote Speaker:
- Richard Hynes (M.I.T. Cancer Center): Genetic analysis of adhesion.
Session VIII: Basement Membranes and Extracellular Matrix in Embryonic Development
- Discussion Leader: Brigid Hogan
- Brigid Hogan: Role of bone morphogenetic proteins in mouse development.
- Seppo Vainio (Harvard Univ., Dept. of Biology): Wnt genes and kidney development.
- Eduardo Almedia (Univ. Virginia): The a6b1 integrin as a sperm receptor
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