| THURSDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | JOINT SESSION WITH METALS IN BIOLOGY |
| Discussion Leader: Harry Gray (California Institute of Technology) |
| Introduction: Alison Butler (University of California, Santa Barbara) |
| George McLendon (Princeton University)
"Cytochrome c and the Suicide Hot Line" |
| 9:30 pm - | Poster Session (Presented by GRS) |
| FRIDAY |
| 8:30 am | Conference Photo |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | ENVIRONMENTAL BIOINORGANIC CHEMISTRY |
| Discussion Leader: Alison Butler (University of California, Santa Barbara) |
| 9:15 am - 9:45 am | Jana Lewis (University of California, San Diego)
"Characterization of Novel Lead Chelators" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:20 am | Greg Dick (Scripps Institution of Oceanography)
“Determining the role of multicopper oxidases in manganese oxidation by marine Bacillus spores” |
| 10:20 am - 10:25 am | Discussion |
| 10:25 am - 10:45 am | Coffee Break |
| 10:45 am - 11:15 am | Mary Sever (Purdue University)
“Metal-Induced Protein Cross-Linking in Marine Biomaterial Formation” |
| 11:15 am - 11:20 am | Discussion |
| 11:20 am - 11:50 am | Gary Icopini (Los Alamos National Laboratory)
"Actinide trace element biogeochemistry related to iron and manganese cycles" |
| 11:50 am - 11:55 am | Discussion |
| 11:55 am - 12:25 pm | Raquel Lieberman (Northwestern University)
"Biophysical characterization of particulate methane monooxygenase" |
| 12:25 pm- 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 5:00 pm - 6:00 pm | Workshop and Discussion
Bioinorganic Chemistry in Industry
Bahram Moasser (GE Global Research Center) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | METALLONEUROCHEMISTRY and METALS IN MEDICINE |
| Discussion Leader: Hilary Godwin (Northwestern University) |
| 7:45 pm - 8:15 pm | S. Brooke Shields (University of Iowa) "De Novo Designed Copper-Binding
Peptides: Investigation of the Prion Protein's Octarepeat Motif in a
New Context" |
| 8:15 pm - 8:20 pm | Discussion |
| 8:20 pm - 8:50 pm | Ok-Ho Shin (University of Texas Southwestern Medical Center, Dallas) "Synaptotagmin" |
| 8:50 pm - 8:55 pm | Discussion |
| 8:55 pm - 9:25 pm | Juewen Liu (University of Illinois at Urbana-Champaign) "Design of fluorescent and colorimetric biosensors based on a new metallo-DNAzyme" |
| 9:25 pm - 9:30 pm | Discussion |
| SATURDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | BIOINORGANIC REACTION MECHANISMS |
| Discussion Leader: Larry Que (University of Minnesota) |
| 9:15 am - 9:45 am | Dorothee Lahaye (Princeton University)
"Cationic Oxomanganese Porphyrins: Formation and Reactivity" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:20 am | Wendy Belliston Bittner (California Institute of Technology)
"Probing the Active Site and Mechanism of Inducible Nitric Oxide Synthase" |
| 10:20 am - 10:25 am | Discussion |
| 10:25 am - 10:45 am | Coffee Break |
| 10:45 am - 11:15 am | Michael Bukowski (University of Minnesota)
"Factors influencing the formation of synthetic nonheme iron(IV)-oxo species" |
| 11:15 am - 11:20 am | Discussion |
| 11:20 am - 11:50 am | Brian Kail (Duquesne University)
"The Oxygen Atom Transfer Reaction of a [MoO2]2+ Core That Proceeds via an Isolatable Reaction Intermediate" |
| 11:50 am - 11:55 am | Discussion |
| 11:55 am - 12:25 pm | Anne Reynolds (University of Minnesota)
"Synthetic Modeling of Dioxygen Activation by Mononuclear Copper Enzymes" |
| 12:25 pm- 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | METALS, PROTEINS, AND NUCLEIC ACIDS |
| Discussion Leader: Joan Broderick (Michigan State University) |
| 7:45 pm - 8:15 pm | Yuming Xiao (University of California, Davis)
"Nuclear Resonant Vibration Spectroscopy (NRVS) and Normal Mode Analysis of Rubredoxin" |
| 8:15 pm - 8:20 pm | Discussion |
| 8:20 pm - 8:50 pm | Lionel Cheruzel (University of Louisville)
"Enzyme active site modeling studies using novel amide functionalized imidazole ligands" |
| 8:50 pm - 8:55 pm | Discussion |
| 8:55 pm - 9:25 pm | Leticia Llarrull (Universidad Nacional de Rosario)
"Depicting the catalytic mechanism of the metallo-b-lactamase of B.cereus" |
| 9:25 pm - 9:30 pm | Discussion |
| 9:30 pm - 10:00 pm | Business Meeting |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | METAL ION TRANSPORT AND HOMEOSTASIS |
| Discussion Leader: Al Crumbliss (Duke University) |
| 9:15 am - 9:45 am | Lydia Finney (Northwestern University)
"The chemical secrets of metal trafficking proteins" |
| 9:45 am - 9:50 am | Discussion |
| 9:50 am - 10:20 am | Christopher Stoj (University at Buffalo)
"Cuprous oxidase activity of yeast Fet3p and human ceruloplasmin: implication for function" |
| 10:20 am - 10:25 am | Discussion |
| 10:25 am - 10:45 am | Coffee Break |
| 10:45 am - 11:15 am | Peter Bryngelson (University of Massachusetts, Amherst) "A molecular biological and spectroscopic investigation of NiSOD" |
| 11:15 am - 11:20 am | Discussion |
| 11:20 am - 11:50 am | Xiaofeng Liu (Children's Hospital Oakland Research Institute) "Ferritin activities: Iron in and iron out" |
| 11:50 am - 11:55 am | Discussion |
| 11:55 am - 12:25 pm | Liliana Quintanar (Stanford University)
"Ferrous binding to the multicopper oxidases S. cerevisiae Fet3p and human ceruloplasmin" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch and Departure |