Thursday 
 
 
4:00 pm - 8:00 pm 
	
Arrival and Check-in
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
New Free Radical and Organometallic Enzyme Chemistry 
 
 
 
						
7:30 pm - 7:50 pm 
	
"Fe4 S4  Clusters Featuring a Reactive Fe Site: Preparation of Alkyl Complexes Relevant to Radical-SAM Enzymes" 
 
 
 
						
7:50 pm - 8:00 pm 
	
Discussion
 
 
						
8:00 pm - 8:20 pm 
	
"From Interferon-Stimulated to a New Antiviral: The Story of Viperin" 
 
 
 
						
8:20 pm - 8:30 pm 
	
Discussion
 
 
						
8:30 pm - 9:15 pm 
	
"New Insight into Cobalamin-Dependent Methylation" 
 
 
 
						
9:15 pm - 9:30 pm 
	
Discussion
 
 
						
9:30 pm - 11:00 pm 
	
Poster Session 
Joint Poster Session with the Metals in Biology GRC 
 
 
						
	Friday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
8:30 am - 9:00 am 
	
Group Photo
 
 
						
9:00 am - 12:30 pm 
	
Using the Bioinorganic Toolbox: New Methods and Techniques to Understand the Role of Metals in Nature 
 
 
 
						
9:00 am - 9:20 am 
	
"Electrochemical Hydrogen Evolution Catalyzed by CoMP11-Ac: Who Is the Substrate?" 
 
 
 
						
9:20 am - 9:30 am 
	
Discussion
 
 
						
9:30 am - 9:50 am 
	
"Structural Basis for Superoxide Activation of Class Id Ribonucleotide Reductases" 
 
 
 
						
9:50 am - 10:00 am 
	
Discussion
 
 
						
10:00 am - 10:20 am 
	
"Determining the Effects of Heme Pocket Residues on the Signal Transduction Within Globin Coupled Sensors" 
 
 
 
						
10:20 am - 10:30 am 
	
Discussion
 
 
						
10:30 am - 11:00 am 
	
Coffee Break
 
 
						
11:00 am - 11:20 am 
	
"Biological Methane Oxidation Is Catalyzed by a Mononuclear Copper Center" 
 
 
 
						
11:20 am - 11:30 am 
	
Discussion
 
 
						
11:30 am - 11:50 am 
	
"The Curious Case of Reverbβ: Chemical Reaction Coupling of Electron Transfer Makes Ferric Heme a Gas Sensor" 
 
 
 
						
11:50 am - 12:00 pm 
	
Discussion
 
 
						
12:00 pm - 12:20 pm 
	
"Substrate Analogue Reactivity in HydG: Radical Counterparts of Relevant Intermediates" 
 
 
 
						
12:20 pm - 12:30 pm 
	
Discussion
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
Applications of Metals in Biology: Biological Materials, Biomineralization, Therapeutics and Imaging 
 
 
 
						
7:30 pm - 7:45 pm 
	
"Repeat Proteins as Versatile Scaffolds for Arrays of Redox-Active Fe-S Clusters" 
 
 
 
						
7:45 pm - 7:50 pm 
	
Discussion
 
 
						
7:50 pm - 8:05 pm 
	
"Designed Artificial Iron Proteins" 
 
 
 
						
8:05 pm - 8:10 pm 
	
Discussion
 
 
						
8:10 pm - 8:25 pm 
	
"Enzyme-Catalyzed CdSe Quantum Dot Growth and Functionalization" 
 
 
 
						
8:25 pm - 8:30 pm 
	
Discussion
 
 
						
8:30 pm - 8:45 pm 
	
"Chemoselective Cyclopropanation over Carbene Y-H Insertion Catalyzed by an Engineered Carbene Transferase" 
 
 
 
						
8:45 pm - 8:50 pm 
	
Discussion
 
 
						
8:50 pm - 9:05 pm 
	
"Spin Dynamics of Coordination Complexes and Materials as Model Systems for Biology" 
 
 
 
						
9:05 pm - 9:10 pm 
	
Discussion
 
 
						
9:10 pm - 9:25 pm 
	
"Repurposing Cytochrome P450s for Selective C(sp3)-H Perfluoroalkylation Using Directed Evolution" 
 
 
 
						
9:25 pm - 9:30 pm 
	
Discussion
 
 
						
	Saturday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 12:30 pm 
	
Inspired by Nature: Understanding the Role of Metals and Structure-Function Relationships in Catalysis 
 
 
 
						
9:00 am - 9:20 am 
	
"A Four-Coordinate {CuNO}10 by Nitrite Reduction and Implications for Oxidative Stress" 
 
 
 
						
9:20 am - 9:30 am 
	
Discussion
 
 
						
9:30 am - 9:50 am 
	
"Utilizing Metal Reducing Enzymes as Tags in Optical and Electron Microscopy" 
 
 
 
						
9:50 am - 10:00 am 
	
Discussion
 
 
						
10:00 am - 10:20 am 
	
"Structures, Spectroscopic Properties and Dioxygen Reactivity of 5- and 6-Coordinate Nonheme Iron(II) Complexes: A Combined Enzyme/Model Study of Thiol Dioxygenases" 
 
 
 
						
10:20 am - 10:30 am 
	
Discussion
 
 
						
10:30 am - 11:00 am 
	
Coffee Break
 
 
						
11:00 am - 11:20 am 
	
"PQQ Biosynthesis Is Resolved by the Discovery of Unprecedented Functions for the Enzyme PqqB" 
 
 
 
						
11:20 am - 11:30 am 
	
Discussion
 
 
						
11:30 am - 11:50 am 
	
"Insight into the E1 State of Mo Nitrogenase" 
 
 
 
						
11:50 am - 12:00 pm 
	
Discussion
 
 
						
12:00 pm - 12:20 pm 
	
"Understanding Ferryl Basicity in a Histidine-Ligated Peroxidase" 
 
 
 
						
12:20 pm - 12:30 pm 
	
Discussion
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:00 pm - 7:30 pm 
	
Evaluation Period 
Fill in GRS Evaluation Forms 
 
 
						
7:30 pm - 9:30 pm 
	
Metals on the Move: Sequestration, Affinity and Transport of Metals in and out of the Cell 
 
 
 
						
7:30 pm - 7:45 pm 
	
"Cu+-Specific CopB Transporter: Revisiting CopA and CopB Classification" 
 
 
 
						
7:45 pm - 7:50 pm 
	
Discussion
 
 
						
7:50 pm - 8:05 pm 
	
"Molecular Basis of Multiple Mitochondrial Dysfunctions Syndrome 2 (MMDS2): Impact of a Disease Causing Ile67Asn Mutation on BOLA3" 
 
 
 
						
8:05 pm - 8:10 pm 
	
Discussion
 
 
						
8:10 pm - 8:25 pm 
	
"Towards the Mechanisms of Copper Insertion in Plant Cytocrome c Oxidase" 
 
 
 
						
8:25 pm - 8:30 pm 
	
Discussion
 
 
						
8:30 pm - 8:45 pm 
	
"Investigating the Dependence of Proinsulin C-Peptide on Metal Micronutrients" 
 
 
 
						
8:45 pm - 8:50 pm 
	
Discussion
 
 
						
8:50 pm - 9:05 pm 
	
"Genetically Encoded Fluorescent Biosensors for Probing Cellular Chloride" 
 
 
 
						
9:05 pm - 9:10 pm 
	
Discussion
 
 
						
9:10 pm - 9:25 pm 
	
"Coordination Chemistry and Photoreactivity of Pacifibactin, a Marine Siderophore Identified Through Genome Mining" 
 
 
 
						
9:25 pm - 9:30 pm 
	
Discussion
 
 
						
	Sunday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 12:30 pm 
	
The Origins of Life: The Role of Metals in Evolution, Early Metabolism and Biogeochemical Cycles 
 
 
 
						
9:00 am - 9:20 am 
	
"Conformational Flexibility of Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase Revealed by Electron Microscopy" 
 
 
 
						
9:20 am - 9:30 am 
	
Discussion
 
 
						
9:30 am - 9:50 am 
	
"Unraveling the Interactions of the Physiological Reductant Flavodoxin with the Different Conformations of the Fe Protein in the Nitrogenase Cycle" 
 
 
 
						
9:50 am - 10:00 am 
	
Discussion
 
 
						
10:00 am - 10:20 am 
	
"Characterization of the Metalloproteome of the Marine Bacteria, Alteromonas " 
 
 
 
						
10:20 am - 10:30 am 
	
Discussion
 
 
						
10:30 am - 11:00 am 
	
Coffee Break
 
 
						
11:00 am - 11:20 am 
	
"Functional and Spectroscopic Investigations of CODH-I from Carboxydothermus hydrogenoformans " 
 
 
 
						
11:20 am - 11:30 am 
	
Discussion
 
 
						
11:30 am - 11:50 am 
	
"Flipping the Anaerobic Switch: [4Fe-4S] Cluster Mediated Oxygen Sensing and Global Transcription Regulation by FNR" 
 
 
 
						
11:50 am - 12:00 pm 
	
Discussion
 
 
						
12:00 pm - 12:20 pm 
	
"Conservation of Leu1's C-Terminus Is Essential for Its Recognition by the Cytosolic Iron-Sulfur Cluster Assembly Targeting Complex" 
 
 
 
						
12:20 pm - 12:30 pm 
	
Discussion
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm 
	
Departure