Session 1
Sunday evening |
Evolution of Mechanisms |
Martin Feder, Chair
- Martin Feder (Chicago)
"Evolution of the ‘Hsp70 Genome' in Drosophila"
- Marla Sokolowski (Toronto)
"Behavioral Evolution in Drosophila'
- Greg Gibson (NC State)
"Quantitative Genetic Dissection of Signal Transduction in Drosophila"
- Suzanne Rutherford (Washington)
"Hsp90 and Evolvability"
Session 2
Monday morning |
Post-Translational Mechanisms |
Francine B. Perler (New England Biolabs), Chair
- Victoria Derbyshire (Wadsworth Center)
"Molecular Symbiosis: Inteins and Introns"
- Paul Liu (Dalhousie, CA)
"Trans-Splicing and Intein Mobility"
- Shmuel Pietrokovski (Weizmann Inst.)
"Intein function hinted by their distribution and evolution"
- Ken Mills (Harvard Univ.)
"Role of intein structure in protein trans-splicing"
- Randy Hampton (UCSD)
"ER Protein Degradation in Regulation and Quality Control"
- Hanjo Hellman (Univ. of Texas at Austin)
"Function of the ubiquitin-proteasome pathway in plant hormone action"
Session 3
Monday evening |
Nuclear Hormone Receptors |
Ann E. Sluder, Chair
- Michael T. Bender (Georgia)
"Steroid Hormone Signaling in Drosophila Metamorphosis"
- Ann E. Sluder (Cambria Biosciences)
"Nuclear Receptors in Nematodes: Conservation, Divergence and Function"
- John T. Moore (Glaxo Wellcome)
"The Pregnane X Receptor: A Promiscuous Xenobiotic Receptor that Regulates CYP3A Expression"
- Kenneth Korach (NIEHS)
"Differential Regulation by the Alpha and Beta Forms of Mammalian Estrogen Receptor"
Session 4
Tuesday morning |
Chaperones and Stress Responses |
Richard I. Morimoto, Chair
- Richard I. Morimoto (Northwestern)
"The Stress of Polyglutamine Protein Aggregates on Protein Homeostasis in C. elegans"
- Linda Hendershot (St. Jude)
"Protein Folding in the ER: Sensing When Things Go Wrong"
- Laurence Goffin (Univ. of Melbourne)
"The unfolded protein response requires nuclear localization of the ERN1p/IRE1p receptor"
- Davis Ng (Penn State)
"Unfolded Protein Response Pathway"
- Jon Clardy (Cornell)
"Structure/Function of Immunophilins"
- Lawrence E. Hightower (Connecticut)
"The Heat Shock Response: Putting the Brakes on Inflammation"
POSTER SESSION ** -Late afternoon
Session 5
Tuesday evening |
Mechanisms in Symbiotic Relationships |
Ann Hirsch, Chair
- Ann Hirsch (UCLA)
"The Nitrogen-Fixing Symbiosis: How the Plants and the Microbe Get Together"
- Bonnie Bassler (Princeton)
"How bacteria talk to each other: regulation of gene expression by quorum sensing"
- Jamie Foster (Hawaii)
Vibrio and the Squid Light Organ
- Stephen Dobson (Kentucky)
"Impotence by Association: Tales of Cytoplasmic Incompatibility and Other Reproductive Manipulations by the Wolbachia Endosymbiont"
Session 6
Wednesday morning |
Regulatory Mechanisms in Physiological Ecology |
Anthony Zera, Chair
- Anthony Zera (Nebraska)
"Evolutionary Genetics of Endocrine Variation"
- Gretchen Hofmann (Ariz. State)
"Physiological ecology of molecular chaperones"
- Michael Purugganan (NC State)
"Molecular Evolutionary Ecology of Flower Development"
- H. Frederik Nijhout (Duke)
"The Evolution of Regulation in the Cell Cycle"
Session 7
Wednesday evening |
Variations on Transcription,
Translation, Replication, and DNA Repair |
Stephen Bell, Chair
- Yoshizumi Ishino (Osaka, Japan)
"DNA Replication and Recombination in Archaea"
- Isaac Cann (Osaka, Japan)
"Accessory Factors in DNA Replication at Extreme Temperatures"
- Stephen Bell (Cambridge, England)
"Transcriptional Regulation in Archaea"
- John Battista (LSU)
"DNA Repair and the Extreme Radioresistance of Deinococcus radiodurans"
Session 8
Thursday morning |
New Techniques to Address Regulatory Mechanisms |
Tom Muir, Chair
- Tom Muir (Rockefeller)
"Expressed Protein Ligation: Introduction of Biosensors"
- Tom Evans (New England Biolabs)
"Intein-Mediated Protein Ligation"
- Charles P. Scott (Pennsylvania State Univ.)
"Intracellular cyclic peptide libraries"
- Jun Qin (Baylor)
"Biophysics Meets Biochemistry in the Post-Genomics Era"
- Volker Heinrichs (Maxygen)
"Rapid Evolution of Selective Proteins Through Molecular Breeding"
BANQUET
Session 9
Thursday evening |
Regulatory Mechanisms Involving RNA |
Frank Slack, Chair
- Frank Slack (Yale)
"Control of Development by Small RNAs: Oddities or Emissaries"
- Ya-Ming Hou (Thomas Jefferson)
"Transfer RNA and Pathogenicity Islands"
- Phillip D. Zamore (U. Mass.)
"RNAi: an In Vitro Approach to Understanding Mechanism"
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