The "Biology of 14-3-3 Proteins" meeting focuses on a family of highly conserved molecules - found in all eukaryotic cells. The common theme describing 14-3-3 protein function is that they act by binding specific target proteins. Interaction in most cases is regulated by phosphorylation of these targets.

14-3-3 proteins are involved in an impressively diverse range of functions, including cell division, apoptosis, signal transduction, transmitter release, receptor function, ion channel physiology, gene expression, transmitter synthesis, neurodegenerative diseases and enzyme activation/protection. 14-3-3 proteins are being studied on a broad front, involving plants, yeast and vertebrates and a similarly broad range of systems and functions. The broad nature of 14-3-3 research means that investigators working on 14-3-3 proteins in the vertebrate nervous system do not typically meet with those working on in plants, thereby missing the opportunity to be stimulated by new approaches, experiences and findings from a distantly related program. This cross-fertilization will enrich research in this area by promoting discussion and enhancing the exchange of ideas and new discoveries between these scientists in the stimulating setting of a Gordon Research Conference.