Sunday
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2:00 pm - 9:00 pm |
Arrival and Check-in
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 7:40 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
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7:40 pm - 9:30 pm |
Metabolism and Bone Cells
Discussion Leader: Fanxin Long (Children's Hospital of Philadelphia, USA)
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7:40 pm - 7:45 pm |
Introduction by Discussion Leader
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7:45 pm - 8:10 pm |
Brendan Lee (Baylor College of Medicine, USA)
"Multi-omic Approach to Defining Novel Skeletal Human Phenotypes"
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8:10 pm - 8:20 pm |
Discussion
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8:20 pm - 8:45 pm |
Geert Carmeliet (KU Leuven, Belgium)
"Skeletal Cell Metabolism: Bystander or Driver"
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8:45 pm - 8:55 pm |
Discussion
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8:55 pm - 9:20 pm |
Gerard Karsenty (Columbia University, USA)
"Embryogenesis and Homeostasis"
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9:20 pm - 9:30 pm |
Discussion
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Monday
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7:30 am - 8:30 am |
Breakfast
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8:30 am - 9:00 am |
Group Photo
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9:00 am - 12:30 pm |
Development of Skeleton and Teeth
Discussion Leader: Karen Lyons (University of California, Los Angeles, USA)
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9:00 am - 9:05 am |
Introduction by Discussion Leader
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9:05 am - 9:30 am |
Andrei Chagin (Karolinska Institute, Sweden)
"Evolution and Function of Secondary Ossification Centers"
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9:30 am - 9:40 am |
Discussion
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9:40 am - 10:05 am |
Joel Boerckel (University of Pennsylvania, USA)
"The Mechanobiology of Bone Development"
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10:05 am - 10:15 am |
Discussion
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10:15 am - 10:50 am |
Coffee Break
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10:50 am - 11:15 am |
Véronique Lefebvre (Children's Hospital of Philadelphia, USA)
"Key Roles for the SOXC Genes in Developmental and Adult Bone Formation"
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11:15 am - 11:25 am |
Discussion
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11:25 am - 11:50 am |
Wanida Ono (University of Texas Health Science Center at Houston School of Dentistry, USA)
"PTHrP, Stem Cells and Tooth Development"
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11:50 am - 12:00 pm |
Discussion
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12:00 pm - 12:10 pm |
Short Talk Selected from Poster Abstracts
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12:10 pm - 12:15 pm |
Discussion
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12:15 pm - 12:25 pm |
Short Talk Selected from Poster Abstracts
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12:25 pm - 12:30 pm |
Discussion
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12:30 pm - 1:30 pm |
Lunch
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1:30 pm - 4:00 pm |
Free Time
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3:00 pm - 4:00 pm |
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Deneen Wellik (University of Wisconsin-Madison, USA) and Aris Economides (Regeneron Pharmaceuticals, Inc., USA)
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4:00 pm - 6:00 pm |
Poster Session
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6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 9:30 pm |
Origin and Fate of Bone Cells
Discussion Leader: Deneen Wellik (University of Wisconsin-Madison, USA)
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7:30 pm - 7:35 pm |
Introduction by Discussion Leader
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7:35 pm - 8:00 pm |
Vicki Rosen (Harvard School of Dental Medicine, USA)
"The Secreted Life of Periosteal BMP2"
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8:00 pm - 8:10 pm |
Discussion
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8:10 pm - 8:35 pm |
Sarah Dallas (University of Missouri-Kansas City, USA)
"Osteoclast and Osteocyte Dynamics in Bone"
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8:35 pm - 8:45 pm |
Discussion
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8:45 pm - 9:10 pm |
Maria Almeida (University of Arkansas for Medical Sciences, USA)
"The Role of NAD in Mesenchymal Cells from Bone Development to Aging"
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9:10 pm - 9:15 pm |
Discussion
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9:15 pm - 9:25 pm |
Short Talk Selected from Poster Abstracts
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9:25 pm - 9:30 pm |
Discussion
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Tuesday
|
7:30 am - 8:30 am |
Breakfast
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9:00 am - 12:30 pm |
Cross Talks Among Hematopoietic, Endothelial and Bone Cells
Discussion Leader: Joy Wu (Stanford University School of Medicine, USA)
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9:00 am - 9:05 am |
Introduction by Discussion Leader
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9:05 am - 9:30 am |
Laura Calvi (University of Rochester, USA)
"Macrophage-Osteolineage Cell's Cross Talk in Skeletal Homeostasis and Aging"
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9:30 am - 9:40 am |
Discussion
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9:40 am - 10:05 am |
Anjali Kusumbe (University of Oxford, United Kingdom)
"Vascular Control of Skeletal Homeostasis and Regeneration"
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10:05 am - 10:15 am |
Discussion
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10:15 am - 10:50 am |
Coffee Break
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10:50 am - 11:15 am |
Matthew Greenblatt (Weill Cornell Medicine, USA)
"A Stem Cell Mediating Osteoblast Versus Adipocyte Lineage Commitment"
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11:15 am - 11:25 am |
Discussion
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11:25 am - 11:50 am |
Michelle McDonald (Garvan Institute of Medical Research, Australia)
"Osteomorphs and Osteoclast Recycling: A Mechanism for Rebound Bone Loss Following Withdrawal of Denosumab Therapy"
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11:50 am - 12:00 pm |
Discussion
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12:00 pm - 12:10 pm |
Short Talk Selected from Poster Abstracts
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12:10 pm - 12:15 pm |
Discussion
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12:15 pm - 12:25 pm |
Short Talk Selected from Poster Abstracts
|
12:25 pm - 12:30 pm |
Discussion
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12:30 pm - 1:30 pm |
Lunch
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1:30 pm - 4:00 pm |
Free Time
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4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
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7:30 pm - 9:30 pm |
Contribution of Bone Marrow Adipocytes and Stroma to Bone Homeostasis
Discussion Leader: Clifford Rosen (Maine Medical Center, USA)
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7:30 pm - 7:35 pm |
Introduction by Discussion Leader
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7:35 pm - 8:00 pm |
Steven Teitelbaum (Washington University School of Medicine, USA)
"Fat Talks to Bone"
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8:00 pm - 8:10 pm |
Discussion
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8:10 pm - 8:35 pm |
Ling Qin (University of Pennsylvania, USA)
"Marrow Adipogenic Lineage Precursor (MALP): A Master Regulator of Bone Metabolism and Marrow Environment"
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8:35 pm - 8:40 pm |
Discussion
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8:40 pm - 9:05 pm |
Michaela Reagan (Maine Medical Center, USA)
"Sclerostin and Bone Marrow Adipose Tissue"
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9:05 pm - 9:15 pm |
Discussion
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9:15 pm - 9:25 pm |
Short Talk Selected from Poster Abstracts
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9:25 pm - 9:30 pm |
Discussion
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Wednesday
|
7:30 am - 8:30 am |
Breakfast
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9:00 am - 12:30 pm |
Microenvironment and Metabolism of Tumors and Normal Cells
Discussion Leader: Amato Giaccia (University of Oxford, United Kingdom)
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9:00 am - 9:05 am |
Introduction by Discussion Leader
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9:05 am - 9:30 am |
Rachelle Johnson (Vanderbilt University Medical Center, USA)
"Impact of Tumor-Targeted Therapies on Skeletal Health"
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9:30 am - 9:40 am |
Discussion
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9:40 am - 10:05 am |
Theresa Guise (MD Anderson Cancer Center, USA)
"Pathological Bone Resorption: Effects on Glucose Metabolism"
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10:05 am - 10:15 am |
Discussion
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10:15 am - 10:50 am |
Coffee Break
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10:50 am - 11:15 am |
Stavroula Kousteni (Columbia University, USA)
"Role of the Osteoblastic Niche in Acute Myeloid Leukemia Transformation"
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11:15 am - 11:25 am |
Discussion
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11:25 am - 11:50 am |
Jesus Delgado-Calle (UAMS, USA)
"The Osteocyte as a Signaling Cell in the Tumor Bone Microenvironment"
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11:50 am - 12:00 pm |
Discussion
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12:00 pm - 12:10 pm |
Short Talk Selected from Poster Abstracts
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12:10 pm - 12:15 pm |
Discussion
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12:15 pm - 12:25 pm |
Short Talk Selected from Poster Abstracts
|
12:25 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
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1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:00 pm - 7:30 pm |
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
|
7:30 pm - 9:30 pm |
The Tendon-Bone Unit and Healing Processes
Discussion Leader: Elazar Zelzer (Weizmann Institute of Science, Israel)
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7:30 pm - 7:35 pm |
Introduction by Discussion Leader
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7:35 pm - 8:00 pm |
Megan Killian (University of Michigan, USA)
"Development, Disease, and Healing of the Enthesis"
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8:00 pm - 8:10 pm |
Discussion
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8:10 pm - 8:35 pm |
Matthew Silva (Washington University School of Medicine, USA)
"Role of Osteoblast Lineage Cell Proliferation in Fracture Healing"
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8:35 pm - 8:45 pm |
Discussion
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8:45 pm - 8:55 pm |
Short Talk Selected from Poster Abstracts
|
8:55 pm - 9:00 pm |
Discussion
|
9:00 pm - 9:10 pm |
Short Talk Selected from Poster Abstracts
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9:10 pm - 9:15 pm |
Discussion
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9:15 pm - 9:25 pm |
Short Talk Selected from Poster Abstracts
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9:25 pm - 9:30 pm |
Discussion
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Thursday
|
7:30 am - 8:30 am |
Breakfast
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9:00 am - 12:30 pm |
Rare Bone Diseases
Discussion Leader: Maurizio Pacifici (Children's Hospital of Philadelphia, USA)
|
9:00 am - 9:05 am |
Introduction by Discussion Leader
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9:05 am - 9:30 am |
Thomas Gardella (Massachusetts General Hospital, USA)
"PTHR1 Mutations in Skeletal Disease and Potential Paths to Therapy"
|
9:30 am - 9:40 am |
Discussion
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9:40 am - 10:05 am |
Laurence Legeai-Mallet (Institut Imagine-Inserm U1163-Université de Paris, France)
"Latest News Regarding FGFR3 Related Disorders"
|
10:05 am - 10:15 am |
Discussion
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10:15 am - 10:50 am |
Coffee Break
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10:50 am - 11:15 am |
Aris Economides (Regeneron Pharmaceuticals, Inc., USA)
"New Insights into the Mechanism of Signaling by Fibrodysplasia Ossificans Progressiva (FOP)-mutant ACVR1"
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11:15 am - 11:25 am |
Discussion
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11:25 am - 11:50 am |
Benjamin Levi (University of Texas Southwestern Medical Center, USA)
"The Nervous Niche of Musculoskeletal Tissue in Repair and Disrepair"
|
11:50 am - 11:55 am |
Discussion
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11:55 am - 12:05 pm |
Short Talk Selected from Poster Abstracts
|
12:05 pm - 12:10 pm |
Discussion
|
12:10 pm - 12:20 pm |
Short Talk Selected from Poster Abstracts
|
12:20 pm - 12:30 pm |
Discussion
|
12:30 pm - 1:30 pm |
Lunch
|
1:30 pm - 4:00 pm |
Free Time
|
4:00 pm - 6:00 pm |
Poster Session
|
6:00 pm - 7:00 pm |
Dinner
|
7:30 pm - 9:30 pm |
Regeneration of Bone
Discussion Leader: Yingzi Yang (Harvard School of Dental Medicine, USA)
|
7:30 pm - 7:35 pm |
Introduction by Discussion Leader
|
7:35 pm - 8:00 pm |
Jerome Guicheux (University of Nantes, Inserm UMR 1229, France)
"Novel Modalities of Joint Regeneration: When Developmental Biologists meet Tissue Engineers"
|
8:00 pm - 8:10 pm |
Discussion
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8:10 pm - 8:35 pm |
Kurt Hankenson (University of Michigan, USA)
"Callus Size Regulation During Compromised Bone Healing"
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8:35 pm - 8:45 pm |
Discussion
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8:45 pm - 9:10 pm |
Regina Brunauer (Texas A&M University, USA)
"Exploring the Microcosm of Mouse Digit Regeneration to Understand Bone Aging"
|
9:10 pm - 9:20 pm |
Discussion
|
9:20 pm - 9:30 pm |
Closing Remarks
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Friday
|
7:30 am - 8:30 am |
Breakfast
|
9:00 am |
Departure
|