Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Enabling
Technologies for Functional Glycomics
7:40 pm - 8:05 pm
"Human Glycomics and Deciphering the Expression and Biological Recognition of Glycans"
8:05 pm - 8:15 pm
Discussion
8:15 pm - 8:40 pm
"A Systems Approach to Carbohydrate Synthesis and Analysis"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:15 pm
"Exploiting Anti-Glycan Immunity to Improve Cancer Care"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Glycosylation
and Synthetic Methodology
9:00 am - 9:25 am
"From Stereocontrolled Glycosylation to the Automated Oligosaccharide Synthesis"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Protecting Group Free Transformations of Reducing Sugars in Aqueous Solution"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Photo-Induced Glycosylation Reactions"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
"Synthesis of Glycoconjugates for Elucidation of Oligosaccharide Functions"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Stereoselective Synthesis of Kdo Glycoside"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Chemical Promoters for Controlling Selectivity in Glycosylation Reactions"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Chemistry on Protection and Functionalization of Free Sugars"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:55 pm
"Carbohydrate Recognition and Signaling in the Brain"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:30 pm
"Human Influenza Virus Receptors"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:05 pm
"Discovery of Host Cell Glycans Recognized by Bacterial Toxins"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Chemical Editing of the Glycocalyx to Influence Stem Cell Differentiation"
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Enzymatic
and Chemoenzymatic Assembly of Glycans
9:00 am - 9:25 am
"Biosynthetic Studies of Oxetanocin A"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Mutant Glycosyltransferases and Hexosaminidases in the Synthesis of Advanced Glycomaterials"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Switching Enzyme Specificity from Phosphate to Resveratrol Glucosylation via Domain-Shift"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
"Discovering New Glycosidases Through Metagenomics and Gene Synthesis"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Enzymatic Modular Assembly of Human Blood Antigens"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"New Insights into the Process and Function of Tryptophan C-Mannosylation Provided by Yeast Engineered to Perform This Protein Modification"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Synthesis and Application of Oligosaccharides Related to Plant Cell Wall Glycans"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Molecular Recognition in Protein-Carbohydrate Interactions
7:30 pm - 7:55 pm
"Microbial Lectins Binding to Lewis Glycotopes: Experimental and Computational Study"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:30 pm
"Glycosyltransferases as Tools to Identify Cell Surface Lactosaminyl Glycans"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:05 pm
"Chemoenzymatic Detection of Glycans: Methods and Applications"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Using Chemical Biology to Understand and Apply Protein O-Glycosylation"
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Carbohydrate Vaccines and Glyco-Immunology
9:00 am - 9:25 am
"From Biologicals to Pharmaceuticals: A Medicinal Chemistry Approach to Carbohydrate-Conjugate Vaccines Against Streptococcus pneumoniae and Other Bacteria"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Glycopeptide Vaccines for Cancer Immunotherapy"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Real-Time Analysis on Drug-Antibody Ratio of Antibody-Drug Conjugates for Synthesis, Process Optimization, and Quality Control"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
"An Entirely Carbohydrate-Recognizing Monoclonal Antibody"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Anti-Sialyl-Tn Monoclonal Antibody-Drug Conjugates (ADCs) Demonstrate Tumor Specificity In Vitro and In Vivo Antitumor Efficacy"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Precision Mapping of MUC1 Glycopeptides Expressed by Non-Small Cell Carcinoma"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
"Carbohydrate Involvement in Group B Streptococcus (GBS) Pathogenesis"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Structural
Chemistry and Biology of Carbohydrates
7:30 pm - 7:55 pm
"Computational and Biophysical Insight into Glycan Specificity: The Role of Entropy and Avidity"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:30 pm
"Capsular Polysaccharides of the Nosocomial Pathogen Acinetobacter baumannii : Structure, Genetics, and Cleavage by Bacteriophages"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:05 pm
"Can Advances in Mass Spectrometry Unlock the Mysteries of Glycans?"
9:05 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"Structures of Human O-GlcNAcase and Its Complexes Reveal a New Substrate Recognition Mode"
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Synthetic
Probes for Deciphering Carbohydrate Functions
9:00 am - 9:25 am
"Synthetic Substrates for the Analysis of Glycan Processing Enzymes in the ER"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Synthesis of Designer Polysaccharides"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
"Synthesis of Rare Sugar AAT Containing Bacterial Glycoconjugates"
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
"Carbohydrate Chemistry for RNA Interference: Synthesis, Structure and Biological Activity of Amide-Linked RNA"
11:20 am - 11:30 am
Discussion
11:30 am - 11:55 am
"Synthesis and Characterization of Specific Heparan Sulfate-Protein Interactions"
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:15 pm
"Palladium-Catalyzed Direct Stereoselective Synthesis of Deoxyglycosides from Glycals"
12:15 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Glycans
in Biotechnology and Medicine
7:30 pm - 7:55 pm
"Developing an Enzyme-Based Approach to Synthetize Glycosaminoglycans"
7:55 pm - 8:05 pm
Discussion
8:05 pm - 8:30 pm
"Nanomedicine Targeting Intracellular Glycoenzymes"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 8:50 pm
"Glycosylation of a Subfragment Peptide of Type I Collagen"
8:50 pm - 8:55 pm
Discussion
8:55 pm - 9:20 pm
"Three Different Glycomimetic Drugs in Clinical Trials for Inflammatory Disorders and Cancer"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure