Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Glycans with Diverse Biological Functions
7:40 pm - 8:00 pm
"Chemo-Enzymatic Synthesis of Complex Glycans to Probe Host-Virus Interactions"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"GlycoRNA Biology on the Cell Surface"
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:45 pm
"Structure and Function of Hyaluronan Synthase: Insights Into Glycosaminoglycan Synthesis and Length Control"
8:45 pm - 8:55 pm
Discussion
8:55 pm - 9:15 pm
"Human Lectins as Glycan Probes"
9:15 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Automation and Machine Learning
9:00 am - 9:20 am
"Automated Solution-Phase Glycan Synthesis"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Carbohydrate Foldamers and Assemblies"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Pseudo-Polysaccharides for Biomaterials and Bioconjugates"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Trifluoromethyl Radical Carbohydrate Footprinting Detects Glycan Interactions"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"From Stereocontrolled Glycosylation to Automated Chemical Synthesis"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Urine IgG Glycan Profiles as Powerful Biomarkers Differentiating Systemic Lupus Erythematosus Disease Course"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Urine IgG Glycan Profiles as Powerful Biomarkers Differentiating Systemic Lupus Erythematosus Disease Course"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Understanding and Exploiting Glycan Biosynthesis
7:30 pm - 7:50 pm
"Precision In Vivo Glycoengineering Advances the Development of Targeted Protein Degraders"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Hyperglycemic Remodeling of O-GlcNAc Glycoproteins: Tools and Targets in Metabolic Diseases"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Substrate-Controlled Strategy Enabling Access to the Synthesis of Asymmetrically Branched Human Milk Oligosaccharides"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Chemical and Biochemical Tools to Study the Role of Exopolysaccharides in Bacterial Biofilm Formation"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Chemical Precision Tools to Dissect Human Polypeptide GalNAc Transferases"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Unnatural Glycoconjugates
9:00 am - 9:20 am
"Leveraging Mucin Glycans to Enhance Innate Immunity"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Synthesis of Substrate Analogues for Inhibition of Cysteine Ligase (MshC) in Mycobacterium Tuberculosis "
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Therapeutic Potential of Sulfated and Hydrophobic Paromomycin Ligands for Type Ⅰ Diabetes under the Challenge of Upregulated Heparanase"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Using Fluorogenic Monosaccharides to Detect and Identify Bacterial Glycosidases"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Liquid Glycan Array (LiGA) and Liquid Lectin Array (LiLA) for Exploration of Glycan-Protein Interaction In Vivo "
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Bioengineered Heparan Sulfate Glycomimetics for Analysis and Regulation of Growth Factor Activity"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Development and Commercialization of Polysaccharide Conjugate Vaccines: Incorporation of Higher Throughput, Automated Lab Scale Models"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
7:30 pm - 7:50 pm
"Stereoselective Glycosylation by Cooperative Atom Transfer Catalysis"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Selective Saccharide Hydrolysis by Nanogel Catalysts"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Weaving Noncovalent Interactions into Selective Carbohydrate Synthesis"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Stapling ß-Glucans Improves Antibody binding"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Chemoenzymatic Synthesis of Site-Selectively Modified Glycoforms of Antibodies for Probing Functions"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Enforced E-Selectin Ligand Expression Enhances Homing and Anti-Tumor Efficacy of Adoptively Transferred T Cells"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Harnessing Siglecs to Induce B Cell Tolerance"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Wound Healing with alpha-Gal Liposomes"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Development of Proximity Labeling-Based Cell Surface Glycan Engineering and Its Application for Cancer Immune Therapy"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Engineered Human Sialidase as a Novel Cancer Therapeutic Strategy to Enhance Antitumor Immunity by Cleaving Immunosuppressive Sialoglycans"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
"Development of a New Pharmaceutical Lead Against Non-Tuberculous Mycobacterium Disease by Late-Stage Boron-Mediated Aglycon Delivery"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Sweet Targets: Biocatalytic Methods for Glycosylating Nucleoside Analogues"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Chemistry to Access Bioactive Molecules
7:30 pm - 7:50 pm
"Disapproval of the Alleged Structure and Antifreeze Activity of Xylomannans via Total Synthesis"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Rapid Synthesis of Glycopeptides using Flow Chemistry"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Development of Carbohydrate Based Immunotherapy"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Glycomimetics as Putative Substrates of Glycosyl Hydrolases"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Synthesis of Biologically Active Carbohydrates and Structure-Activity Relationship Studies Toward the Creation of Pharmaceutical Leads"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
9:00 am - 9:20 am
"Advancing Glycomics and Glycoproteomics through Innovation in Chemical Tagging Approaches"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Carbohydrate Structure Determination, From Quantum Chemistry and Gas Phase Chemical Kinetics to Glycobiology"
9:50 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Spatial Imaging and Analysis of GlycoRNA in Single Cells"
10:10 am - 10:15 am
Discussion
10:15 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"NMR-Based Discovery of a Unique Glycan-Water Interaction Manner"
11:05 am - 11:15 am
Discussion
11:15 am - 11:25 am
"Toward Single Molecule Sequencing by Direct Imaging"
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
"The Power of NMR and MD in Molecular Recognition: The Case of Siglec-7–F. nucleatum Interaction"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Cell-Surface Glycans Are Quantitative Reporters of Golgi Dysfunction in Single Cells"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Microbial and Viral Glycans
7:30 pm - 7:50 pm
"Modulating the Innate Immune System with Carbohydrates"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Deciphering Mechanisms of Peptidoglycan Metabolism Across Microbiota"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:35 pm
"Chemical Biology Studies of Bacterial Glycan Pseudaminic Acid"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"A Sweet Coating: Molecular Mechanism of Vibrio Biofilm Matrix Assembly"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Unveiling Giant Viruses Glycosylation Machinery: First Hints into One of the Mimivirus Polysaccharide Biosynthesis"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure
