| SATURDAY |
| 1:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Keynote Address |
| Discussion Leader: Shirin Doroudgar (San Diego State University) |
| 3:45 pm - 4:15 pm | Jeffery D. Molkentin (Howard Hughes Medical Institute)
"Calcium and the regulation of cardiac hypertrophy"
|
| 4:15 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | New Frontiers in Excitation-Contraction Coupling |
| Discussion Leader: Elizabeth Bode (University of Manchester) and Viktoriia Kyrychenko (UMDNJ-NJMS)
|
| 7:30 pm - 7:46 pm | Jerry Curran (The Ohio State University)
"The role of EHD proteins in cardiac excitability and disease"
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| 7:46 pm - 7:54 pm | Discussion |
| 7:54 pm - 8:10 pm | Prakash Subramanyam (Columbia University)
"Engineering the composition of L-type (CaV1.2) channels in heart cells using split intein-mediated protein trans-splicing"
|
| 8:10 pm - 8:18 pm | Discussion |
| 8:18 pm - 8:34 pm | Neha Abrol (Loyola University Chicago)
"The Role of lethal phospholamban R9C mutation in SERCA dysfunction"
|
| 8:34 pm - 8:42 pm | Discussion |
| 8:42 pm - 8:58 pm | Jessica Clarke (University of Manchester)
"The role of Ca buffering and ICa,L in the age associated decrease in Ca transient amplitude in atrial myocytes"
|
| 8:58 pm - 9:06 pm | Discussion |
| 9:06 pm - 9:22 pm | Lars Kaestner (Saarland University)
"Functional and morphological preservation of adult ventricular myocytes in culture"
|
| 9:22 pm - 9:30 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Hypertrophy, Heart Failure and Cardioprotection |
| Discussion Leaders: Cosmo Damiano Del Voscovo (University of Lausanne) and Premi Shekar (University of Kentucky)
|
| 9:00 am - 9:16 am | Faye Drawnel (Babraham Institute)
"IP3-induced calcium release engages a pro-hypertrophic autoamplifying loop that relieves miR-133a mediated suppression of IP3RII calcium channels"
|
| 9:16 am - 9:24 am | Discussion |
| 9:24 am - 9:40 am | Jason Yang (University of Virginia)
"PKA catalytic subunit compartmentation regulates contractile and hypertrophic responses to β-Adrenergic signaling"
|
| 9:40 am - 9:48 am | Discussion |
| 9:48 am - 10:04 am | Fu Siong Ng (Washington University in St. Louis)
"Accelerated ischemia-induced electrophysiological changes and slower recovery following reperfusion in failing human myocardium"
|
| 10:04 am - 10:12 am | Discussion |
| 10:12 am - 10:28 am | Swathi Appachi (National Heart Lung and Blood Institute)
"Non-nuclear estrogen receptor activation is protective in cardiac ischemia-reperfusion injury in mice"
|
| 10:28 am - 10:36 am | Discussion |
| 10:36 am - 10:52 am | Mirko Volkers (San Diego State University)
"Cardioprotection by Optimizing mTOR activity"
|
| 10:52 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:45 pm | Scientific Writing Workshop: Grant Writing & Manuscript Preparation |
| Discussion Leader: Mark Kohr (Johns Hopkins University) |
| Grant Writing Panel Discussion: United States and Europe |
| 1:30 pm - 1:40 pm | Howard Rockman (Duke University)
"How to write grants that lead to great papers: An Editor's perspective"
|
| 1:40 pm - 1:50 pm | Barbara Casadei (Oxford University)
"How to write a grant that gets funded"
|
| 1:50 pm - 2:10 pm | Discussion |
| Manuscript Preparation in the Cardiovascular Sciences |
| 2:10 pm - 2:30 pm | David Eisner (University of Manchester)
"Fraud and impact factors: two ways to mess up science"
|
| 2:30 pm - 2:45 pm | Discussion |
| 2:45 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |