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Catecholamines

Gordon Research Conference

Molecular, Circuit, Behavior and Brain Disorders

August 24 - 29, 2025

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GRC Education Requirements: Undergraduates or those who have not obtained a bachelor's degree in science/engineering (or acceptable equivalent) are not eligible to apply to attend Gordon Research Conferences or Seminars.

Chair

Vice Chairs

and

Grand Summit Hotel at Sunday River

97 Summit Road

Newry, Maine, United States

Venue and Travel Information

Venue

Office Manager: Samantha Arellano

Office Manager Email: sundayriver_sm@grc.org

Office Phone:

Application Information

The application deadline for this meeting was July 27, 2025. You may still submit an application, which may be considered by the conference chair if there is still room available.

Conference Description

The Catecholamines GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes an array of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

Related Meeting

This GRC will be held in conjunction with the "Catecholamines" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Conference Program

Sunday
2:00 pm - 9:00 pm	Arrival and Check-in
6:00 pm - 7:00 pm	Dinner
7:30 pm - 7:40 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm	Keynote Session: Catecholamine Mechanisms Across Circuits and Behavior Discussion Leader:
7:40 pm - 7:50 pm	Introduction by Discussion Leader
7:50 pm - 8:30 pm	"Craving and Control: How Brain Circuits Shape Addiction Risk"
8:30 pm - 8:40 pm	Discussion
8:40 pm - 9:20 pm	"Brain Reward Signals for Natural and Drug Reinforcers"
9:20 pm - 9:30 pm	Discussion
Monday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Catecholamine Functions in Innate and Learned Behaviors Discussion Leader:
9:00 am - 9:05 am	Introduction by Discussion Leader
9:05 am - 9:20 am	"The Neuromodulatory Responses of Inheritable Stress-Induced Olfactory Plasticity"
9:20 am - 9:25 am	Discussion
9:25 am - 9:45 am	"Locus Coeruleus Norepinephrine Neuron Modulation of Cortical Taste Processing"
9:45 am - 9:55 am	Discussion
9:55 am - 10:15 am	"Dopamine-Associated Contributions to Behavioral, Cellular, and Transcriptional Patterns of Cocaine Renewal"
10:15 am - 10:25 am	Discussion
10:25 am - 10:55 am	Coffee Break
10:55 am - 11:10 am	"The Locus Coeruleus: Norepinephrine System Regulates Decision-Making in a Rodent Virtual Height Threat Task"
11:10 am - 11:15 am	Discussion
11:15 am - 11:35 am	"Norepinephrine Regulates Mutual Social Interactions"
11:35 am - 11:45 am	Discussion
11:45 am - 12:05 pm	"Dopaminergic Control of Punishment-Resistant Reward-Seeking"
12:05 pm - 12:15 pm	Discussion
12:15 pm - 12:30 pm	General Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Catecholamine Systems in Neurodegeneration and Aging Discussion Leader:
7:30 pm - 7:35 pm	Introduction by Discussion Leader
7:35 pm - 7:50 pm	"Molecular and Spatial Profiling of the Human Locus Coeruleus Using Single Nucleus and High-Resolution Spatial Transcriptomics"
7:50 pm - 7:55 pm	Discussion
7:55 pm - 8:15 pm	"Astrocyte Contributions to GABAergic Abnormalities in Huntington’s Disease"
8:15 pm - 8:25 pm	Discussion
8:25 pm - 8:45 pm	"Compensatory Locus Coeruleus Hyperactivity Drives Behavioral Symptoms in Prodromal Alzheimer's Disease"
8:45 pm - 8:55 pm	Discussion
8:55 pm - 9:15 pm	"Unraveling the Role of the Dorsal Raphe Nucleus in Anxiety and Depression Comorbidity Within Parkinson's Disease"
9:15 pm - 9:25 pm	Discussion
9:25 pm - 9:30 pm	General Discussion
Tuesday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Catecholamine Circuits and Cell Types Across the Lifespan Discussion Leader:
9:00 am - 9:05 am	Introduction by Discussion Leader
9:05 am - 9:20 am	"The Role of Altered Norepinephrine Signaling in Motor Dysfunction in Rett Syndrome"
9:20 am - 9:25 am	Discussion
9:25 am - 9:45 am	"The Weight of Histones in Shaping Lifelong Susceptibility to Stress"
9:45 am - 9:55 am	Discussion
9:55 am - 10:15 am	"Mesolimbic Dopamine and Non-Dopamine Neuronal Activation During Seeking Behavior"
10:15 am - 10:25 am	Discussion
10:25 am - 10:55 am	Coffee Break
10:55 am - 11:15 am	"Molecular Mechanism of Targeting the Dopamine Transporter by Selective Autophagy"
11:15 am - 11:25 am	Discussion
11:25 am - 11:45 am	"Calcium Transients in Microglia Drive Repetitive and Anxiety Behaviors"
11:45 am - 11:55 am	Discussion
11:55 am - 12:15 pm	"A Developmental View of Locus Coeruleus Heterogeneity"
12:15 pm - 12:25 pm	Discussion
12:25 pm - 12:30 pm	General Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Technologies to Probe Catecholamine Systems Discussion Leader:
7:30 pm - 7:40 pm	Introduction by Discussion Leader
7:40 pm - 8:00 pm	"Spatially-Resolved Molecular Approaches for Defining Cellular Heterogeneity Across the Mesolimbic Dopamine System in the Human Brain"
8:00 pm - 8:10 pm	Discussion
8:10 pm - 8:30 pm	"Mapping Active Cells and Synaptic Dynamics"
8:30 pm - 8:40 pm	Discussion
8:40 pm - 9:00 pm	"Spying on Neuromodulator Dynamics in vivo by Constructing Multi-Color GRAB Sensors"
9:00 pm - 9:10 pm	Discussion
9:10 pm - 9:30 pm	General Discussion
Wednesday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Group Photo
9:00 am - 12:30 pm	Catecholamine Circuits in Psychiatric and Addiction Behaviors Discussion Leader:
9:00 am - 9:20 am	"Interactions Between Striatal Dopamine and Acetylcholine in Hallucination-Like Perception"
9:20 am - 9:30 am	Discussion
9:30 am - 9:50 am	"The Brain Dopamine System in Opioid Use Disorder Recovery"
9:50 am - 10:00 am	Discussion
10:00 am - 10:20 am	"Epigenetic Reprogramming Alters Striatal Gene Responses in Cocaine Addiction"
10:20 am - 10:30 am	Discussion
10:30 am - 11:00 am	Coffee Break
11:00 am - 11:20 am	"Predicting Stress-Induced Anhedonia from Cortical Dynamics and Facial Expression"
11:20 am - 11:30 am	Discussion
11:30 am - 11:50 am	"Opioid Induced Plasticity and Behavior in Noradrenergic Systems"
11:50 am - 12:00 pm	Discussion
12:00 pm - 12:20 pm	"Dopamine Mechanisms Underlying Cue-Elicited Compulsive Alcohol Seeking and Relapse"
12:20 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Early Career Investigator Presentations Discussion Leader:
7:30 pm - 7:45 pm	Late-Breaking Topic
7:45 pm - 7:50 pm	Discussion
7:50 pm - 8:05 pm	Late-Breaking Topic
8:05 pm - 8:10 pm	Discussion
8:10 pm - 8:25 pm	Late-Breaking Topic
8:25 pm - 8:30 pm	Discussion
8:30 pm - 8:45 pm	"Regulation of Decision Threshold by Locus Coeruleus"
8:45 pm - 8:50 pm	Discussion
8:50 pm - 9:05 pm	"Hunger Accelerates Reward Learning Through a Movement Specific Dopamine Signal"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:25 pm	"Expression Patterns of Noradrenergic Receptors Shape Cortical Interneuron Responses to Reinforcements"
9:25 pm - 9:30 pm	Discussion
Thursday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Business Meeting Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm	Catecholamine Systems, Synapses, and Neuromodulatory Mechanisms Discussion Leader:
9:00 am - 9:05 am	Introduction by Discussion Leader
9:05 am - 9:20 am	"Noradrenergic Modulation of Dopaminergic Neurons in the Dorsal Raphe Nucleus Contributes to Stress-Induced Reward Insensitivity"
9:20 am - 9:25 am	Discussion
9:25 am - 9:45 am	"Distinguishing the Roles of Catecholamines Across Multiple Cognitive and Motivational Domains"
9:45 am - 9:55 am	Discussion
9:55 am - 10:15 am	"Corticonigral Projections Recruit Dopaminergic Neurons for Auditory Threat Learning"
10:15 am - 10:25 am	Discussion
10:25 am - 10:55 am	Coffee Break
10:55 am - 11:10 am	"Molecular and Cellular Control of Distinct Serotonin Release Modes"
11:10 am - 11:15 am	Discussion
11:15 am - 11:35 am	"Facilitating Striatal Plasticity with Salient Stimuli"
11:35 am - 11:45 am	Discussion
11:45 am - 12:05 pm	"Evolving Views of a Special Relationship Between Neuromodulatory Neurons and the Integrated Stress Response"
12:05 pm - 12:15 pm	Discussion
12:15 pm - 12:30 pm	General Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Catecholamines in Pain and Nociception Discussion Leader:
7:30 pm - 7:50 pm	"Dopamine at the Intersection of Alcohol and Pain"
7:50 pm - 8:00 pm	Discussion
8:00 pm - 8:20 pm	"An Amygdala-Accumbens Axis for Aversion to Pain"
8:20 pm - 8:30 pm	Discussion
8:30 pm - 8:50 pm	"Dorsal Root Ganglion RGS4 Regulates Peripheral Nerve Injury-Associated Molecular and Behavioral Maladaptations in Murine Pain Models"
8:50 pm - 9:00 pm	Discussion
9:00 pm - 9:20 pm	"Endogenous Opioid Regulation of Locus Coeruleus-Mediated Analgesia"
9:20 pm - 9:30 pm	Discussion
Friday
7:30 am - 8:30 am	Breakfast
9:00 am	Departure

Contributors

Research reported in this publication was supported by the National Institute On Drug Abuse of the National Institutes of Health under Award Number R13DA063291. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Conference Links

Conference History Catecholamines (GRS) Contribute Financially to This Conference

Conference Fees

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Poster Information

Poster sessions are an integral part of the our conferences, and offer all conferees an opportunity to discuss their research.

Preparing your GRC poster

Funding Opportunities

Financial assistance is available beginning in 2026 for qualified applicants through the Carl Storm Opportunity Fellowships program. Learn more.

Registration Fees

Conferee Single Room:

$1,665.00

Conferee Shared Room:

$1,300.00

Conferee Off-Site:

$930.00

Guest Single Room:

$1,475.00

Guest Shared Room:

$1,110.00

Guest Off-Site:

$740.00

Child 4-12 yrs Shared Room:

$555.00

Child 4-12 yrs Off-Site:

$370.00

Child Under 4 yrs Shared Room:

Free

Child Under 4 yrs Off-Site:

Free

Bus Arriving:

$62.00

Bus Departing:

$62.00

Additional Fee Info

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