Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Catecholamine Mechanisms Across Circuits and Behavior
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:30 pm
"Craving and Control: How Brain Circuits Shape Addiction Risk"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:20 pm
"Brain Reward Signals for Natural and Drug Reinforcers"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Catecholamine Functions in Innate and Learned Behaviors
9:00 am - 9:20 am
"Locus Coeruleus Norepinephrine Neuron Modulation of Cortical Taste Processing"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"A Thalamostriatal Circuit Signals the Value of Avoidance Actions via Cholinergic Mechanisms"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Essential Sleep Features for Brain Remodeling"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Norepinephrine Regulates Mutual Social Interactions"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Is Love Blind: Dopamine Biases Threat Perception During Mating Proximity"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Dopaminergic Control of Punishment-Resistant Reward-Seeking"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hourâ„¢
The GRC Power Hourâ„¢ is designed to address the interests and needs of all scientists and the challenges they face in their careers. Specifically, the program promotes meaningful conversations amongst colleagues of all career stages about barriers to career advancement and strategies to support the professional growth of all members of the community. The GRC Power Hourâ„¢ is open to all conference participants.
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Catecholamine Systems in Neurodegeneration and Aging
7:30 pm - 7:50 pm
"Astrocyte Contributions to GABAergic Abnormalities in Huntington’s Disease"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Compensatory Locus Coeruleus Hyperactivity Drives Behavioral Symptoms in Prodromal Alzheimer's Disease"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Unraveling the Role of the Dorsal Raphe Nucleus in Anxiety and Depression Comorbidity Within Parkinson's Disease"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Mechanisms Underlying Selective Neuronal Pathogenesis in Huntington’s Disease"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Catecholamine Circuits and Cell Types Across the Lifespan
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
"A Developmental View of Locus Coeruleus Heterogeneity"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
"The Weight of Histones in Shaping Lifelong Susceptibility to Stress"
9:55 am - 10:05 am
Discussion
10:05 am - 10:25 am
"Dissecting Dopamine Neuron Connectivity Using Novel Mouse Genetics Tools"
10:25 am - 10:35 am
Discussion
10:35 am - 11:10 am
Coffee Break
11:10 am - 11:30 am
"Molecular Mechanism of Targeting the Dopamine Transporter by Selective Autophagy"
11:30 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"Making Dopamine Connections in Adolescence"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Technologies to Probe Catecholamine Systems
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Spatially-Resolved Molecular Approaches for Defining Cellular Heterogeneity Across the Mesolimbic Dopamine System in the Human Brain"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Mapping Active Cells and Synaptic Dynamics"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:00 pm
"Spying on Neuromodulator Dynamics in vivo by Constructing Multi-Color GRAB Sensors"
9:00 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Catecholamine Circuits in Psychiatric and Addiction Behaviors
9:00 am - 9:20 am
"Interactions Between Striatal Dopamine and Acetylcholine in Hallucination-Like Perception"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"The Brain Dopamine System in Opioid Use Disorder Recovery"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Epigenetic Reprogramming Alters Striatal Gene Responses in Cocaine Addiction"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Predicting Stress-Induced Anhedonia from Cortical Dynamics and Facial Expression"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Opioid Induced Plasticity and Behavior in Noradrenergic Systems"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Dopamine Mechanisms Underlying Cue-Elicited Compulsive Alcohol Seeking and Relapse"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Early Career Investigator Presentations
7:30 pm - 7:45 pm
Late-Breaking Topic
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Short Talk Selected from Poster Abstracts
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Short Talk Selected from Poster Abstracts
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Late-Breaking Topic
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Short Talk Selected from Poster Abstracts
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Catecholamine Systems, Synapses, and Neuromodulatory Mechanisms
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:25 am
"Distinguishing the Roles of Catecholamines Across Multiple Cognitive and Motivational Domains"
9:25 am - 9:35 am
Discussion
9:35 am - 9:55 am
"Corticonigral Projections Recruit Dopaminergic Neurons for Auditory Threat Learning"
9:55 am - 10:05 am
Discussion
10:05 am - 10:25 am
"Facilitating Striatal Plasticity with Salient Stimuli"
10:25 am - 10:35 am
Discussion
10:35 am - 11:10 am
Coffee Break
11:10 am - 11:30 am
"Evolving Views of a Special Relationship Between Neuromodulatory Neurons and the Integrated Stress Response"
11:30 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"Cortical-Basal Ganglia-Thalamocortical Circuits and Reinforcement Learning"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Catecholamines in Pain and Nociception
7:30 pm - 7:50 pm
"Dopamine at the Intersection of Alcohol and Pain"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"An Amygdala-Accumbens Axis for Aversion to Pain"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Dorsal Root Ganglion RGS4 Regulates Peripheral Nerve Injury-Associated Molecular and Behavioral Maladaptations in Murine Pain Models"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Endogenous Opioid Regulation of Locus Coeruleus-Mediated Analgesia"
9:20 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure