Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Diverse Roles for Catecholamines in Learning
3:45 pm - 3:55 pm
"Dynamics of Dopaminergic Transmission in the Prelimbic Cortex during Approach-Avoidance Conflict in Rats"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 4:10 pm
"VTA GABA Neurons Integrate Positive and Negative Valence"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
"Prefrontal Neuromodulators Perform Divergent Roles in Aversive Learning Through Cyclic AMP"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Catecholamine Dysfunction in Disease
7:30 pm - 7:45 pm
"Circadian Rhythms in Neural Mechanisms in the Nucleus Accumbens Underlying Substance Use Disorders"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
"Dopamine-Hypersensitive D1-Medium Spiny Neurons Linked to Increased cFos Expression Upon Cocaine Exposure"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
"Noradrenergic Modulation of Dopaminergic Neurons in the Dorsal Raphe Nucleus Contributes to Stress-Induced Reward Insensitivity"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
"Aging Impairs Dopamine-Glutamate Projections in the Lateral Entorhinal Cortex and Diminishes Memory Performance Which Is Rescued by Optogenetic Stimulation"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
"Creating Human Locus Coeruleus Organoids to Study the Role of the Locus Coeruleus in Alzheimer’s Disease"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
"Gene Expression in the Mid-Life Human Locus Coeruleus Across Alzheimer’s Risk Factors and Neuromelanin Content"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Models and Methods to Understand Catecholaminergic Structure and Function
9:00 am - 9:15 am
"Dopamine, Fast and Slow: Disentangling the Contributions of Natural Rewards and Optical Stimulation on Ventral Striatal Dopamine across Temporal Scales"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
"The Effects of Cocaine Delivery Rate on Drug-Conditioned Behavior and Neural Dynamics in the Nucleus Accumbens"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
"Molecular and Functional Characterization of Transcriptionally Defined Subpopulations of VTA Dopamine Neurons"
9:55 am - 10:00 am
Discussion
10:00 am - 10:15 am
"Utilizing Visual Stimuli to Promote Cell-Type Selective Accumbal Plasticity"
10:15 am - 10:20 am
Discussion
10:20 am - 10:35 am
"Organizational Features of the Locus Coeruleus-Norepinephrine Projection to Cerebellum in the Mouse"
10:35 am - 10:40 am
Discussion
10:40 am - 10:55 am
"Neural Circuit-Selective, Multiplexed Pharmacological Targeting of Prefrontal Cortex-Projecting Locus coeruleus Neurons Drives Antinociception"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Influence of Catecholamines on Feeding Behavior
1:30 pm - 1:45 pm
"Hedonic Eating is Controlled by Dopamine Neurons that Oppose GLP-1R Satiety"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
"A Brain Reward Circuit Inhibited By Next-Generation Weight Loss Drugs"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
"Locus Coeruleus Output Modulates Cortical Taste Encoding"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes
