Sunday 
 
 
4:00 pm - 8:00 pm 
	
Arrival and Check-in
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 7:40 pm 
	
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
 
 
						
7:40 pm - 9:30 pm 
	
 
 
						
7:40 pm - 7:45 pm 
	
Opening Remarks
 
 
						
7:45 pm - 8:10 pm 
	
"Meeting Your Quota: The Cellular Economy of Zinc" 
 
 
 
						
8:10 pm - 8:20 pm 
	
Discussion
 
 
						
8:20 pm - 8:45 pm 
	
"Mining Metalloproteome by Chemical and Computational Proteomics" 
 
 
 
						
8:45 pm - 8:55 pm 
	
Discussion
 
 
						
8:55 pm - 9:20 pm 
	
"Structural and Functional Characterization of Processes for Copper Transport and FeS Protein Biogenesis" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Monday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 12:30 pm 
	
Metals at the Host-Pathogen Interface 
 
 
 
						
9:00 am - 9:25 am 
	
"In Vitro  Reconstitution and Mechanistic Dissection of Iron Transport at the Host-Pathogen Interface for Legionella pneumophila " 
 
 
 
						
9:25 am - 9:35 am 
	
Discussion
 
 
						
9:35 am - 10:00 am 
	
"Vitamin B12 and Other Metal-Based Mechanisms in Bacterial Light Sensing and Signaling" 
 
 
 
						
10:00 am - 10:10 am 
	
Discussion
 
 
						
10:10 am - 10:35 am 
	
Coffee Break
 
 
						
10:35 am - 11:00 am 
	
"Feeding on the Host: How Do Human Fungal Pathogens Acquire Essential Trace Metals During Infection?" 
 
 
 
						
11:00 am - 11:10 am 
	
Discussion
 
 
						
11:10 am - 11:35 am 
	
"Iron Utilization by Malaria Parasites" 
 
 
 
						
11:35 am - 11:45 am 
	
Discussion
 
 
						
11:45 am - 11:55 am 
	
"Bacterial Adaptation to Manganese Starvation: A Tale of Two Enzymes" 
 
 
 
						
11:55 am - 12:00 pm 
	
Discussion
 
 
						
12:00 pm - 12:10 pm 
	
"Transcriptional and Translational Reprogramming in Response to Copper Status in the Pathogenic Fungus Cryptococcus neoformans " 
 
 
 
						
12:10 pm - 12:15 pm 
	
Discussion
 
 
						
12:15 pm - 12:30 pm 
	
Poster Previews
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:30 pm 
	
Free Time
 
 
						
4:30 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 8:00 pm 
	
Cellular Metal Sensation and Homeostasis 
 
 
 
						
6:00 pm - 6:25 pm 
	
"Molecular Mechanisms of Bacterial Metallostasis" 
 
 
 
						
6:25 pm - 6:35 pm 
	
Discussion
 
 
						
6:35 pm - 7:00 pm 
	
"Regulatory and Metabolic Responses to Iron Deficiency" 
 
 
 
						
7:00 pm - 7:10 pm 
	
Discussion
 
 
						
7:10 pm - 7:35 pm 
	
"Zinc Sensing and Signaling in C. elegans " 
 
 
 
						
7:35 pm - 7:45 pm 
	
Discussion
 
 
						
7:45 pm - 7:55 pm 
	
"Selective Recognition and Utilization of Lanthanides in Biology" 
 
 
 
						
7:55 pm - 8:00 pm 
	
Discussion
 
 
						
8:00 pm - 9:00 pm 
	
Dinner
 
 
						
	Tuesday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
8:30 am 
	
Group Photo
 
 
						
9:00 am - 12:30 pm 
	
 
 
						
9:00 am - 9:25 am 
	
"A Novel Liver/Gut/Microbiota Axis Control Iron Homeostasis" 
 
 
 
						
9:25 am - 9:35 am 
	
Discussion
 
 
						
9:35 am - 10:00 am 
	
"Serum and Tissue Iron Sensing by the Liver" 
 
 
 
						
10:00 am - 10:10 am 
	
Discussion
 
 
						
10:10 am - 10:35 am 
	
Coffee Break
 
 
						
10:35 am - 11:00 am 
	
"An Unexpected Role for Metal Transporters in Systemic Metabolism" 
 
 
 
						
11:00 am - 11:10 am 
	
Discussion
 
 
						
11:10 am - 11:35 am 
	
"Out-of-Balance: Pathophysiological Consequences of Iron Overload" 
 
 
 
						
11:35 am - 11:45 am 
	
Discussion
 
 
						
11:45 am - 11:55 am 
	
"Hepatic Bioenergetic Deficiency Induces a Novel Signal that Systemically Suppresses the Immune System" 
 
 
 
						
11:55 am - 12:00 pm 
	
Discussion
 
 
						
12:00 pm - 12:10 pm 
	
"Role of Zinc at Neuronal Nerve Terminals" 
 
 
 
						
12:10 pm - 12:15 pm 
	
Discussion
 
 
						
12:15 pm - 12:25 pm 
	
"Bile Acid Regulation of Intestinal Manganese Transport" 
 
 
 
						
12:25 pm - 12:30 pm 
	
Discussion
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:30 pm 
	
Free Time
 
 
						
4:30 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 8:00 pm 
	
Cellular Metal Partitioning 
 
 
 
						
6:00 pm - 6:25 pm 
	
"Ironing-out the Connection Between Mitochondria and Lysosomes" 
 
 
 
						
6:25 pm - 6:35 pm 
	
Discussion
 
 
						
6:35 pm - 7:00 pm 
	
"Mitochondrial Copper Transporter Modulates Targets Inside and Outside of Mitochondria" 
 
 
 
						
7:00 pm - 7:10 pm 
	
Discussion
 
 
						
7:10 pm - 7:35 pm 
	
"Handling Heme: Probing the Mechanisms Underlying Heme Trafficking and Utilization" 
 
 
 
						
7:35 pm - 7:45 pm 
	
Discussion
 
 
						
7:45 pm - 7:55 pm 
	
"Grab Regulates Endosomal Trafficking of The Transferrin Receptor in Developing Erythroblasts" 
 
 
 
						
7:55 pm - 8:00 pm 
	
Discussion
 
 
						
8:00 pm - 9:00 pm 
	
Dinner
 
 
						
	Wednesday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 12:30 pm 
	
 
 
						
9:00 am - 9:25 am 
	
"Molybdenum Cofactor Synthesis and Enzymes in Mitochondria" 
 
 
 
						
9:25 am - 9:35 am 
	
Discussion
 
 
						
9:35 am - 10:00 am 
	
"Enzymology of Heme Biosynthesis" 
 
 
 
						
10:00 am - 10:10 am 
	
Discussion
 
 
						
10:10 am - 10:35 am 
	
Coffee Break
 
 
						
10:35 am - 11:00 am 
	
"The Special Relationship Between Cobalt and the Corrin Ring of Vitamin B12" 
 
 
 
						
11:00 am - 11:10 am 
	
Discussion
 
 
						
11:10 am - 11:35 am 
	
"Unraveling the Complex(ity) of Heme Synthesis and Distribution" 
 
 
 
						
11:35 am - 11:45 am 
	
Discussion
 
 
						
11:45 am - 11:55 am 
	
"Understanding Cobalt Acquisition for Vitamin B12" 
 
 
 
						
11:55 am - 12:00 pm 
	
Discussion
 
 
						
12:00 pm - 12:10 pm 
	
"Structural Basis of Zinc-Dependent Protein Quality Control in the Early Secretory Pathway" 
 
 
 
						
12:10 pm - 12:15 pm 
	
Discussion
 
 
						
12:15 pm - 12:25 pm 
	
"Control of Heme Biosynthesis and Acquisition in Staphylococcus aureus " 
 
 
 
						
12:25 pm - 12:30 pm 
	
Discussion
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:30 pm 
	
Free Time
 
 
						
4:30 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 8:00 pm 
	
New Paradigms in Metal Metabolism 
 
 
 
						
6:00 pm - 6:25 pm 
	
"How Cells Import Copper and Cope with Copper Deficiency" 
 
 
 
						
6:25 pm - 6:35 pm 
	
Discussion
 
 
						
6:35 pm - 7:00 pm 
	
"Understanding Bacterial Metal Defense via Single-Molecule/Cell Microscopy" 
 
 
 
						
7:00 pm - 7:10 pm 
	
Discussion
 
 
						
7:10 pm - 7:35 pm 
	
"Zinc Regulation of the Mammalian Cell Cycle" 
 
 
 
						
7:35 pm - 7:45 pm 
	
Discussion
 
 
						
7:45 pm - 7:55 pm 
	
"Uncovering Essential Metal Interactions in the Gut Microbiota: A Study on Lactobacillus plantarum  and Zinc" 
 
 
 
						
7:55 pm - 8:00 pm 
	
Discussion
 
 
						
8:00 pm - 9:00 pm 
	
Dinner
 
 
						
	Thursday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
8:30 am - 9:00 am 
	
Business Meeting 
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair 
 
 
						
9:00 am - 12:30 pm 
	
Metals in Physiology and Disease 
 
 
 
						
9:00 am - 9:25 am 
	
"Cardiovascular Iron Homeostasis" 
 
 
 
						
9:25 am - 9:35 am 
	
Discussion
 
 
						
9:35 am - 10:00 am 
	
"Manganese Homeostasis and Induced-Parkinsonism: Insights from Studies of a Rare Genetic Disease" 
 
 
 
						
10:00 am - 10:10 am 
	
Discussion
 
 
						
10:10 am - 10:35 am 
	
Coffee Break
 
 
						
10:35 am - 11:00 am 
	
"Lessons from Porphyrias: Disproportion of Iron and Heme" 
 
 
 
						
11:00 am - 11:10 am 
	
Discussion
 
 
						
11:10 am - 11:35 am 
	
"Mechanisms of ATP7A-Related Copper Transport Diseases" 
 
 
 
						
11:35 am - 11:45 am 
	
Discussion
 
 
						
11:45 am - 11:55 am 
	
"Post-Transcriptional Regulation of Atp7a mRNA in Skeletal Muscle Myoblasts" 
 
 
 
						
11:55 am - 12:00 pm 
	
Discussion
 
 
						
12:00 pm - 12:10 pm 
	
"New Roles of Transcription Factor Spic in Inflammation and Iron Metabolism" 
 
 
 
						
12:10 pm - 12:15 pm 
	
Discussion
 
 
						
12:15 pm - 12:25 pm 
	
"Cadmium Accumulation in Insulin Producing Beta Cells in the Pathophysiology of Type 2 Diabetes" 
 
 
 
						
12:25 pm - 12:30 pm 
	
Discussion
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:30 pm 
	
Free Time
 
 
						
4:30 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 8:00 pm 
	
Keynote Session: Cellular Metal Compartmentalization and Regulation 
 
 
 
						
6:00 pm - 6:05 pm 
	
Introduction by Discussion Leader
 
 
						
6:05 pm - 6:45 pm 
	
"Metal Dynamics: From the Soil to the Seed" 
 
 
 
						
6:45 pm - 7:00 pm 
	
Discussion
 
 
						
7:00 pm - 7:05 pm 
	
Introduction by Discussion Leader
 
 
						
7:05 pm - 7:45 pm 
	
"Biogenesis of Iron-Sulfur Proteins in Eukaryotes: Mitochondria, Mitosomes, Mechanisms and Maladies" 
 
 
 
						
7:45 pm - 8:00 pm 
	
Discussion
 
 
						
8:00 pm - 9:00 pm 
	
Dinner
 
 
						
	Friday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am 
	
Departure