Sunday 
 
 
2:00 pm - 9:00 pm 
	
Arrival and Check-in
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 7:40 pm 
	
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
 
 
						
7:40 pm - 9:30 pm 
	
Metal Nutrition from Plants to Humans 
 
 
 
						
7:40 pm - 7:45 pm 
	
Introduction by Discussion Leader
 
 
						
7:45 pm - 8:10 pm 
	
"To Grow or to Defend? Iron at the Nexus of Root Response Programs" 
 
 
 
						
8:10 pm - 8:20 pm 
	
Discussion
 
 
						
8:20 pm - 8:45 pm 
	
"Vitamin B12: From Biofortification to Industrial Biotechnology" 
 
 
 
						
8:45 pm - 8:55 pm 
	
Discussion
 
 
						
8:55 pm - 9:20 pm 
	
"Uncovering Time-Dependent Iron-Related Phenotypes Using Dynamic Imaging and Computer Vision" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Monday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 12:30 pm 
	
Metals in Metabolic Disorders and Disease 
 
 
 
						
9:00 am - 9:25 am 
	
"Molecular and Cellular Mechanisms of Copper-Dependent Nutrient Signaling and Metabolism" 
 
 
 
						
9:25 am - 9:35 am 
	
Discussion
 
 
						
9:35 am - 10:00 am 
	
"Role of Manganese in Inflammatory Bowel Disease" 
 
 
 
						
10:00 am - 10:10 am 
	
Discussion
 
 
						
10:10 am - 10:40 am 
	
Coffee Break
 
 
						
10:40 am - 11:05 am 
	
"How Studies of Wilsons Disease Helped Discover New Tissue Specific Functions of ATP7B" 
 
 
 
						
11:05 am - 11:15 am 
	
Discussion
 
 
						
11:15 am - 11:40 am 
	
"The Ins and Outs of Heme Transport" 
 
 
 
						
11:40 am - 11:50 am 
	
Discussion
 
 
						
11:50 am - 12:00 pm 
	
"Role of Hepatic Hypoxia Inducible Factors in Inherited Disorder of Manganese Excess due to Slc30a10 Deficiency" 
 
 
 
						
12:00 pm - 12:05 pm 
	
Discussion
 
 
						
12:05 pm - 12:15 pm 
	
"Ironing Out the Details of Mitochondrial Translation" 
 
 
 
						
12:15 pm - 12:20 pm 
	
Discussion
 
 
						
12:20 pm - 12:30 pm 
	
Poster Previews
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
The Environmental Impact of Metals 
 
 
 
						
7:30 pm - 7:55 pm 
	
"Marine Microbial Metaproteomics: Small Engines, Global Cycles" 
 
 
 
						
7:55 pm - 8:05 pm 
	
Discussion
 
 
						
8:05 pm - 8:30 pm 
	
"New Principles in Biological Recognition of Lanthanides" 
 
 
 
						
8:30 pm - 8:40 pm 
	
Discussion
 
 
						
8:40 pm - 9:05 pm 
	
"A Molecular Window into the Black Box of Environmental Trace Metal Speciation" 
 
 
 
						
9:05 pm - 9:15 pm 
	
Discussion
 
 
						
9:15 pm - 9:25 pm 
	
"Characterization of a Novel Methanogen Radical SAM/SPASM Domain Enzyme" 
 
 
 
						
9:25 pm - 9:30 pm 
	
Discussion
 
 
						
	Tuesday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
8:30 am - 9:00 am 
	
Group Photo
 
 
						
9:00 am - 12:30 pm 
	
Metal Clusters, Cofactors and Catalysis 
 
 
 
						
9:00 am - 9:25 am 
	
"Glutathione at the Nexus of Iron and Redox Metabolism" 
 
 
 
						
9:25 am - 9:35 am 
	
Discussion
 
 
						
9:35 am - 10:00 am 
	
"Molybdenum Cofactor Transport and Metabolism in the Nematode C. elegans " 
 
 
 
						
10:00 am - 10:10 am 
	
Discussion
 
 
						
10:10 am - 10:35 am 
	
Coffee Break
 
 
						
10:35 am - 11:00 am 
	
"Metalloproteins in Chlorophyll Biosynthesis" 
 
 
 
						
11:00 am - 11:10 am 
	
Discussion
 
 
						
11:10 am - 11:35 am 
	
"Zinc-Dependent In-Cell Kinetic Stability of Metallo-beta-Lactamases is a Key Evolutionary Trait" 
 
 
 
						
11:35 am - 11:45 am 
	
Discussion
 
 
						
11:45 am - 11:55 am 
	
"Investigating the Biochemical Response of BTS-like Proteins" 
 
 
 
						
11:55 am - 12:00 pm 
	
Discussion
 
 
						
12:00 pm - 12:10 pm 
	
"Structural Consequences of Turnover-Induced Homocitrate Loss in Nitrogenase" 
 
 
 
						
12:10 pm - 12:15 pm 
	
Discussion
 
 
						
12:15 pm - 12:25 pm 
	
"Understanding Mis-metalation of Native Versus Heterologously Expressed Proteins" 
 
 
 
						
12:25 pm - 12:30 pm 
	
Discussion
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
Metal Homeostasis in Cell Death and Aging 
 
 
 
						
7:30 pm - 7:55 pm 
	
"Design and Therapeutic Applications of a Small Molecule Inhibitor of Copper Transporting P-type ATPases" 
 
 
 
						
7:55 pm - 8:05 pm 
	
Discussion
 
 
						
8:05 pm - 8:30 pm 
	
"Modulating Ferroptosis for Disease Prevention" 
 
 
 
						
8:30 pm - 8:40 pm 
	
Discussion
 
 
						
8:40 pm - 9:05 pm 
	
"Mechanisms Regulating Copper-Dependent Cell Death" 
 
 
 
						
9:05 pm - 9:15 pm 
	
Discussion
 
 
						
9:15 pm - 9:25 pm 
	
"Copper Homeostasis Regulates the Host Immune Response" 
 
 
 
						
9:25 pm - 9:30 pm 
	
Discussion
 
 
						
	Wednesday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 12:30 pm 
	
Metal Trafficking, Storage and Regulation 
 
 
 
						
9:00 am - 9:25 am 
	
"From Zn Chaperones to Novel Heme Coordination: Genome Mining Provides the Spark" 
 
 
 
						
9:25 am - 9:35 am 
	
Discussion
 
 
						
9:35 am - 10:00 am 
	
"Using the Circadian Clock to Uncover the Regulatory Role of Heme in Biology" 
 
 
 
						
10:00 am - 10:10 am 
	
Discussion
 
 
						
10:10 am - 10:40 am 
	
Coffee Break
 
 
						
10:40 am - 11:05 am 
	
"New Insights into Iron Transport in Mycobacterium tuberculosis " 
 
 
 
						
11:05 am - 11:15 am 
	
Discussion
 
 
						
11:15 am - 11:40 am 
	
"Balancing Copper Economy and Luxury through a Conserved Signaling Pathway" 
 
 
 
						
11:40 am - 11:50 am 
	
Discussion
 
 
						
11:50 am - 12:00 pm 
	
"Cation Diffusion Facilitator Proteins Mediate Mn Tolerance in C. elegans " 
 
 
 
						
12:00 pm - 12:05 pm 
	
Discussion
 
 
						
12:05 pm - 12:15 pm 
	
"Uncovering Heme Binding Sites with a Bioinformatics Approach" 
 
 
 
						
12:15 pm - 12:20 pm 
	
Discussion
 
 
						
12:20 pm - 12:30 pm 
	
Poster Previews
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
Metals and Developmental Biology 
 
 
 
						
7:30 pm - 7:55 pm 
	
"Lysosome-Related Organelles Contain an Expansion Compartment that Mediates Zinc Transporter Delivery and Promotes Zinc Homeostasis in C. Elegans " 
 
 
 
						
7:55 pm - 8:05 pm 
	
Discussion
 
 
						
8:05 pm - 8:30 pm 
	
"From Fishtank to Bedside: Zebrafish to Model Inherited Manganese Transporter Defects" 
 
 
 
						
8:30 pm - 8:40 pm 
	
Discussion
 
 
						
8:40 pm - 9:05 pm 
	
"The Kynurenine Pathway in Systemic Zinc Regulation" 
 
 
 
						
9:05 pm - 9:15 pm 
	
Discussion
 
 
						
9:15 pm - 9:25 pm 
	
"Copper-Driven Signaling and Transcriptional Responses" 
 
 
 
						
9:25 pm - 9:30 pm 
	
Discussion
 
 
						
	Thursday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
8:30 am - 9:00 am 
	
Business Meeting 
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s) 
 
 
						
9:00 am - 12:30 pm 
	
Metals at the Host Pathogen Interface 
 
 
 
						
9:00 am - 9:25 am 
	
"Metals, Secondary Metabolites, and the Variable Host Environment" 
 
 
 
						
9:25 am - 9:35 am 
	
Discussion
 
 
						
9:35 am - 10:00 am 
	
"Bacterial and Host Metallophores in Infection Pathogenesis" 
 
 
 
						
10:00 am - 10:10 am 
	
Discussion
 
 
						
10:10 am - 10:35 am 
	
Coffee Break
 
 
						
10:35 am - 11:00 am 
	
"Developing Small Molecule Probes to Perturb Iron Homeostasis" 
 
 
 
						
11:00 am - 11:10 am 
	
Discussion
 
 
						
11:10 am - 11:35 am 
	
"sRNA-Controlled Iron Homeostasis in Staphylococci" 
 
 
 
						
11:35 am - 11:45 am 
	
Discussion
 
 
						
11:45 am - 12:05 pm 
	
"Maintenance of Organismal and Cellular Homeostasis by an Ancient Zinc Metallochaperone" 
 
 
 
						
12:05 pm - 12:15 pm 
	
Discussion
 
 
						
12:15 pm - 12:25 pm 
	
"Bracing Bacillus for Copper Acquisition" 
 
 
 
						
12:25 pm - 12:30 pm 
	
Discussion
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
Keynote Session: Imaging Metal Trafficking, Signaling and Reactivity 
 
 
 
						
7:30 pm - 7:40 pm 
	
Introduction by Discussion Leader
 
 
						
7:40 pm - 8:20 pm 
	
"Transition Metal Signaling and Metalloallostery in the Brain and Beyond" 
 
 
 
						
8:20 pm - 8:35 pm 
	
Discussion
 
 
						
8:35 pm - 9:15 pm 
	
"Regulation of Cell Biology by Zinc" 
 
 
 
						
9:15 pm - 9:30 pm 
	
Discussion
 
 
						
	Friday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am 
	
Departure