| SATURDAY |
| 1:00 pm - 5:00 pm | Arrival and Check-in |
| 3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:45 pm - 4:30 pm | Keynote Session |
| Discussion Leader: Enrique Fuentes-Mattei (The University of Texas M. D. Anderson Cancer Center) |
| 3:45 pm - 4:25 pm | Andre Kleensang (Johns Hopkins Bloomberg School of Public Health; Thomas Hartung Group)
"Mapping the Human Toxome by '-omics' Data for new Regulatory Tools"
|
| 4:25 pm - 4:30 pm | Discussion |
| 4:30 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Genes - Environmental interactions: Environmental exposure and the toxicological mechanisms leading to diseases |
| Discussion Leader: Ruth Roberts (AstraZeneca) |
| 7:30 pm - 7:45 pm | Daniel J. Spade (Brown University)
"Assessing Antiandrogenic Effects of In Utero Exposure to Dibutyl Phthalate and Other Xenobiotics"
|
| 7:45 pm - 7:50 pm | Discussion |
| 7:50 pm - 8:05 pm | Kathryn Page (University of California, Berkley)
"Toxic Milk Leading To 'Mask' Phenotype in Hephaestin Knockout Mice"
|
| 8:05 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:25 pm | Fei Zhao (University of Georgia)
"Effects and mechanisms of multigenerational exposure to zearalenone, a mycotoxin, on female reproduction"
|
| 8:25 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:45 pm | Smitha Pillai (EAWAG: Swiss Federal Institute)
"Anchoring transcriptome and proteome responses to the physiological phenotype of Chlamydomonas reinhardtii upon exposure to silver"
|
| 8:45 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:05 pm | Tianfang Huang (University of Arizona)
"Arsenic disrupts TGF-Beta-2 activity and epithelial to mesenchymal transition"
|
| 9:05 pm - 9:10 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 11:00 am | Epigenetic Regulations as a Mechanism for Gene-Environment Interaction: Toxicological Implications |
| Discussion Leader: Jay I. Goodman (Michigan State University) |
| 9:00 am - 9:20 am | Diego E. Montoya-Durango (University of Louisville)
"Disruption of the Evolutionarily Conserved Role of LINE-1/Retinoblastoma Proteins in Chromatin Functions by Environmental Carcinogens Belonging to the Polycyclic Aromatic Hydrocarbons Family"
|
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Chris Faulk (University of Michigan)
"Epigenetic Variation and Physiological Changes Induced by Pb in Mice"
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| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:15 am | Jay I. Goodman (Michigan State University)
"An Integrated View of Epigenetic Regulation of Gene Expression: Implications for Safety Assessment"
|
| 10:15 am - 10:20 am | Discussion |
| 10:20 am - 10:30 am | Hands-on Experimental Epigenetic Discussion (Epigenetic In Toxicology - Case Studies)
"How would you evaluate the potential of a chemical to cause an adverse epigenetic alteration?"
- Diego E. Montoya-Durango (University of Louisville)
- Muna Nahar (University of Michigan)
- Chris Faulk (University of Michigan)
|
| 10:30 am - 11:00 am | Discussion |
| 11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Mentorship/Career Development Component: How to build effective curriculum vitae for industry, government or academia & Finding grants for early career scientists |
| Discussion Leaders/Speakers: Donna L. Vogel (Johns Hopkins Medical Institutions) and Carol Shreffler (NIEHS) |
| 2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
| 3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |
