|
Saturday
|
| 2:00 pm - 5:00 pm |
Arrival and Check-in
|
| 3:30 pm - 3:45 pm |
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
|
| 3:45 pm - 4:30 pm |
Keynote Session: Centromeres in Evolution
Discussion Leader: Dawn Carone (Swarthmore College, USA)
|
| 3:45 pm - 4:15 pm |
Harmit Malik (Fred Hutchinson Cancer Research Center, USA)
"Genetic Conflicts Shape Centromeres and Centromeric Proteins"
|
| 4:15 pm - 4:30 pm |
Discussion
|
| 4:30 pm - 6:00 pm |
Poster Session
|
| 6:00 pm - 7:00 pm |
Dinner
|
| 7:30 pm - 9:30 pm |
Unwrapping Epigenetics at the Centromere
Discussion Leader: Gary Karpen (Lawrence Berkeley National Laboratory, USA)
|
| 7:30 pm - 7:50 pm |
Jitendra Thakur (Fred Hutchinson Cancer Research Center, USA)
"Structural Variations of the Human Centromeric Chromatin Complex"
|
| 7:50 pm - 8:00 pm |
Discussion
|
| 8:00 pm - 8:20 pm |
Eftychia Kyriacou (Wellcome Trust Centre for Cell Biology, University of Edinburgh, United Kingdom)
"High-Resolution Mapping of Human Centromeric Proteins"
|
| 8:20 pm - 8:30 pm |
Discussion
|
| 8:30 pm - 8:50 pm |
Charles Day (Hormel Institute, University of Minnesota, USA)
"Histone H3.3 Ser31 Phosphorylation Is Required to Prevent Chromosome Instability"
|
| 8:50 pm - 9:00 pm |
Discussion
|
| 9:00 pm - 9:20 pm |
Arunika Das (University of Pennsylvania, USA)
"Mechanisms of Transmitting Centromere Identity Through the Germline"
|
| 9:20 pm - 9:30 pm |
Discussion
|
|
Sunday
|
| 7:30 am - 8:30 am |
Breakfast
|
| 9:00 am - 11:00 am |
Centromere and Kinetochore Dynamics / Mentorship Component: Challenges Facing Biomedical Research
Discussion Leaders: Sue Biggins (Fred Hutchinson Cancer Research Center, USA) and Michael Blower (Massachusetts General Hospital, USA)
|
| 9:00 am - 9:15 am |
Xue Su (University of Edinburgh, United Kingdom)
"SUMOylation Regulates the Metaphase-Anaphase Transition by Inactivating the Pericentromeric Signaling Hub"
|
| 9:15 am - 9:20 am |
Discussion
|
| 9:20 am - 9:35 am |
Grace Hamilton (University of Washington, USA)
"Building a Minimal Functional Kinetochore: From Microtubule to Centromere"
|
| 9:35 am - 9:40 am |
Discussion
|
| 9:40 am - 9:55 am |
Agata Zielinska (Max Planck Institute for Biophysical Chemistry, Germany)
"New Insights into Chromosome and Kinetochore Organization During Mammalian Meiosis"
|
| 9:55 am - 10:00 am |
Discussion
|
| 10:00 am - 11:00 am |
Panel Discussion
Challenges Facing Biomedical Research
-
Girija Goyal (ReFigure, USA)
-
Fanuel Muindi (Harvard University / The STEM Advocacy Institute, USA)
-
Sarah Mazzilli (Boston University, USA)
|
| 11:00 am - 12:30 pm |
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
|
| 12:30 pm - 1:30 pm |
Lunch
|
| 1:30 pm - 2:30 pm |
Emerging Concepts in Centromere Control
Discussion Leader: Daniel Foltz (Northwestern University, USA)
|
| 1:30 pm - 1:50 pm |
Carlos Perea (Massachusetts General Hospital, USA)
"Regulation of Centromere Transcription by the Cohesin Ring Complex"
|
| 1:50 pm - 2:00 pm |
Discussion
|
| 2:00 pm - 2:20 pm |
Srivarsha Rajshekar (Weill Cornell Graduate School of Medical Sciences, USA)
"Pericentromeric DNA Hypomethylation Elicits an Interferon Response in an Animal Model of ICF Syndrome"
|
| 2:20 pm - 2:30 pm |
Discussion
|
| 2:30 pm - 3:00 pm |
Evaluation Period
Fill in GRS Evaluation Forms
|
| 3:00 pm |
Seminar Concludes
|
