Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Advances in Peptide Chemistry
Discussion Leaders: Bimal Koirala (University of Nevada, Reno, USA) and Diedra Shorty (University of California, Davis, USA)
3:45 pm - 4:00 pm
Patrick Salveson (University of California, Irvine, USA)
"Switching the Oligomerization State of Aβ-Derived Peptides with Light"
4:00 pm - 4:10 pm
Discussion
4:10 pm - 4:25 pm
Alicia Mangubat-Medina (Rice University, USA)
"Photoreversible Backbone Modification of Natural Proteins for Controlling Folding and Activity"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Exploring the Biological Activities of Peptides
Discussion Leaders: Kelly George (University of Pittsburgh, USA) and Adam Kreutzer (University of California, Irvine, USA)
7:30 pm - 7:45 pm
James Checco (University of Illinois at Urbana-Champaign, USA)
"Exploring the Signaling of D-Amino Acid-Containing Neuropeptides"
7:45 pm - 7:55 pm
Discussion
7:55 pm - 8:10 pm
Chloe Mitchell (The Hospital for Sick Children, Canada)
"Peptide-Based Inhibitors of Bacterial Small Multidrug Resistance Efflux Pumps"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:35 pm
Katlyn Fleming (University of Minnesota, USA)
"Structure-Activity Relationship Studies of a Macrocyclic AGRP-Mimetic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-DPro] Yield Potent and Selective Melanocortin-4 Receptor Antagonists that Increase Food Intake"
8:35 pm - 8:45 pm
Discussion
8:45 pm - 9:00 pm
Nicholas Sawyer (New York University, USA)
"Hydrogen Bond Surrogate Beta-Hairpins to Inhibit Protein-Protein Interactions"
9:00 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Charlie Saunders (Imperial College London, United Kingdom)
"Developing a Peptide Probe for the Myosin-A: Myosin Tail Interacting Protein Interaction of Plasmodium falciparum "
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Emerging Applications of Peptides
Discussion Leaders: James Checco (University of Illinois at Urbana-Champaign, USA) and Theo Flack (Imperial College London, United Kingdom)
9:00 am - 9:15 am
Gaurav Bhardwaj (University of Washington, USA)
"Accurate Computational Design of Heterochiral Constrained Peptides"
9:15 am - 9:25 am
Discussion
9:25 am - 9:40 am
Erik Hernandez (Wyss Institute for Biologically Inspired Engineering, Harvard University, USA)
"Selective Modification Chemistries for Natural and Unnatural Side Chains for Emerging Single-Molecule Peptide Sequencing Technologies"
9:40 am - 9:50 am
Discussion
9:50 am - 10:05 am
Zsofia Lengyel (Syracuse University, USA)
"Copper-Containing Catalytic Amyloids Promote Phosphoester Hydrolysis and Tandem Reactions"
10:05 am - 10:15 am
Discussion
10:15 am - 10:30 am
Poulami Majumder (National Cancer Institute, NIH, USA)
"Injectable Nanocomposite Hydrogel for Long-Term microRNA Therapy in Mesothelioma"
10:30 am - 10:40 am
Discussion
10:40 am - 10:55 am
Naomi Robertson (University of Cambridge, United Kingdom)
"A Two-Component Approach to Peptide Stapling"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Career Panel
Discussion Leaders: Cody Lensing (University of Minnesota, USA) and Marlies Hager (Unviersity of Illinois at Urbana-Champaign, USA)
1:30 pm - 2:30 pm
Panel Discussion
A Discussion of Career Paths
Wendy Hartsock (Ferring Research Institute, USA)
Yftah Tal-Gan (University of Nevada, Reno, USA)
Laura Kiessling (Massachusetts Institute of Technology, USA)
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
