Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: Forces in Craniofacial Biology
7:40 pm - 7:50 pm
Opening Remarks
7:50 pm - 8:25 pm
"Deducing the Influence of Mechanical Loads on Jaw Morphology"
8:25 pm - 8:40 pm
Discussion
8:40 pm - 9:15 pm
"Patterning Epithelia Through Mechanical and Turing Instabilities"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Signalling in Craniofacial Development
9:00 am - 9:25 am
"Cranial Suture Regeneration and Restored Neurocognitive Function in Craniosynostosis"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Psychology of Craniofacial Development"
10:00 am - 10:10 am
Discussion
10:10 am - 10:25 am
"Synergistic Role of GATA3 and Retinoic Acid Signaling in Primitive Choanae Development"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
"Skeletal Stem Cells Powering Cranial Suture Fate: An Answer to Craniosynostosis?"
11:25 am - 11:35 am
Discussion
11:35 am - 12:00 pm
"FGF Signaling in Development of the Cranial Vault"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Endochondral Ossification Requires Protein-Protein Interactions Between Prickle1 and Dishevelled 2/3"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Tissue Interactions and Morphogenesis
6:00 pm - 6:25 pm
"Gli Synergizes with Hand2 to Drive a Motif-Dependent Transcriptional Program During Mandibular Development"
6:25 pm - 6:35 pm
Discussion
6:35 pm - 7:00 pm
"Endodermal/Ectodermal Interfaces During Pharyngeal Segmentation"
7:00 pm - 7:10 pm
Discussion
7:10 pm - 7:20 pm
"Genetic Screening for Ethanol-Sensitive Zebrafish Mutants Identifies a Requirement for Bmp Signaling in Endoderm and Jaw Development"
7:20 pm - 7:25 pm
Discussion
7:25 pm - 7:40 pm
"Casting Light on Early Craniofacial Development Using Single Cell Transcriptome Analysis"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Hippo-Signaling in Cranial Neural Crest Development"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
9:00 am - 9:25 am
"Drug Based Modulation of Endogenous Fibrocartilage Stem Cells for TMJ Regeneration"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"The Use of Protein-Engineering to Create Biomaterials for 3D Printing and Stem Cell Expansion"
10:00 am - 10:10 am
Discussion
10:10 am - 10:25 am
"Robust Regeneration of Ligaments Supporting the Adult Zebrafish Jaw Joint"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:15 am
"Dissecting MSC Dynamics in a Regenerative Model Using Single Cell RNAseq"
11:15 am - 11:20 am
Discussion
11:20 am - 11:35 am
"Modulating an Extracellular Matrix-Inspired Skull Regenerative Material with Osteoprotegerin"
11:35 am - 11:40 am
Discussion
11:40 am - 11:55 am
"Distraction of the Calvarial Suture Niche Sustains Full Regeneration of a Remote Calvarial Critical Size Bone Defect"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Evolution and Comparative Biology of the Craniofacial Complex
6:00 pm - 6:25 pm
"Craniofacial Evo-Devo: Insights from Bony Fishes"
6:25 pm - 6:35 pm
Discussion
6:35 pm - 6:50 pm
"Salamander External Gill as a Craniofacial Model to Test the Paradigm of Patterned Body Appendages"
6:50 pm - 6:55 pm
Discussion
6:55 pm - 7:10 pm
"Do Cellular Stress Resistance Mechanisms Underlie Mammalian Regenerative Ability?"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:30 pm
"Dual Embryonic Origin of the Jawed Vertebrate Gill Arch Skeleton and the Evolutionary Origin of Paired Fins"
7:30 pm - 7:40 pm
Discussion
7:40 pm - 7:55 pm
"Genetic and Developmental Mechanisms of Craniofacial Variation in Domestic Pigeons"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Sense Organs and Cranial Neural Crest
9:00 am - 9:25 am
"Diversification of Neural Crest Derivatives in the Zebrafish Head"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Cellular Dynamics in the Ear"
10:00 am - 10:10 am
Discussion
10:10 am - 10:25 am
"Distinct and Cooperative Roles of SOX9 and SOX10 in Different Compartments of the Inner Ear Are Essential for Fluid Homeostasis and Hearing"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
"Dissecting the Formation and Maintenance of the Neural Crest Stem Cell Niche"
11:25 am - 11:35 am
Discussion
11:35 am - 11:50 am
"Visualizing the Dynamic Interplay Between the Mesoderm and Neural Crest During Chick Head Morphogenesis"
11:50 am - 11:55 am
Discussion
11:55 am - 12:10 pm
"Identification of Novel Candidate Genes Associated with SIX1 and Branchio-Oto-Renal Syndrome"
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
"Retention of Stem Cell Potential in the Neural Crest Is Mediated Through a Shared SoxB1 and SoxE Pluripotency GRN"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
6:00 pm - 6:25 pm
"New Approaches to Identifying NSCLP Genetic Variation"
6:25 pm - 6:35 pm
Discussion
6:35 pm - 7:00 pm
"Functional Analysis of IRF6 Target Genes in Craniofacial Development"
7:00 pm - 7:10 pm
Discussion
7:10 pm - 7:35 pm
7:35 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Uncovering the Genome-Wide Contribution of De Novo Mutations in Orofacial Clefts"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
9:00 am - 9:25 am
"ECM Trafficking Block Causes Craniofacial CATIFA Syndrome"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
"Cellular Mechanisms of Craniosynostosis in Saethre-Chotzen Syndrome"
10:00 am - 10:10 am
Discussion
10:10 am - 10:25 am
"Elucidating Candidate Genes that Modify Susceptibility to Alcohol-Induced Craniofacial Dysmorphology"
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:25 am
"The Power of the Face: Restoring Function Following Paralysis and Clefting"
11:25 am - 11:35 am
Discussion
11:35 am - 12:00 pm
"Grainyhead-Like (Grhl)-Dependent Pathways in Palatal Clefting"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
"Towards a Single Cell Transcriptomic Atlas of the Coronal Suture"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Cell and Tissue Mechanics
6:00 pm - 6:15 pm
"Mechanical Cues of Polyrotaxanes Control Osteogenic Differentiation for Adjunct Treatment of Craniosynostosis"
6:15 pm - 6:20 pm
Discussion
6:20 pm - 6:30 pm
"Dentin Structure Is Determined by Presence or Absence of Enamel"
6:30 pm - 6:35 pm
Discussion
6:35 pm - 7:00 pm
"Collective Cell Motion in Embryogenesis and Regeneration"
7:00 pm - 7:10 pm
Discussion
7:10 pm - 7:20 pm
"Investigating GSK3 in Mouse Cranial Neural Crest Cell Delamination and Early Migration using Live In Vivo Imaging"
7:20 pm - 7:25 pm
Discussion
7:25 pm - 7:50 pm
"Biomechanics of Calvarial Development"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure