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Crystals
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Discussion leader: Wayne Anderson
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Randy Read
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Welcome and introduction |
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Fred Dyda
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Iterative use of site directed mutagenesis to facilitate crystallization:
experiences with integrases |
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Jürg Rosenbusch
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Perspectives in the crystallization of membrane proteins |
| Joanne Yeh |
A flash annealing technique to improve diffraction limits and lower mosaicity in crystals of glycerol kinase |
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Pushing the limits of data
collection
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Discussion leader: Andrew Leslie
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Michael
Garavito
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Multilayer focusing mirrors for the X-ray laboratory: an exciting
new development? |
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Steve Ginell
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Cryocrystallography on extremely bright sources |
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Gerd Rosenbaum
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Third generation undulator synchrotron sources are a crystallographer's
heaven. Is there more life beyond heaven? |
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Robert
Sweet
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Progress in remote operation of synchrotron beamlines: approaching
the FedEx model of data collection |
| Marc Whitlow |
Comparison of area detectors |
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Crystallography and genomics
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Discussion leader: Tom Terwilliger
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Sung-Hou Kim
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Structural genomics: a pilot project |
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Andrej Sali
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Comparative protein structure modeling in genomics |
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John Moult
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Deducing function from structure |
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Adventures in phasing I
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Discussion leader: Bart Hazes
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Tom Terwilliger
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SOLVE: Automated MAD/MIR phasing |
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Janet Smith
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MAD phasing with large numbers of anomalous scatterers |
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Jan Pieter Abrahams
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The gamma correction beyond solvent flattening: perspectives of bias-free
refinement |
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Lynn Ten Eyck
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Eigenvalue filtering of the full matrix |
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Adventures in phasing II
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Discussion leader: Michael Chapman
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| Stephen Sheriff |
Implementation of a six-dimensional search using the AMoRe translation function for difficult molecular replacement problems |
| Paul Adams |
Extending the limits of molecular replacement through combined simulated annealing and maximum likelihood refinement |
| David Smith |
Finding many Se-Met sits with SnB |
| Abelardo Silva |
A continuous diffraction intensity function and its implications for phase determination |
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New tools for fitting and
refinement
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Discussion leader: Titia Sixma
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| Axel Brünger |
Crystallography and NMR System: A highly automated and flexible approach
to MAD/MIR/MR phasing and refinement |
| Navraj Pannu |
Recent advances in maximum likelihood structure refinement |
| Anastassis Perrakis |
wARP: automated procedures for density modification, phase extension and model building |
| Tom Oldfield |
Automated electron density tracing and fitting |
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Beyond single crystal X-ray
diffraction
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Discussion leader: Janet Smith |
| Andrew Leslie |
An application of cryo-electron microscopy imaging to X-ray structure
determination: The 3.6A resolution structure solution of Hepatitis B virus
core particle |
| Michael
Wall |
Making sense of diffuse scattering and making use of all the X-rays |
| Gerald
Stubbs |
Refinement in macromolecular fiber diffraction: lessons from
the filamentous viruses |
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Extreme crystallography
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Discussion leader: Jan Pieter Abrahams |
| Rick Bott |
Pushing back the envelope of resolution, and what you see when you do |
|
Elizabeth Getzoff |
Time-resolved crystallography |
| Nenad Ban |
A 9Å resolution X-ray crystallographis map of the large ribosomal subunit |
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Modeling and analysis
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Discussion leader: Jan Pieter Abrahams
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| Amy Anderson |
Targeting HIV opportunistic infections using rational drug design |
| Jonathan Friedman |
Computational prediction and experimental verification of unanticipated physiological ligands for proteins |
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Keynote address
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| Randy Read & Andrew Howard, Chairs |
Business meeting |
| Michael Rossmann |
The next era in structural biology |