Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: The Life Cycle of the Endothelium
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:10 pm
"Genetic Compensation in Endothelial Health and Disease"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:40 pm
"Endothelial Plasticity and Resilience Across Stress Responses and Aging"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:10 pm
"Endothelial Death Pathways Regulating Microvascular Hemostasis"
9:10 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Endothelial Cell Biology and Developmental Mechanisms
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Functional Roles for glycoRNAs in the Regulation of Endothelial Cells and Angiogenesis"
9:30 am - 9:40 am
Discussion
9:40 am - 9:55 am
Short Talk Selected from Poster Abstracts
9:55 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Novel Roles for Endomucin, An Endothelial Glycocalyx Component, in Inflammation and Angiogenesis"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Integrin-Independent Tie2 Activation Using de Novo Designed Proteins"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Degrading to Re-Grow: Harnessing Targeted Protein Degradation to Understand Principles of Vascular Development"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"The Social Life of Endothelial Cells: Tissue-Specific Interactions in Health and Disease"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Organ-Specific Endothelium
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:30 pm
"Molecular Heterogeneity and Functional Specialization of Endothelial Cells"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:00 pm
"Pulmonary, Bronchial, and Lymphatic Vascular Remodeling in Pulmonary Hypertension"
7:00 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Short Talk Selected from Poster Abstracts
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Distinctive Features and Specialized Physiology of Brain Endothelial Cells"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Endothelial Heterogeneity and Resilience
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Cadherin-6 (Cdh6) -Dependent Endohtelial Cell Adhesion in Endocardium and Lymphatics of Zebrfish"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
"From Force to Form: Integrins and Piezo1 Orchestrate Angiopoetin Signaling in the Vasculature"
10:00 am - 10:10 am
Discussion
10:10 am - 10:25 am
Short Talk Selected from Poster Abstracts
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Defining the Vascular Niche of Human Adipose Tissue Across Metabolic States"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Development of Angiocrine-Based First-in-Class Therapeutics for Organ Fibrosis"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
Late-Breaking Topic
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Technologies in Endothelial Research
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:30 pm
"Unveiling the Mysteries of Vascular Development and Regeneration with Advanced Human Organoid Models"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:00 pm
"Engineered Vasculature to Probe Endothelial Mechanoregulation"
7:00 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Short Talk Selected from Poster Abstracts
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Spatial Multiomics to Dissect Mechanisms of Kidney and Heart Disease"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Acute Diseases and Endothelial Pathophysiology
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Mechanisms and Treatment of Vascular Complications of Preeclampsia"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
"Novel Approaches to Preserve Blood Brain Barrier Integrity and Promote Angiogenesis in Stroke"
10:00 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:00 am
"Endothelial Mechanisms of Cognitive Dysfunction: Insights from Sepsis and Stroke"
11:00 am - 11:10 am
Discussion
11:10 am - 11:30 am
"Building and Breaking Barriers: 3D Blood-Brain Barrier Models for Cerebral Malaria Research"
11:30 am - 11:40 am
Discussion
11:40 am - 12:00 pm
"Not All Clotting is Blood Clotting: Biology and Disease of Lymphothrombosis"
12:00 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Chronic Diseases and Endothelial Pathophysiology
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:30 pm
"Endothelial Mechanisms of Obesity Associated Diabetes"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:00 pm
"Endothelial Immune Signaling in the Regulation of Cardiac Remodeling and Function"
7:00 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Short Talk Selected from Poster Abstracts
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Lymphatic Endothelium in Inflammation and Chronic Disease"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Endothelial Cells in Oncology and Immunology
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Blood Vessels and Cancer Therapy"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
"The Vasculature as a Target for Therapy in Glioblastoma"
10:00 am - 10:10 am
Discussion
10:10 am - 10:25 am
Short Talk Selected from Poster Abstracts
10:25 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Serendipity in Science: From a Surprising Observation to a Therapeutic Antibody"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Mechanisms of Endothelial Dysfunction in Systemic Autoimmune Diseases"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
Late-Breaking Topic
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Keynote Session: Entrepreneurial Endothelial Science
6:00 pm - 6:10 pm
Introduction by Discussion Leader
6:10 pm - 6:30 pm
"Endothelial Cell Research Driving Biotech Drug Discovery"
6:30 pm - 6:40 pm
Discussion
6:40 pm - 7:00 pm
"From Bench To Biotech in Retinal Vascular Disease"
7:00 pm - 7:10 pm
Discussion
7:10 pm - 7:25 pm
Short Talk Selected from Poster Abstracts
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Molecular Determinants of Tissue-Specific Endothelial Cells for Building Vascularized Mini-Organs"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure