Sunday 
 
 
2:00 pm - 9:00 pm 
	
Arrival and Check-in
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 7:40 pm 
	
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
 
 
						
7:40 pm - 9:30 pm 
	
 
 
						
7:40 pm - 7:50 pm 
	
Opening Remarks
 
 
						
7:50 pm - 8:10 pm 
	
"3D Folding and Enhancer Function" 
 
 
 
						
8:10 pm - 8:20 pm 
	
Discussion
 
 
						
8:20 pm - 8:40 pm 
	
"Two Mechanisms of Nuclear Organization" 
 
 
 
						
8:40 pm - 8:50 pm 
	
Discussion
 
 
						
8:50 pm - 9:05 pm 
	
"A Condensate Model for Gene Activity and Genome Organization" 
 
 
 
						
9:05 pm - 9:10 pm 
	
Discussion
 
 
						
9:10 pm - 9:25 pm 
	
"Single-Molecule Nanoscopy Elucidates RNA Polymerase II Transcription, Epigenetic Regulation and Genome Organization at Single Genes in Live Cells" 
 
 
 
						
9:25 pm - 9:30 pm 
	
Discussion
 
 
						
	Monday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
8:30 am - 9:00 am 
	
Group Photo
 
 
						
9:00 am - 12:30 pm 
	
Transposable Elements and Epigenome Evolution 
 
 
 
						
9:00 am - 9:05 am 
	
Introduction by Discussion Leader
 
 
						
9:05 am - 9:25 am 
	
"Avoiding Replication and Transcriptional Collisions by Repressing Repeats and Forming Nuclear Foci" 
 
 
 
						
9:25 am - 9:35 am 
	
Discussion
 
 
						
9:35 am - 9:55 am 
	
"How TEs and Their Krab-ZFP Controllers Shape Human-Specific Transcription Networks" 
 
 
 
						
9:55 am - 10:05 am 
	
Discussion
 
 
						
10:05 am - 10:20 am 
	
"pUG-Tailed RNAs Drive Gene Silencing and Transgenerational Epigenetic Inheritance" 
 
 
 
						
10:20 am - 10:25 am 
	
Discussion
 
 
						
10:25 am - 10:55 am 
	
Coffee Break
 
 
						
10:55 am - 11:15 am 
	
"Functional Evaluation of Transposable Elements as Enhancers in Mouse and Human Trophoblast" 
 
 
 
						
11:15 am - 11:25 am 
	
Discussion
 
 
						
11:25 am - 11:40 am 
	
"Control of Non-Coding RNA Production and Histone Levels by a 5'tRNA Fragment" 
 
 
 
						
11:40 am - 11:45 am 
	
Discussion
 
 
						
11:45 am - 12:05 pm 
	
"Using Metatherians to Elucidate the Evolution of Mammalian Epigenetic Pathways" 
 
 
 
						
12:05 pm - 12:15 pm 
	
Discussion
 
 
						
12:15 pm - 12:30 pm 
	
Poster Previews
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
RNA-Mediated Epi-Regulation 
 
 
 
						
7:30 pm - 7:50 pm 
	
"Small RNAs and Dosage Interactions in Plants" 
 
 
 
						
7:50 pm - 8:00 pm 
	
Discussion
 
 
						
8:00 pm - 8:20 pm 
	
"Epigenetic Gene Regulation in Arabidopsis " 
 
 
 
						
8:20 pm - 8:30 pm 
	
Discussion
 
 
						
8:30 pm - 8:50 pm 
	
"Sexually Dimorphic Expression of piRNAs in C. elegans " 
 
 
 
						
8:50 pm - 9:00 pm 
	
Discussion
 
 
						
9:00 pm - 9:20 pm 
	
"Paternal Contributions to Offspring Health: Intergenerational Epigenetic Inheritance via Sperm Small RNAs" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Tuesday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 12:30 pm 
	
Programming Future Generations 
 
 
 
						
9:00 am - 9:05 am 
	
Introduction by Discussion Leader
 
 
						
9:05 am - 9:25 am 
	
"Remembering the Past: A New Form of Protein-Based Epigenetics" 
 
 
 
						
9:25 am - 9:35 am 
	
Discussion
 
 
						
9:35 am - 9:55 am 
	
"Molecular Principles of Developmental Reprogramming and Gametogenesis" 
 
 
 
						
9:55 am - 10:05 am 
	
Discussion
 
 
						
10:05 am - 10:25 am 
	
"Heterochromatin Establishment by the Chromatin Remodeling Factor DDM1 in Arabidopsis " 
 
 
 
						
10:25 am - 10:35 am 
	
Discussion
 
 
						
10:35 am - 11:05 am 
	
Coffee Break
 
 
						
11:05 am - 11:25 am 
	
"Principles of Nucleosome Phasing Revealed by Genome-Wide Mapping and In Vitro  Reconstitution" 
 
 
 
						
11:25 am - 11:35 am 
	
Discussion
 
 
						
11:35 am - 11:50 am 
	
"The C. elegans  MES Chromatin Regulators Ensure Germline Survival by Repressing the X Chromosomes" 
 
 
 
						
11:50 am - 11:55 am 
	
Discussion
 
 
						
11:55 am - 12:10 pm 
	
"SPR-5; MET-2 Maternal Reprogramming Antagonizes H3K36me3 in the Control of Germline Versus Soma" 
 
 
 
						
12:10 pm - 12:15 pm 
	
Discussion
 
 
						
12:15 pm - 12:30 pm 
	
Poster Previews
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
Reprogramming During Development 
 
 
 
						
7:30 pm - 7:50 pm 
	
"Programmed DNA Elimination: Silencing Germline-Expressed Genes" 
 
 
 
						
7:50 pm - 8:00 pm 
	
Discussion
 
 
						
8:00 pm - 8:20 pm 
	
"Epigenetic Inheritance and Reprogramming in Early Mammalian Development" 
 
 
 
						
8:20 pm - 8:30 pm 
	
Discussion
 
 
						
8:30 pm - 8:50 pm 
	
"Establishment and Maintenance of Specialized Chromatin Domains" 
 
 
 
						
8:50 pm - 9:00 pm 
	
Discussion
 
 
						
9:00 pm - 9:20 pm 
	
"Distinct Architectures of Germ Line and Somatically Expressed Genes" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Wednesday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 12:30 pm 
	
Epigenetic Memory and Maintenance 
 
 
 
						
9:00 am - 9:20 am 
	
"Epigenetic Control of Programmed Genome Rearrangements in Paramecium " 
 
 
 
						
9:20 am - 9:30 am 
	
Discussion
 
 
						
9:30 am - 9:50 am 
	
"Domestication of Transposable Elements for Plant Reproduction" 
 
 
 
						
9:50 am - 10:00 am 
	
Discussion
 
 
						
10:00 am - 10:20 am 
	
"Control of Convergently Transcribed Genes Through Modulating Gene-Body Chromatin Modifications" 
 
 
 
						
10:20 am - 10:30 am 
	
Discussion
 
 
						
10:30 am - 11:00 am 
	
Coffee Break
 
 
						
11:00 am - 11:15 am 
	
"Super-Enhancer Switching Drives a Burst in Germline Gene Expression at the Mitosis-to-Meiosis Transition" 
 
 
 
						
11:15 am - 11:20 am 
	
Discussion
 
 
						
11:20 am - 11:35 am 
	
"Biased Fork Movement Coupled with Strand-Specific Histone Incorporation Ensures Asymmetric Histone Inheritance" 
 
 
 
						
11:35 am - 11:40 am 
	
Discussion
 
 
						
11:40 am - 11:55 am 
	
"Epigenetic Inheritance Independent of Asymmetric Histone Inheritance" 
 
 
 
						
11:55 am - 12:00 pm 
	
Discussion
 
 
						
12:00 pm - 12:20 pm 
	
"Regulation of Differentiation by Novel Chromatin Remodelers and Promoters" 
 
 
 
						
12:20 pm - 12:30 pm 
	
Discussion
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:00 pm - 7:30 pm 
	
Business Meeting 
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair 
 
 
						
7:30 pm - 9:30 pm 
	
Biophysics and Mathematical Models 
 
 
 
						
7:30 pm - 7:50 pm 
	
"Polymer Physics Predicts the Impact of Structural Variants on Chromatin 3D Architecture" 
 
 
 
						
7:50 pm - 8:00 pm 
	
Discussion
 
 
						
8:00 pm - 8:20 pm 
	
"Modeling Polycomb-Mediated Epigenetic Silencing" 
 
 
 
						
8:20 pm - 8:30 pm 
	
Discussion
 
 
						
8:30 pm - 8:50 pm 
	
"Kinetics of DNA Maintenance Methylation at Single Molecule Level and Underlying Mechanisms" 
 
 
 
						
8:50 pm - 9:00 pm 
	
Discussion
 
 
						
9:00 pm - 9:20 pm 
	
"3D Chromatin Organization and Gene Regulation" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Thursday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 12:30 pm 
	
 
 
						
9:00 am - 9:20 am 
	
"Antisense-Mediated Chromatin Regulation" 
 
 
 
						
9:20 am - 9:30 am 
	
Discussion
 
 
						
9:30 am - 9:50 am 
	
"Epigenetic Regulation of Sex Determination" 
 
 
 
						
9:50 am - 10:00 am 
	
Discussion
 
 
						
10:00 am - 10:20 am 
	
"Cellular Heterogeneity in Circadian Oscillation Driven by DNA Methylation and Transcriptional Noise" 
 
 
 
						
10:20 am - 10:30 am 
	
Discussion
 
 
						
10:30 am - 11:00 am 
	
Coffee Break
 
 
						
11:00 am - 11:20 am 
	
"A Role for Epigenetic Reprogramming During Meiosis in Plants" 
 
 
 
						
11:20 am - 11:30 am 
	
Discussion
 
 
						
11:30 am - 11:50 am 
	
"H3.3K27M-Induced Chromatin Changes Drive Ectopic Replication Through Misregulation of the JNK Pathway" 
 
 
 
						
11:50 am - 12:00 pm 
	
Discussion
 
 
						
12:00 pm - 12:20 pm 
	
"Phosphorylation of Histone H3.3 at Serine 31 Promotes p300 Activity" 
 
 
 
						
12:20 pm - 12:30 pm 
	
Discussion
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
Genome Function and Disease 
 
 
 
						
7:30 pm - 7:50 pm 
	
"Unexpected Contributors to the Establishment of X Inactivation" 
 
 
 
						
7:50 pm - 8:00 pm 
	
Discussion
 
 
						
8:00 pm - 8:20 pm 
	
"(Epi)genetic Control of Phenotypic Variation and Disease Heterogeneity" 
 
 
 
						
8:20 pm - 8:30 pm 
	
Discussion
 
 
						
8:30 pm - 8:50 pm 
	
"Mechanisms of Transgenerational Epigenetic Inheritance" 
 
 
 
						
8:50 pm - 9:00 pm 
	
Discussion
 
 
						
9:00 pm - 9:20 pm 
	
"Key Role for HUSH in Triplet-Repeat Silencing in Disease?" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Friday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am 
	
Departure