Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Visualizing Interactions in Epithelial Homeostasis and Disease
7:40 pm - 8:20 pm
"Using Advanced Dynamic and Multiplex Static Imaging to Understand Tissue Organization and Function"
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
"Therapeutic and Genetic Approaches to Alopecia Areata and Skin Blistering Diseases"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Homeostatic Growth and Regeneration of Epithelia: Novel Concepts in Cell Death and Renewal
9:00 am - 9:20 am
"Plasticity and Epithelial Regeneration"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Clonal Competition in Squamous Carcinogenesis"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:50 am
"Cellular Reprogramming by Defined Factors Drives Tissue Repair Following Injury of the Intestinal Epithelium"
10:50 am - 11:00 am
Discussion
11:00 am - 11:10 am
"Eye to Eye: Visualizing Stem Cell Activity and Regeneration of the Live Corneal Epithelium"
11:10 am - 11:15 am
Discussion
11:15 am - 11:25 am
"Diverse Roles of Polycomb Repressive Complexes in Epidermal Stem Cell Maintenance and Differentiation"
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
"The Mitophagy Receptor NIX Is Unregulated During Epidermal Differentiation and Drives Mitochondrial Fragmentation via Drp1"
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Single Cell RNA-Seq Reveals a Novel Cell Type in Airway Epithelium"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Distinct Functions for Class I HDACs in Epithelial Progenitor Cell Self-Renewal and Differentiation"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Evolution and Morphogenesis of Skin and Its Appendages
6:00 pm - 6:20 pm
"The Development and Evolution of Colour Patterns in Fishes"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
"Diversification of Epidermal Differentiation Proteins During the Evolution of the Skin in Mammals, Reptiles and Birds"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 7:05 pm
"Evo-Devo of Skin Stem Cells and Their Regulation"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"Hox Demarcates Regional Regeneration of Skin"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Chromatin Dynamics During Epithelial Commitment"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Cancerous Growth, Migration and Invasion of Epithelia
9:00 am - 9:20 am
"Plasticity of Collective Invasion in Epithelial and Mesenchymal Cancer Cells"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Skin Stem Cells and Their Niche Interactions in Homeostasis and Cancer"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:50 am
"Target Genes and Target Cells in Skin Cancer"
10:50 am - 11:00 am
Discussion
11:00 am - 11:10 am
"Live Imaging of Coordinated Epidermal Stem Cell Differentiation and Self-Renewal in Mice"
11:10 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Molecular Basis of Merkel Cell Carcinoma"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Chromatin Architectural Protein CTCF Controls Epidermal Barrier Formation, Hair Follicle Cell Fate Maintenance and Suppresses Inflammatory Responses in the Epithelium of Developing and Adult Skin"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Cancer Cell of Origin, Multipotency and Tumor Heterogeneity in the Mammary Gland"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Genetic and Epigenetic Determinants of Cell Fate
6:00 pm - 6:20 pm
"Distinguishing Plasticity from Fate During Intestinal Self Renewal"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:50 pm
"New RNA and Protein Regulators of Ras Signaling"
6:50 pm - 7:00 pm
Discussion
7:00 pm - 7:10 pm
"Emerging Roles of Hair Follicles' Transit Amplifying Cells in skin Development and Regeneration"
7:10 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"Dermal Adipocyte Lipolysis Is Required for Multiple Aspects of Skin Regeneration"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Genetic and Epigenetic Regulation of Skin Epithelial Stem Cell Lineages in and out of Their Niches"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Advances in Cell- and Tissue-Architecture Control
9:00 am - 9:20 am
"Imaging Healthy and Malignant Hematopoiesis: Active Cells in a Dynamic Environment"
9:20 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Cadherins Are Key Determinants of Epidermal Polarity and Tension"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"NuMA:LGN Hetero-Hexamers Cluster Active Dynein Motors at the Cortex to Promote Planar Cell Divisions"
9:55 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:50 am
"Biomechanics of Stem Cell Fate Regulation"
10:50 am - 11:00 am
Discussion
11:00 am - 11:10 am
"Rugged Terrain: The Search for Oral Epithelial Stem Cells"
11:10 am - 11:15 am
Discussion
11:15 am - 11:35 am
"Interplay Between Intermediate Filaments and Redox Balance in Disease"
11:35 am - 11:45 am
Discussion
11:45 am - 11:55 am
"Desmosomal Cadherin Association with Tctex-1 and Contraction-Arp2/3 Drives Perijunctional Actin Polymerization to Promote Epidermal Stratification"
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Novel Functions for Desmosomes in the Epidermis"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Cellular Stress Responses in Homeostasis and Degeneration
6:00 pm - 6:20 pm
"Age-Selective Segregation of Organelles During Stem Cell Division"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
"Regulation of the Hair Follicle Stem Cell Niche During Hair Growth, Pigmentation and Aging"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 7:05 pm
"Translating Epitranscriptome in Skin Stem Cells"
7:05 pm - 7:15 pm
Discussion
7:15 pm - 7:25 pm
"Bimodal Evolution of Clone Size Variation in the Interfollicular Epidermis Persists upon UVB Irradiation: Implications for Carcinogenesis"
7:25 pm - 7:30 pm
Discussion
7:30 pm - 7:50 pm
"Epithelial Cell Death Pathways in Inflammatory Diseases"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pm
Epithelia Micro-Environment in Homeostasis and Disease
9:00 am - 9:20 am
"Spatial Transcriptomics and Single-Cell Lineage Tracing"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Fibroblast Heterogeneity in Skin Homeostasis and Disease"
9:50 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:40 am
"Memory of Inflammation in Epidermal Stem Cells"
10:40 am - 10:45 am
Discussion
10:45 am - 11:05 am
"Principles of Skin Tissue Regeneration by Live Imaging"
11:05 am - 11:15 am
Discussion
11:15 am - 11:25 am
"Hair Follicle Epidermal Stem Cells Define a Niche for Tactile Sensation"
11:25 am - 11:30 am
Discussion
11:30 am - 11:50 am
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:20 pm
"Hair Follicle Stem Cells in Androgenetic Alopecia"
12:20 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Novel Translational Concepts in Epithelial Based Disease
6:00 pm - 6:20 pm
"Translating Human Skin Microbiome Research for Primary Immune Deficiency and Atopic Dermatitis Patients"
6:20 pm - 6:30 pm
Discussion
6:30 pm - 6:40 pm
"Novel Approaches to Target p63-Associated Genodermatoses"
6:40 pm - 6:45 pm
Discussion
6:45 pm - 6:55 pm
"Epigenetic Enhancers and SCC"
6:55 pm - 7:00 pm
Discussion
7:00 pm - 7:20 pm
"Causative Gene Identification and Pathogenesis-Based Therapies in Genodermatoses"
7:20 pm - 7:30 pm
Discussion
7:30 pm - 7:40 pm
"Neutrophils Play a Key Role in Acute and Chronic Itch"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Epigenetic Control of CD36+ Metastasis Initiating Cells by Dietary Fatty Acids"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure