| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | KEYNOTE LECTURES |
| Discussion Leader: Richard L. Huganir (HHMI/Johns Hopkins) |
| 7:30 pm - 8:30 pm | Roger Nicoll (UCSF)
"Where are memories stored: A view from the postsynaptic membrane" |
| 8:30 pm - 9:30 pm | Gary Westbrook (Vollum Institute)
"New neurons and new synapses in the dentate gyrus" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:45 am | Group Photo |
| 9:00 am - 10:45 am | PRESYNAPTIC FUNCTION AT EAA SYNAPSES |
| Discussion Leader: Morgan Sheng (HHMI/Massachusetts Institute of Technology) |
| 9:00 am - 9:35 am | Tom Sudhof (University of Texas Southwestern Medical Center)
"How calcium triggers neurotransmitter release" |
| 9:35 am - 10:10 am | Christian Rosenmund (Max Planck Institute)
"Molecular mechanisms contributing to the heterogeneity of presynaptic function" |
| 10:10 am - 10:45 am | Dick Tsien (Stanford)
"Single vesicles, kiss-and-run, and single glutamatergic synapses" |
| 10:45 am - 11:15 am | Coffee Break |
| 11:15 am - 12:30 pm | STRUCTURE AND FUNCTION OF EAA RECEPTORS |
| Discussion Leader: Paul Worley (Johns Hopkins) |
| 11:15 am - 11:50 am | Eric Gouaux (Columbia)
"Structure and function of ionotropic glutamate receptors" |
| 11:50 am - 12:25 pm | Yael Stern-Bach (Hebrew University of Jerusalem)
"Mechanism of AMPA receptor allosteric inhibition" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:30 pm | Free Time |
| 4:30 pm - 6:00 pm | Posters |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | SYNAPTIC SCAFFOLDING PROTEINS |
| Discussion Leader: Suzanne Zukin (Albert Einstein College of
Medicine) |
| 7:30 pm - 8:05 pm | Morgan Sheng (MIT)
"Molecular modification of excitatory synapses by activity" |
| 8:05 pm - 8:40 pm | Ed Ziff (NYU Medical Center)
"Role of AMPA receptor assembly and trafficking in synaptic regulation" |
| 8:40 pm - 9:15 pm | David Bredt (UCSF)
"Synaptic glutamate receptors regulated between the sheets" |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 10:45 am | PROTEIN TRAFFICKING AT EXCITATORY SYNAPSES |
| Discussion Leader: Peter Seeburg (University of Heidelberg) |
| 9:00 am - 9:35 am | Craig Garner (Stanford University)
"Nascent assembly of glutamatergic synapses" |
| 9:35 am - 10:10 am | Bob Wenthold (NIH)
"Trafficking of NMDA Receptors to the Synapse" |
| 10:10 am - 10:45 am | Daniel Choquet (Universite de Bordeaux)
"Single molecule imaging of AMPARs movements in synapses"
|
| 10:45 am - 11:15 am | Break |
| 11:15 am - 12:30 pm | REGULATION OF EAA RECEPTOR FUNCTION (cont'd) |
| Discussion Leader: Rob Malenka (Stanford University) |
| 11:15 am - 11:50 am | John Isaac (University of Bristol)
"Regulation of AMPA receptor subunit composition at hippocampal synapses" |
| 11:50 am - 12:25 pm | Juan Lerma (Instituto Cajal)
"Non-canonical signaling by ionotropic kainate receptors" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:30 pm | Free Time |
| 4:30 pm - 6:00 pm | Posters |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | REGULATION OF NMDA RECEPTOR FUNCTION |
| Discussion Leader: Gary Westbrook (Vollum Institute) |
| 7:30 pm - 8:05 pm | Suzanne Zukin (Albert Einstein College of Medicine)
"Regulation of NMDA receptor trafficking and gating by protein kinases" |
| 8:05 pm - 8:40 pm | Mike Salter (University of Toronto)
"Ins and outs of regulating NMDA receptors" |
| 8:40 pm - 9:15 pm | Katherine Roche (NIH)
"Regulation of glutamate receptor trafficking" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 10:45 am | EAAs AND NEURONAL DEVELOPMENT |
| Discussion Leader: Gina Turrigiano (Brandeis University) |
| 9:00 am - 9:35 am | Karel Svoboda (Cold Spring Harbor Labs)
"Experience-dependent synaptic plasticity" |
| 9:35 am - 10:10 am | Holly Cline (Cold Spring Harbor Labs)
"Experience dependent plasticity of glutamatergic synapses in vivo" |
| 10:10 am - 10:45 am | Mark Bear (Brown)
"Regulation of glutamate receptor function by experience in visual cortex" |
| 10:45 am - 11:15 am | Break |
| 11:15 am - 12:30 pm | GENETIC APPROACHES TO EAA RECEPTOR FUNCTION IN INVERTEBRATES |
| Discussion Leader: Steve Heinemann (Salk Institute) |
| 11:15 am - 11:50 am | Josh Kaplan (Harvard)
"Mechanisms regulating glutamate receptor abundance at C. elegans synapses" |
| 11:50 am - 12:25 pm | Villu Maricq (University of Utah)
"Genetic Dissection of Glutamatergic Signaling: New Mechanisms and Molecules" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:30 pm | Free Time |
| 4:30 pm - 6:00 pm | Posters |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| 7:30 pm - 9:30 pm | GENETIC APPROACHES TO EAA RECEPTOR FUNCTION IN VERTEBRATES |
| Discussion Leader: Dick Tsien (Stanford University) |
| 7:30 pm - 8:05 pm | Peter Seeburg (University of Heidelberg)
"Probing the role of LTP for spatial memories" |
| 8:05 pm - 8:40 pm | Steve Heinemann (Salk Institute)
"Trans-Synaptic Eph-Ephrin Signaling is Essential for Synaptic Plasticity
(LTP) in the Hippocampus. Is More LTP a Good Thing?" |
| 8:40 pm - 9:15 pm | Susumu Tonegawa (MIT)
"Roles of hippocampal NMDA receptors in learning and memory" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | SYNAPTIC PLASTICITY AT EAA SYNAPSES |
| Discussion Leader: Hollis Cline (Cold Spring Harbor Laboratories) |
| 9:00 am - 9:35 am | Rob Malenka (Stanford)
"Synaptic plasticity in the mesolimbic dopamine system" |
| 9:35 am - 10:10 am | Rob Malinow (Cold Spring Harbor Labs)
"Receptor trafficking and synaptic plasticity" |
| 10:10 am - 10:45 am | Paul Worley (Johns Hopkins)
"Immediate early genes that function at the excitatory synapse" |
| 10:45 am - 11:15 am | Break |
| 11:15 am - 11:50 am | Gina Turrigiano (Brandeis University)
"Synaptic plasticity in developing cortical networks" |
| 11:50 am - 12:25 pm | Mike Ehlers (Duke)
"Proteomics, the proteasome, and postsynaptic plasticity" |
| 12:30 pm | Lunch |
| 1:30 pm - 2:30 pm | Free Time |
| 2:30 pm - 4:30 pm | SHORT TALKS |
| Discussion Leader: Richard L. Huganir (HHMI/Johns Hopkins) |
| 2:30 pm - 2:50 pm | Dwight Bergles (Johns Hopkins)
"Interactions between transporters and receptors at excitatory synapses" |
| 2:50 pm - 3:10 pm | Jane Sullivan (University of Washington)
"Is Synaptotagmin I a calcium sensor that controls neurotransmitter release?" |
| 3:10 pm - 3:30 pm | Kim McAllister (UC Davis)
"Rapid recruitment of NMDA receptors to nascent cortical synapses" |
| 3:30 pm - 3:50 pm | Pavel Osten (Max Planck Institute)
"AMPA receptor synaptic function and structural plasticity" |
| 3:50 pm - 4:10 pm | Hannah Monyer (University of Heidelberg)
Genetic manipulations of AMPA receptors in GABAergic interneurons |
| 4:10 pm - 4:30 pm | TBA |
| 4:30 pm - 6:00 pm | Posters |
| 6:00 pm | Dinner |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |
