Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: The Synaptome Architecture of the Mouse and Human Brain
3:45 pm - 3:50 pm
Introduction by Discussion Leader
3:50 pm - 4:20 pm
"The Synaptome Architecture of the Human Brain"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Molecular Diversity of Excitatory Synapses: Nanoscale Architecture and its Functional Implications
7:30 pm - 7:40 pm
"Clustering of Latrophilin-3 Regulates Excitatory Synapse Formation"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Calcium-Dependent Proximity Labelling in Synapses Reveals Novel Activity-Dependent Signaling Complex"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Evaluating a Cell Type-Specific Mechanism of Glutamatergic Synapse Stability and Organization"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 8:25 pm
"Human Synapses in Focus: An iPSC-Based Approach to Synaptic Organization and Function in Health and Disease"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Dual Functions of RIN1 in AMPA Receptor Trafficking and Structural Plasticity at Excitatory Synapses"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"Regulation of Spatial Segregation of AMPA Receptors During Environmental Enrichment"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
"Neuronal Cholesterol Turnover Influences Synaptic Maturation and Function"
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
"GluA4: An Unusual AMPAR for Unusual Excitatory Synapses"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Synaptic Plasticity and Information Processing: Mechanisms Underlying Complex Behaviors
9:00 am - 9:10 am
"Organization of Top-Down Signals from Cingulate Areas to the Primary Visual Cortex"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
"The Impact of a Human-Specific Genetic Modifier SRGAP2C on Cortical Circuit Function and Behavior"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Excitatory Glycine Receptors (eGlyRs) in the Ventral Hippocampus Control Synaptic Plasticity and Anxiety-Related Behaviors"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Decoding Experience-Driven Cortical Activity and Gene Expression Alterations in a Mouse Model of Autism"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Striatal Glutamate Delta-1 Receptor (GluD1) Regulates Protein Kinase C (PKC) -Dependent NMDAR Plasticity Necessary for Cognitive Flexibility"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"An ASD Risk Gene Involved in Regulating Deep Layer Cortical Connectivity"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
"NMDA Receptor-BK Channel Functional Coupling is Altered in the Fragile-X Syndrome Mouse Model"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
"A Trans-Synaptic Autophagy Mechanism Controls Pain"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: New Voices, Lasting Impact: Junior Principal Investigators Shaping the Excitatory Synapses and Brain Function Field
1:30 pm - 2:30 pm
Panel Discussion
The Role of Junior Principal Investigators as the Next Generation Mentors of the Excitatory Synapses Field
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes