| SUNDAY | 
| 4:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:45 pm) | 
| 6:00 pm | Dinner | 
| 7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff | 
| 7:40 pm - 9:30 pm | FGF SIGNALING: AN OVERVIEW | 
|  | Discussion Leader: Claudio Basilico (New York University, USA) | 
| 7:40 pm - 8:20 pm | Moosa Mohammadi (New York University, USA) "Structural basis for FGF receptor activation in human diseases"
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| 8:20 pm - 8:35 pm | Discussion | 
| 8:35 pm - 9:15 pm | David Ornitz (Washington University, USA) "FGF-WNT gene regulatory network regulates lung mesenchyme development"
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| 9:15 pm - 9:30 pm | Discussion | 
| 9:30 pm | Poster Session | 
| MONDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | FGF FUNCTION IN ORGANOGENESIS | 
|  | Discussion Leader: Gail Martin (University of California, San Francisco, USA) | 
| 9:00 am - 9:20 am | Matthew Hoffman (NIH, Bethesda, USA) "Heparan sulfate regulation of FGF10-mediated submandibular gland branching morphogenesis"
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| 9:20 am - 9:30 am | Discussion | 
| 9:30 am - 9:50 am | Tom Kornberg (University of California, San Francisco, USA) "The roles of Drosophila FGF in organ induction and mitogenesis"
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| 9:50 am - 10:00 am | Discussion | 
| 10:00 am | Coffee Break / Group Photo | 
| 10:30 am - 10:50 am | Angelike Stathopoulos (CalTech, USA) "The coordination of cell movements during Drosophila gastrulation: the role of FGF signaling"
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| 10:50 am - 11:00 am | Discussion | 
| 11:00 am - 11:20 am | Suzi Mansour (University of Utah, USA) "FGF signaling in inner ear development"
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| 11:20 am - 11:30 am | Discussion | 
| 11:30 am - 11:50 am | Nobuyuki Itoh (University of Kyoto) "The role of FGF16 in heart development"
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| 11.50 am -12:00 pm | Discussion | 
| 12:00 pm - 12:10 pm | Mark Lewandoski (National Cancer Institute, USA) "The vertebrate limb is patterned by BMP-mediated modulation of FGF signals via Sprouty expression"
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| 12:10 pm - 12:15 pm | Discussion | 
| 12:15 pm - 12:25 pm | Beat Trueb (University of Bern, Switzerland) "Mice with a targeted disruption of the Fgfrl1 gene die at birth due to alterations in the diaphragm"
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| 12:25 pm - 12:30 pm | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 5:30 pm | Poster Session | 
| 5:30 pm - 7:30 pm | DEVELOPMENT OF THE NERVOUS SYSTEM | 
|  | Discussion Leader: Ivor Mason | 
| 5:30 pm - 5:50 pm | Ann Calof (University of California, Irvine, USA) "FGFs, neurogenesis in the primary olfactory system, and the origin of GnRH-expressing neurons in the mouse"
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| 5:50 pm - 6:00 pm | Discussion | 
| 6:00 pm - 6:20 pm | Albert Basson (King's College London, UK) "FGF signalling in cerebellar morphogenesis"
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| 6:20 pm - 6:30 pm | Discussion | 
| 6:30 pm - 6:50 pm | Hisashi Umemori (University of Michigan, USA) "Specific Synapse Formation by FGFs"
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| 6:50 pm - 7:00 pm | Discussion | 
| 7:00 pm - 7:20 pm | Jean Hebert (Albert Einstein College of Medicine, USA) "FGF signaling acts as an organizer for the telencephalon"
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| 7:20 pm - 7:30 pm | Discussion | 
| 8:00 pm | Dinner | 
| 9:15 pm | Poster Session | 
| TUESDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | SKELETAL BIOLOGY | 
|  | Discussion Leader: David Ornitz (Washington University, USA) | 
| 9:00 am - 9:20 am | William Horton (University of Oregon Heath Science campus and Shriners Hospital for Children, USA) "Strategies to counter excessive FGFR3 signals"
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| 9:20 am - 9:30 am | Discussion | 
| 9:30 am - 9:50 am | Victor Nurcombe (Institute of Molecular and Cell Biology, Singapore) "Regulation of FGF/BMP loops by heparans during osteogenesis"
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| 9:50 am - 10:00 am | Discussion | 
| 10:00 am | Coffee Break | 
| 10:30 am - 10:50 am | Irene Hung (University of Utah, USA) "FGF Signaling in Skeletal Development"
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| 10:50 am - 11:00 am | Discussion | 
| 11:00 am - 11:20 am | Janet Henderson (McGill University, Canada) "FGF18 to promote bone regeneration and repair"
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| 11:20 am - 11:30 am | Discussion | 
| 11.30 am - 11:50 am | Claudio Basilico (New York University, USA) "Key events determine the growth-inhibitory response of chondrocytes to FGF signaling"
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| 11:50 am - 12:00 pm | Discussion | 
| 12:00 pm - 12:10 pm | Christoph Ladel (Merck Serono Research, Italy) "FGF18 as therapeutic for osteoarthritis: Efficacy of rhFGF18 in preclinical models of osteoarthritis"
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| 12:10 pm - 12:15 pm | Discussion | 
| 12:15 pm - 12:25 pm | Tonia Vincent (Kenedy Institute, London) "FGF2 is an intrinsic chondroprotective agent, which suppresses the proteinase ADAMTS5, and delays cartilage degradation in osteoarthritis"
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| 12:25 pm - 12:30 pm | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 5:30 pm | Poster Session | 
| 5:30 pm - 7:30 pm | NERVOUS SYSTEM FUNCTION AND REPAIR | 
|  | Discussion Leader: Klaus Unsicker (University of Heidelberg, Germany) | 
| 5:30 pm - 5:50 pm | Oliver von Bohlen und Halbach (University of Heidelberg, Germany) "FGF-2 in an animal model of depression"
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| 5:50 pm - 6:00 pm | Discussion | 
| 6:00 pm - 6:20 pm | Marco Riva (University of Milan, Italy) "FGF2 regulation in drug abuse and stress response"
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| 6:20 pm - 6:30 pm | Discussion | 
| 6:30 pm - 6:50 pm | Claudia Grothe (University of Hannover, Germany) "Regenerative potential of endogenous and cell-based applied FGF-2 in two animal models, Parkinson's disease and peripheral nerve regeneration"
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| 6:50 pm - 7:00 pm | Discussion | 
| 7:00 pm - 7:20 pm | Mitchell Goldfarb (City University, New York, USA) "FHF control of sodium channel physiology and neuronal function: insights from mutant mice"
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| 7:20 pm - 7:30 pm | Discussion | 
| 8:00 pm | Dinner | 
| 9:15 pm | Poster Session | 
| WEDNESDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | TUMORIGENESIS | 
|  | Discussion Leader: Victor Nurcombe (Institute of Molecular and Cell Biology, Singapore) | 
| 9:00 am - 9:20 am | François Radvanyi (Institut Curie, France) "Role of FGFR3 in tumours"
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| 9:20 am - 9:30 am | Discussion | 
| 9:30 am - 9:50 am | Richard Grose (Institute of Cancer, UK) "Epithelial FGFR2: oncogene or tumour suppressor?"
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| 9:50 am - 10:00 am | Discussion | 
| 10:00 am | Coffee Break | 
| 10:30 am - 10:50 am | Michael Seckl (Imperial College, UK) "FGF-2 triggers a novel signaling machine enhancing translation of anti-apoptotic proteins and driving chemoresistance in lung cancer"
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| 10:50 am - 11:00 am | Discussion | 
| 11:00 am - 11:20 am | Dina Ron (Technion, Israel) "Sef regulation in normal and cancer cells"
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| 11:20 am - 11:30 am | Discussion | 
| 11:30 am - 11:50 am | Marco Presta (University of Brescia, Italy) "FGF2 as a damage-associated molecular pattern (DAMP) proangiogenic cytokine"
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| 11.50 am - 12:00 pm | Discussion | 
| 12:00 pm - 12:10 pm | Igor Prudovsky (Maine Medical Centre, USA) "Repression of CBF1-mediated Notch signaling results in FGF1 export and cell transformation"
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| 12:10 pm - 12:15 pm | Discussion | 
| 12:15 pm - 12:25 pm | Soo Hyun Kim (University College, UK) "Anosmin-1 mediates crosstalk between TGF-beta 1 and FGFR1 signal pathways in development and tumourigenesis"
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| 12:25 pm - 12:30 pm | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 5:30 pm | Poster Session | 
| 5:30 pm - 7:30 pm | HOMEOSTASIS | 
|  | Discussion Leader: Sabine Werner | 
| 5:30 pm - 5:50 pm | Toru Imamura (National Institute of Advanced Industrial Science and Technology) "BetaKlotho is required for FGF21 signaling"
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| 5:50 pm - 6:00 pm | Discussion | 
| 6:00 pm - 6:20 pm | Itaru Urakawa (Kirin Brewery Co, Japan) "Role of FGF23 in phosphate homeostasis"
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| 6:20 pm - 6:30 pm | Discussion | 
| 6:30 pm - 6:50 pm | Makoto Kuro-o (University of Texas, USA) "Interaction between the Klotho and FGF19 family members"
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| 6:50 pm - 7:00 pm | Discussion | 
| 7:00 pm - 7:20 pm | Alexei Kharitonenkov (Lilly Research Laboratories, USA) "Metabolic actions of FGF21"
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| 7:20 pm - 7:30 pm | Discussion | 
| 7:30 pm - 8:00 pm | Business Meeting | 
|  | (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) | 
| 8:00 pm | Dinner | 
| 9:15 pm | Poster Session | 
| THURSDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am - 12:30 pm | STEM CELLS, REGENERATION AND TISSUE REPAIR | 
|  | Discussion Leader: Janet Henderson (McGill University, Canada) | 
| 9:00 am - 9:20 am | Sabine Werner (Eidgenössische Technische Hochschule Zurich, Switzerland) "Fibroblast growth factors in epithelial morphogenesis and tissue repair"
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| 9:20 am - 9:30 am | Discussion | 
| 9:30 am - 9:50 am | Gerald de Haan (University Medical Center Groningen, Netherlands) "Culturing hematopoietic stem cells with FGFs"
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| 9:50 am - 10:00 am | Discussion | 
| 10:00 am | Coffee Break | 
| 10:30 am - 10:50 am | Bradley Olwin (University of Colorado, USA) "A critical role for FGFR4 in regeneration of skeletal muscle"
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| 10:50 am - 11:00 am | Discussion | 
| 11:00 am - 11:20 am | Robert Friesel (Maine Medical Centre, USA) "Overexpression of Spry1 in Chondrocytes Results in Attenuated FGFR Ubiquitinylation and Sustains ERK activation Results in Chondrodysplasia"
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| 11:20 am - 11:30 am | Discussion | 
| 11:30 am - 11:45 am | John Whitelock (University of New South Wales, Australia) "HS on perlecan determines the fate of chondorcytes via its interactions with FGFs"
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| 11.45 am - 11:53 am | Discussion | 
| 11:53 am - 12:03 pm | Shinya Murakami (Osaka University, Japan) "Trial in Periodontal Tissue Regeneration Using Fibroblast Growth Factor-2:Randomized Controlled Phase II Clinical Trial8Randomized Controlled Phase II Clinical Trial"
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| 12:03 pm - 12:08 pm | Discussion | 
| 12:08 pm - 12:22 pm | Saverio Bellusci (Children's Hospital Los Angeles, USA) "Induction of FGF10 in the ileal crypt epithelium after massive small bowel suggests a role for FGF10 in gut adaptation"
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| 12:22 pm - 12:30 pm | Discussion | 
| 12:30 pm | Lunch | 
| 1:30 pm - 4:00 pm | Free Time | 
| 4:00 pm - 5:30 pm | Poster Session | 
| 5:30 pm - 7:30 pm | REGULATING THE FGF SIGNAL | 
|  | Discussion Leader: Moosa Mohammedi (New York University, USA) | 
| 5:30 pm - 5:50 pm | Jeremy Turnbull (University of Liverpool, UK) "Decoding the chemical biology of heparan sulfate: an ES-MS sequencing strategy reveals specific modulation of FGF signalling"
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| 5:50 pm - 6:00 pm | Discussion | 
| 6:00 pm - 6:10 pm | Helen Makarenkova (The Neurosciences Institute, USA) "A molecular basis for FGF gradient formation and regulation of branching morphogenesis"
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| 6:10 pm - 6:15 pm | Discussion | 
| 6:15 pm - 6:25 pm | Ugo Cavallaro (IFOM-IEO, Italy) "The NCAM/FGFR cross talk: a novel paradigm in FGFR signalling"
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| 6:25 pm - 6:30 pm | Discussion | 
| 6:30 pm - 6:50 pm | Fen Wang (Texas A&M, USA) "FGF signaling in prostate development and tumorigenesis"
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| 6:50 pm - 7:00 pm | Discussion | 
| 7:00 pm - 7:20 pm | Antoni Wiedlocha (Institute for Cancer Research, Oslo, Norway) "Role of p38 MAPK in translocation of FGF-1 into cells"
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| 7:20 pm - 7:30 pm | Discussion | 
| 8:00 pm | Dinner | 
| 9:15 pm | Poster Session | 
| FRIDAY | 
| 7:30 am - 8:30 am | Breakfast | 
| 9:00 am | Depart |