Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Mechanisms of Mucosal Tolerance and Food Allergy
3:45 pm - 3:50 pm
Introduction by Discussion Leader
3:50 pm - 4:25 pm
"Lessons & Questions After 45 Years in Food Allergy Research"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Innate and Adaptive Immune Responses in Food Allergy
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:45 pm
"BCR Density Limits Survival of IgE Germinal Center B Cells"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:00 pm
"Dietary Fatty Acids Regulate Local IgE Responses by Modulating Regulatory T Cells in the Gut"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"Paneth Cell Dysfunction and Lysozyme Deficiency is Associated with Peanut Allergy"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:40 pm
"Eosinophil-Intestinal Epithelial Cell Interactions Regulate Food Allergy Outcomes"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
"Toxins Induced Non-IgE-Mediated Intestinal Allergic Response During Clostridioides Difficile Infection"
9:00 pm - 9:10 pm
Discussion
9:10 pm - 9:20 pm
"Tick Bites Expand Intermediate Monocytes and Dermal Dendritic Cells Linked to Type 2-Skewing in Alpha-Gal Syndrome"
9:20 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Origins and Interventions in Food Allergy: Microbiome, Environment, Genetics, and Immune-Based Therapies
9:00 am - 9:10 am
"Dissecting the Origins of Dietary Epitope Immunodominance to Guide Tolerogenic Engineering"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
"Characterizing Antibody Targets in Oral Tolerance"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
"Epitope-Specific Neutralizing IgG4 Antibodies Define Natural and Acquired Tolerance in Peanut Allergy"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
"Quantifying Peanut-Allergen Content in Peanut-Containing Foods: Does Content and Consistency Matter?"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
"Metabolomic Profiles Associated with SLIT and OIT"
10:10 am - 10:20 am
Discussion
10:20 am - 10:30 am
"Per & Polyfluoroalkyl Substances (PFAS) Levels and Atopy Throughout Early Life"
10:30 am - 10:40 am
Discussion
10:40 am - 10:50 am
"Protein Language Model Guided Discovery of Microbial Protease Allergens"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Scientific Futures: Navigating Career Pathways
1:30 pm - 1:35 pm
Introduction by Discussion Leader
1:35 pm - 2:20 pm
Panel Discussion
Careers for Curious Minds
2:20 pm - 2:30 pm
General Discussion
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes