| SUNDAY |
| 4:00 pm - 8:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
| 7:40 pm - 9:30 pm | Glia and Brain Development |
| Discussion Leader: Harry Sontheimer (University of Alabama at Birmingham) |
| 7:40 pm - 8:05 pm | Beth Stevens (Children's Hospital/Harvard University)
"Pruning CNS Synapses: An Active Role for Glia and Immune Molecules"
|
| 8:05 pm - 8:15 pm | Discussion |
| 8:15 pm - 8:40 pm | Cagla Eroglu (Duke University)
"Astrocytes Orchestrate Dendritic Spine Formation and Maturation"
|
| 8:40 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:20 pm | Nicola Allen (Salk Institute)
"The role of astrocytes in synapse formation and maturation genesis"
|
| 9:20 pm - 9:30 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Group Photo |
| 9:00 am - 12:30 pm | Astrocytes and Synaptic Communication |
| Discussion Leader: Vlad Parpura (University of Alabama at Birmingham) |
| 9:00 am - 9:25 am | Richard Robitalle (University of Montreal)
"Astrocytes detect and modulate basal synaptic transmission"
|
| 9:25 am - 9:30 am | Discussion |
| 9:30 am - 9:55 am | Andrea Volterra (University of Lausanne)
"Anatomical-functional organization of astrocyte-synapse communications in the adult hippocampus"
|
| 9:55 am - 10:00 am | Discussion |
| 10:00 am | Coffee Break |
| 10:30 am - 10:55 am | Dimitri Rusakov (University College London)
"Basic principles of Ca2+ signal integration by astrocytes"
|
| 10:55 am - 11:00 am | Discussion |
| 11:00 am - 11:30 am | Stéphane Oliet (Inserm U862 - Neurocentre Magendie)
"Surface dynamics of astroglial glutamate transporter GLT-1"
|
| 11:30 am - 11:40 am | Discussion |
| 12:00 pm - 12:10 pm | Trainee Presentation: Catherine Christian (Stanford University)
"Thalamic astrocytes potentiate GABA transmission"
|
| 12:10 pm - 12:15 pm | Discussion |
| 12:15 pm - 12:25 pm | Trainee Presentation: Dustin Hines (Tufts Med Sch)
"Inhibition of the SNARE sensitive pathway in astrocytes attenuates damage following stroke"
|
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Neuronal Metabolism and Glia |
| Discussion Leader: Gerald Dienel (University of Arkansas for Medical Sciences) |
| 7:30 pm - 8:00 pm | Pierre Magistretti (King Abdullah University of Science and Technology (KAUST))
"Astrocyte-neuron metabolic cooperation"
|
| 8:00 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:40 pm | Bruce Ransom (University of Washington)
"Metabolic support of white matter and myelinated axon function by glia"
|
| 8:40 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:20 pm | Jeffery Rothstein (Johns Hopkins University)
"Oligodendroglia as central supporters of neurons/axons and participation in neurodegeneration"
|
| 9:20 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Model Approaches to Study Glia |
| Discussion Leader: Ken McCarthy (University of North Carolina) |
| 9:00 am - 9:30 am | Marc Freeman (UMass Med School)
"Cell-cell communication during astrocyte morphogenesis in Drosophila"
|
| 9:30 am - 9:35 am | Discussion |
| 9:35 am - 10:05 am | Bruno Weber (University of Zurich)
"Two Photon Imaging of Energy Substrates in Neurons and Astrocyte"
|
| 10:05 am - 10:10 am | Discussion |
| 10:10 am | Coffee Break |
| 10:40 am - 11:10 am | Dwight Bergles (Johns Hopkins Med Sch)
"In vivo imaging studies of astrocyte Ca2+ signaling"
|
| 11:10 am - 11:15 am | Discussion |
| 11:15 am - 11:45 am | Bal Khakh (UCLA)
"Uncovering the rules for astrocyte engagement in neuronal circuits using optical and genetic approaches" |
| 11:45 am - 11:50 am | Discussion |
| 12:00 pm - 12:10 pm | Trainee Presentation: Anna Molofsky (Langley Porter Psychiatric Institute/UCSF)
"An astrocyte encoded scaffold in the ventral spinal cord directs axon guidance and motor neuron subtype by secretion of Sema3a"
|
| 12:10 pm - 12:15 pm | Discussion |
| 12:15 pm - 12:25 pm | Trainee Presentation: Lasse Dissing-Olesen (University of British Columbia)
"Activation of neuronal NMDA receptors triggers rapid microglial process outgrowth; evidence for neuron-microglia communication"
|
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Endocannabinoids and Glia |
| Discussion Leader: Jaideep Bains (University of Calgary) |
| 7:30 pm - 8:00 pm | Xia Zhang (University of Ottawa)
"Glia and Memory"
|
| 8:00 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:40 pm | Giovanni Marsicano (University of Bordeaux)
"The roles of astroglial CB1 receptors"
|
| 8:40 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:20 pm | Thomas Nevian (University of Bern)
"Astrocyte calcium signaling in synaptic plasticity"
|
| 9:20 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Glia and Behavioral Control |
| Discussion Leader: Bruce Ransom (University of Washington) |
| 9:00 am - 9:40 am | Phil Haydon (Tufts Med Sch)
"Astrocytic regulation of purines in vivo and their impact on sleep homeostasis"
|
| 9:40 am - 9:55 am | Discussion |
| 9:55 am | Coffee Break |
| 10:10 am - 10:50 am | Maiken Nedergaard (University of Rochester)
"The Nightlife of Astrocytes"
|
| 10:50 am - 11:05 am | Discussion |
| 11:05 am - 11:45 am | Christian Giaume (College de France)
"The role of astroglial connexins in the regulation of sleep-wake cycle" |
| 11:45 am - 12:00 pm | Discussion |
| 12:00 pm - 12:10 pm | Trainee Presentation: Sophia Bardehle (Ludwig-Maximilians-Universität München)
"In vivo live imaging of reactive astrocytes after traumatic brain injury reveals heterogeneity with juxtavascular proliferation"
|
| 12:10 pm - 12:15 pm | Discussion |
| 12:15 pm - 12:25 pm | Trainee Presentation: Maria Sild (McGill University)
"Radial glial process motility regulates excitatory synapse properties"
|
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair |
| 7:30 pm - 9:30 pm | Brain Disorders and Glia |
| Discussion Leader: Richard Ransohoff (Cleveland Clinic Foundation) |
| 7:30 pm - 8:00 pm | David Attwell (University College London)
"Ischaemia-evoked damage to oligodendrocytes: the roles of glutamate receptors and K+" |
| 8:00 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:40 pm | Justin Lee (Korea Institute of Science & Technology)
"Mechanisms of glutamate release from astrocytes"
|
| 8:40 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:20 pm | Michael Sofroniew (UCLA)
"Reactive astrogliosis and the impact on brain function"
|
| 9:20 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Microglia and Synaptic Stripping |
| Discussion Leader: Monica Carson (University of California Riverside) |
| 9:00 am - 9:30 am | Richard Ransohoff (Cleveland Clinic Foundation)
"Macrophages of the CNS: Provenance matters!" |
| 9:30 am - 9:35 am | Discussion |
| 9:35 am - 10:05 am | Cornelius Gross (EMBL)
"A role for microglia in neural circuit maturation"
|
| 10:05 am - 10:10 am | Discussion |
| 10:10 am | Coffee Break |
| 10:40 am - 11:10 am | Shumin Duan (Zhejiang University School of Medicine)
"A novel pathway for purine-mediated macropinocytosis in microglia"
|
| 11:10 am - 11:15 am | Discussion |
| 11:15 am - 11:45 am | Jonathan Kipnis (University of Virginia)
"Microglia - scavengers of Rett pathology"
|
| 11:45 am - 11:50 am | Discussion |
| 12:00 pm - 12:10 pm | Trainee Presentation: Long-Jun Wu (Rutgers, The State University of New Jersey)
"Microglia proton channel: pH regulation and beyond"
|
| 12:10 pm - 12:15 pm | Discussion |
| 12:15 pm - 12:25 pm | Trainee Presentation: Stefanie Robel (University of Alabama at Birmingham)
"The role of reactive astrocytes in epilepsy"
|
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Glial Control of Blood Flow |
| Discussion Leader: Tailoi Chan-Ling (University of Sydney) |
| 7:30 pm - 8:00 pm | Eric Newman (University of Minnesota)
"Glial regulation of the retinal vasculature in vivo"
|
| 8:00 pm - 8:10 pm | Discussion |
| 8:10 pm - 8:40 pm | Jessica Filosa (Georgia Health Sciences University)
"Role of TRPV4 channels in vasculo-glia--neuronal coupling"
|
| 8:40 pm - 8:50 pm | Discussion |
| 8:50 pm - 9:20 pm | Harry Sontheimer (University of Alabama Birgmingham)
"Disruption of astrocyte-vascular coupling during tumor invasion"
|
| 9:20 pm - 9:30 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |