| SUNDAY JULY 1 |
| AFTERNOON | ARRIVE AND REGISTER |
| 6:00p | Dinner |
| 7:30-7:35p | Welcome |
| I. Principles of mechano- and gravity sensing: Plants and Animals |
| Manning Correia / Mike Evans |
| 7:35-7:45 | Manning Correia (UTMB, Galveston) |
| 7:45-8:30 | David Corey (Harvard)
Principles of mechanotransduction in animal sense organs |
| 8:30- 8:40 | Mike Evans (Ohio State) |
| 8:40- 9:25 | Janet Braam (Rice)
Molecular and developmental responses of plants to mechanical forces |
| 9:25-9:35 | Discussion |
| 9:45- | POSTER SESSION |
| MONDAY 2 JULY |
| II. Mechanosensing in microorganisms/ organisms with cell walls |
| Ian Booth / Stan Roux |
| 9:00-9:05a | Ian Booth |
| 9:05-9:45a | Ching Kung (Madison)
MscL, a mechanosensitive channel of bacteria |
| 9:45-10:25a | Sergei Sukharev (Maryland)
The gating transition in the large bacterial mechanosensitive channel, MscL |
| 10:25-10:30a | Discussion |
| 10:30-11:00a | Coffee Break |
| 11:00-11:05a | Stan Roux |
| 11:05-11:45a | Roymarie Ballester (UCSB)
Cell wall sensor proteins of yeast |
| 11:45-12:25p | Colin Brownlee (MBL, Plymouth, UK)
Intracellular signaling mechanisms distinguishing mechanical and osmotic stresses in plants |
| 12:25-12:30p | Discussion |
| 12:30-1:30p | Lunch |
| 1:30- 6:00p | Informal discussions, activities |
| 6:00-7:30p | Dinner |
| III. Signal transduction cascades evoked by mechanical stress and gravity |
| Fred Sachs |
| 7:30-7:40p | Fred Sachs (SUNY Buffalo) |
| 7:40-8:15p | Mike Sheetz (Columbia)
Cell force transduction: Role of tyrosine phosphatases and kinases |
| 8:15-8:50p | Dan Cosgrove (Penn State)
Mechanisms of cell wall loosening in plants, or how a coleoptile gets bent |
| 8:50-9:20p | Eric Honoré (CNRS Valbonne)
Mechano-gated 2P domain K+ channels |
| 9:20-9:30p | Discussion |
| 9:30p - | POSTER SESSION |
| TUESDAY, JULY 3 |
| III. Signal transduction cascades evoked by mechanical stress and gravity, cont'd |
| Owen Hamill / John Kiss |
| 9:00-9:05a | Owen Hamill |
| 9:05-9:45a | John Frangos (UCSD)
The membrane-free volume theory of mechanochemical transduction |
| 9:45-10:25a | Elisabeth Burger (Free Univ.)
Mechanotransduction in bone: Role of the osteocyte network |
| 10:25-10:30a | Discussion |
| 10:30-11:00a | Coffee Break |
| 11:00-11:05 | John Kiss (Miami University, Ohio) |
| 11:05-11:45a | Wendy Boss (N. Carolina State)
Phosphoinositide signaling in gravitropism in plants |
| 11:45-12:25p | Heribert Hirt (Vienna)
MAP kinase pathways: Molecular plug-and-play chips of cellular bioinformatics |
| 12:25-12:30p | Discussion |
| 12:30-1:30p | Lunch |
| 1:30-6:00p | Informal discussions, activities |
| 6:00-7:30p | Dinner |
| IV. Mechanosensitive and other ion channels in mechano- and gravisensing |
| Jaime García-Añoveras / Nina Allen |
| 7:30-7:40p | Jaime García-Añoveras (Harvard) |
| 7:40-8:05p | Miriam Goodman (Columbia)
The molecular basis of touch in C. elegans |
| 8:05-8:30 | Ellen Lumpkin (UCSF)
Characterizing touch reception by Merkel cell-neurite complexes |
| 8:30-8:40 | Discussion |
| 8:40-8:50p | Nina Allen (North Carolina State
University) |
| 8:50-9:30p | Simon Gilroy (Penn State)
Ionic signaling during root gravitropism |
| 9:30- 9:40p | Discussion |
| 9:45p- | POSTER SESSION |
| WEDNESDAY, JULY 4 |
| IV. Mechanosensitive and other ion channels in mechano- and gravisensing, cont'd |
| Roger Hangartner / Corné Kros |
| 8:45-8:55a | Roger Hangartner (Indiana) |
| 8:55-9:20a | Gethyn Allen (UCSD)
Molecular mechanisms in the signaling network in guard cells of plants |
| 9:20-10:00a | Rainer Hedrich (Wurzberg)
Ion signaling mechanisms in coleoptile growth and gravitropism |
| 10:00-10:25a | Chris Wolverton (Ohio State)
Identification of a new gravity sensor in plants: A mechanosensor? |
| 10:25-10:30a | Discussion |
| 10:30-11:00a | Coffee Break |
| 11:00 - 11:10 | Corné Kros (Sussex) |
| 11:10-11:35a | Maggie Price (Iowa)
The role of DEG/ENaC ion channels in mechanosensation |
| 11:35-12:20 | Robert Fettiplace (Madison)
Forward and reverse transduction in auditory hair cells |
| 12:20-12:30p | Discussion |
| 12:30-1:30p | Lunch |
| 1:30- 6:00p | Informal discussions, activities |
| 6:00-7:30p | Dinner |
| IV. Mechanosensitive and other ion channels in mechano- and gravisensing, cont'd |
| Cathy Morris |
| 7:30-7:45p | Cathy Morris (Ottawa) |
| 7:45- 8:30p | Andrew French (Dalhousie)
Transduction and adaptation in arthropod mechanosensory neurons |
| 8:30-9:15p | Jim Hudspeth (Rockefeller)
Mechanical amplification by the transduction channels of hair cells |
| 9:15-9:30p | Discussion |
| 9:30p- | POSTER SESSION |
| THURSDAY, JULY 5 |
| V. Genetic approaches to mechanosensing and gravitropism |
| Maurice Kernan / Paul Blount |
| 8:45-8:55a | Maurice Kernan (SUNY Stonybrook) |
| 8:55-9:20a | Bassem Hassan (Baylor)
From flies to mice and back: Conservation of mechanoreceptor specification |
| 9:20-9:45a | Richard Walker (UCSD)
A mechanosensory transduction channel in Drosophila |
| 9:45-10:10a | Teresa Nicolson (MPI, Tübingen)
Mechanosensory mutants in Zebrafish |
| 10:10-10:20a | Discussion |
| 10:20-10:50a | Coffee Break |
| 10:50-11:00 | Paul Blount (UT Southwestern) |
| 11:00-11:40a | Patricia Wolff (MPI, Köln)
Auxin and its role in gravity perception in plants |
| 11:40-12:20p | Patrick Masson (Madison)
Genetic analysis of root gravitropism in Arabidopsis thaliana |
| 12:20-12:30p | Discussion |
| 12:30-1:30p | Lunch |
| 1:30-6:00p | Informal discussions, activities |
| 6:00-7:30p | Dinner |
| V. Genetic approaches to mechanosensing and gravitropism, cont'd |
| Martin Chalfie |
| 7:30-7:45p | Martin Chalfie (Columbia) |
| 7:45- 8:45p | Karen Steel (MRC, Nottingham)
Genetics of inner ear defects |
| 8:45- 9:00p | Discussion |
| 9:15-10:15p | BUSINESS MEETING |
| FRIDAY, JULY 6 |
| 7:30-8:30a | Breakfast |
| 9:00a | BUS DEPARTS |
