1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Initiating a Career in Blood Research
Gow Arepally (Duke University School of Medicine, United States)
3:45 pm - 4:15 pm
Marvin Nieman (Case Western Reserve University, United States) "Initiating a Career in Blood Research"
4:15 pm - 4:30 pm
4:30 pm - 6:00 pm
6:00 pm - 7:00 pm
7:30 pm - 9:30 pm
Building on the Basics: New Discoveries in Thrombosis and Hemostasis
Traci Mondoro (National Institutes of Health, United States) and Daniëlle Coenen (University of Kentucky, United States, United States)
7:30 pm - 7:45 pm
Irina Portier (University of Utah, United States) "The mTOR Pathway in Platelets Contributes to the Pathophysiology of Experimental Cerebral Malaria"
7:45 pm - 7:50 pm
7:50 pm - 8:05 pm
Dre'Von Dobson (University of North Carolina at Chapel Hill, United States) "Functional Characterization of Loci Associated with Circulating Fibrinogen Levels"
8:05 pm - 8:10 pm
8:10 pm - 8:25 pm
Viola Strijbis (Leiden University Medical Center, The Netherlands) "Modifications in the Thrombin Active Site S4 Subpocket Induce Resistance to Direct Thrombin Inhibitors"
8:25 pm - 8:30 pm
8:30 pm - 8:45 pm
Siobhan Branfield (Oakland University, United States) "Deciphering the TLT-1 Fibrinogen Ligand Interaction"
8:45 pm - 8:50 pm
8:50 pm - 9:05 pm
Vladimir Kolyadko (The Children's Hospital of Philadelphia, United States) "Allosteric Regulation of Coagulation Factor IXa Revealed by X-Ray Crystallography"
9:05 pm - 9:10 pm
9:10 pm - 9:25 pm
Helen Fogarty (Royal College of Surgeons in Ireland, Ireland) "Blood Transfusion Maintains Endothelial Cell Quiescence - Implications in Stroke Prevention in Paediatric Sickle Cell Anaemia"
9:25 pm - 9:30 pm
7:30 am - 8:30 am
9:00 am - 11:00 am
Platelets and Other Cells in Coagulation
Sidney Whiteheart (University of Kentucky, United States) and Ratnashree Biswas (Versiti Blood Research Institute, United States)
9:00 am - 9:15 am
Frederik Denorme (University of Utah, United States) "Procoagulant Platelet – Neutrophil Interactions Exacerbate Ischemic Stroke"
9:15 am - 9:20 am
9:20 am - 9:35 am
Nurul Aisha Zainal Abidin (Monash University, Australia) "An Extensional Strain Sensing Mechanosome Drives Adhesion-Independent Platelet Activation at Supraphysiological Hemodynamic Gradients"
9:35 am - 9:40 am
9:40 am - 9:55 am
Sarah Beck (University of Würzburg, Germany) "Spatio-Temporal Control of Fibrin Formation by Platelet Glycoprotein V"
9:55 am - 10:00 am
10:00 am - 10:15 am
Gagan Flora (University of Iowa, United States) "The Role of Pyruvate Dehydrogenase Kinases in Regulating Platelet Function and Thrombosis"
10:15 am - 10:20 am
10:20 am - 11:00 am
Pathways to Success: Navigating a Career in Science
Traci Mondoro (National Institutes of Health, United States)
Joshua Muia (Oklahoma State University Center for Health Sciences, United States)
Emily Waters (Novo Nordisk Inc, United States)
11:00 am - 12:30 pm
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
1:30 pm - 2:30 pm
Crosstalk with Coagulation
Marvin Nieman (Case Western Reserve University, United States) and Maria Barrachina (Harvard Medical School, Boston Children's Hospital, United States)
1:30 pm - 1:45 pm
Claudius Witzler (University Medical Center of the Johannes Gutenberg University Mainz, Germany) "Regulation of Metabolic Inflammation by Coagulation Signaling"
1:45 pm - 1:50 pm
1:50 pm - 2:05 pm
Chi Peng (University of Kentucky, United States) "Characterization of Platelets from A Newly Developed Obese Mouse Model: MS-NASH"
2:05 pm - 2:10 pm
2:10 pm - 2:25 pm
Aisling Rehill (Royal College of Surgeons in Ireland (RCSI), Ireland) "Metabolic Reprogramming is Essential for Myeloid Cell Hypercoagulability"
2:25 pm - 2:30 pm
2:30 pm - 3:00 pm
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