| Sunday, July 9 |
| 6:00 p.m. |
Dinner |
| Evening Session |
Scott Denmark, Univ. Of IL, Discussion Leader |
| 7:20 - 7:30 p.m. |
Greeting by GRC Chair and Staff |
| 7:30 - 8:10 |
Brad Henke, Glaxo Wellcome
The Design and Synthesis of the Novel PPARg Agonist GI 262570 |
| 8:10 - 8:25 |
Discussion |
| 8:25 - 9:20 |
Marvin Miller, Univ. of Notre Dame
Molecular Diversity from Acylnitroso Diels-Alder Chemistry |
| 9:20 - |
Discussion |
| 9:40 - |
Welcome Reception and Mixer |
| Monday, July 10 |
| 7:30 - 8:30 a.m |
Breakfast |
| Morning Session |
Karen Romines, Glaxo Wellcome, Discussion Leader |
| 8:30 - 9:00 a.m. |
Photograph |
| 9:00 - 9:50 |
Jeff Aubé, Univ. of Kansas
The Conversion of Alkyl Azides into Heterocycles |
| 9:50 - 10:05 |
Discussion |
| 10:05 - 10:45 |
Margaret Chu-Moyer and Jerry Murry, Pfizer and Merck
Discovery and Process Research Toward a Potent Inhibitor of Sorbitol Dehydrogenase |
| 10:45 - 11:00 |
Discussion |
| 11:00 - 11:15 |
Break |
| 11:15 - 12:05 p.m. |
Keith Woerpel, Univ. of CA at Irvine
New Methods for Stereoselective Synthesis Based Upon the Reactions of Silacyclopropanes |
| 12:05 - 12:20 |
Discussion |
| 12:30 - 1:30 |
Lunch |
|
Poster Session # 1 |
| 6:00 |
Dinner |
| Evening Session |
George O'Doherty, University of Minnesota, Discussion Leader |
| 7:30 - 8:00 p.m. |
Paul Hanson, Univ. of Kansas
Metathesis Approaches to Diverse Phosphorus- and Sulfur-Based Motifs |
| 8:00 - 8:10 |
Discussion |
| 8:10 - 8:30 |
George O'Doherty, University of Minnesota
C-Arylglycoside Natural Products via an Enantioselective Dihydroxylation of Vinylfurans |
|
Discussion |
| 8:40 - 9:35 |
Tohru Fukuyama, Univ. of Tokyo
Synthetic Studies on Heterocyclic Natural Products |
| 9:35 - |
Discussion |
| Tuesday, July 11 |
| 7:30 a.m. |
Breakfast |
| Morning Session |
Susan Sobolov, Pfizer, Discussion Leader |
| 8:30 - 9:20 a.m. |
Wolfgang Steglich, Univ. of Munich
Biomimetic Syntheses of Alkaloids from Toadstools and Marine Organisms |
| 9:20 - 9:35 |
Discussion |
| 9:35 - 10:05 |
Jim Audia, Eli Lilly
Synthesis of Lactams: Heterocycles of Interest to a Medicinal Chemist |
| 10:05 - 10:15 |
Discussion |
| 10:15 - 10:45 |
Break, Meeting of GRC Het. Chairs - Past, Present and Future |
| 10:45 - 11:15 |
Amy Howell, Univ. of Connecticut
The synthesis and Utility of some unusual, strained heterocycles |
| 11:15 - 11:25 |
Discussion |
| 11:25 - 12:05 |
David Gin, Univ. of IL.
New Methods for Carbohydrate Synthesis |
| 12:05 - 12:25 |
Discussion |
| 12:30 |
Lunch |
| 6:00 |
Dinner |
| Evening Session |
William Murray, RW Johnson Research Institute, Discussion Leader |
| 7:30 - 8:00 p.m. |
Sandy Mills, Merck
Heterocyclic antagonists of the CCR5 receptor as novel anti-HIV-1 agents |
| 8:00 - 8:10 |
Discussion |
| 8:10 - 8:30 |
Richard Hsung, University of Minnesota
A tandem Knoenenagel condensation-electrocyclic ring closure strategy for constructing piperidinyl heterocycles |
| 8:30 - 8:40 |
Discussion |
| 8:40 - 9:35 |
Jeffrey Winkler, Univ. of PA
Synthesis of Natural and Unnatural Products |
| 9:35 - |
Discussion |
| Wednesday, July 12 |
| 7:30 a.m. |
Breakfast |
| Morning Session |
Carl Lovely, University of Texas at Arlington, Discussion Leader |
| 8:30 - 9:10 a.m. |
Rob Hoffman, New Mexico State Univ.
New Methods for Synthesis of Densely Functionlized Compounds |
| 9:15 - 9:30 |
Discussion |
| 9:30 - 10:00 |
Marisa Kozlowski, Univ. of PA
Design, Synthesis, and Application of Novel Cis-Decalin Type Chiral Ligands |
| 10:00 - 10:10 |
Discussion |
| 10:10 - 10:30 |
Break |
| 10:30 - 10:40 |
Nominations for Chair for 2002 |
| 10:40 - 11:10 |
Roland Dolle, Pharmacopia
Heterocyclic Scaffolds in Combinatorial Chemistry
|
| 11:10 - 11:20 |
Discussion |
| 11:20 - 12:10 |
Ross Kelly, Boston College
Design and Synthesis of Some Molecular Devices |
| 12:10 - 12:25 |
Discussion |
| 12:30 |
Lunch |
|
Poster Session # 2 |
| 6:00 |
Dinner |
| Evening Session |
Nancy Totah, University of Iowa, Discussion Leader |
| 7:30 - 8:00 p.m. |
William Lubell, Univ. of Montreal
Scope and Limitations of N-Phenylfluorenyl cyclic Sulfamidates as Electrophiles in the Synthesis of Glutamate Receptor Ligands and Azacycloalkane Amino Acids. |
| 8:00 - 8:10 |
Discussion |
| 8:10 - 8:30 |
Carl Lovely, University of Texas at Arlington
Novel approaches to the functionalization of Imidazoles |
| 8:30 - 8:40 |
Discussion |
| 8:40 - 9:35 |
Steve Martin, Univ. of Texas
A General Strategy for the Synthesis of C-Aryl Glycoside Antibiotics |
| 9:35 - |
Discussion |
| Thursday, July 13 |
| 7:30 a.m. |
Breakfast |
| Morning Session |
John Gupton, University of Richmond, Discussion Leader |
| 9:00 - 9:50 a.m. |
Yves Langlois, Université de Paris-sud
Recent Progress in Asymmetric Cycloadditions |
| 9:50 - 10:05 |
Discussion |
| 10:05 - 10:35 |
David Barnes, Abbott
Catalytic, Asymmetric Addition of 1,3-Dicarbonyl Compounds to Nitroalkenes |
| 10:35 - 10:45 |
Discussion |
| 10:45 - 11:00 |
Election of Chair |
| 11:25 - 12:15 |
John Wood, Yale University
Recent Progress in the Synthesis of Several Welwitindolinones |
| 12:15 - 12:30 |
Discussion |
| 12:30 |
Lunch |
|
Chairman’s Reception & Wine Tasting |
| 6:00 |
Banquet |
| Evening Session |
Lou Jungheim, Eli Lilly, Discussion Leader |
| 7:30 - 8:30 p.m. |
Paul Anderson, Dupont Pharm.
Heterocyclic Compounds in Drug Discovery |
| 8:30 - 8:45 |
Discussion |
| 8:45 - |
Scott Denmark: Vice Chairman's Remarks |
| Friday, July 14 |
| 7:00 - 9:00 am |
Breakfast |
| 9:00 |
Bus Departs for Logan Airport, Boston |
