The GRC on Heterocyclic Compounds is one of the longest running Gordon Research Conferences, which reflects the vitality and importance of the subject matter. The field of heterocyclic organic chemistry provides the strategies and chemical reactions that enable the preparation of structurally complex, heterocycle-containing natural products, new pharmaceutical agents, and organic materials. The continued evolution of this field is crucial to achieving efficient, cost-effective solutions to increasingly complex problems in organic synthesis and to accessing unexplored structural space. Through formal research lectures from outstanding scientists, poster sessions and informal discussions, this conference presents an excellent opportunity to any scientist who is interested in gaining knowledge of the most recent advances in the field.