Sunday 
 
 
2:00 pm - 9:00 pm 
	
Arrival and Check-in
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 7:40 pm 
	
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
 
 
						
7:40 pm - 9:30 pm 
	
The Connectivity Between Methodology Development and Total Synthesis 
 
 
 
						
7:40 pm - 7:50 pm 
	
Opening Remarks
 
 
						
7:50 pm - 8:30 pm 
	
"From Synthesis to Therapeutic Application: Making Heterocycles Great Again" 
 
 
 
						
8:30 pm - 8:40 pm 
	
Discussion
 
 
						
8:40 pm - 9:20 pm 
	
"Photocatalytic Oxidation Reactions" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Monday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 12:30 pm 
	
Improvements to the Synthesis of Heterocyclic Compounds 
 
 
 
						
9:00 am - 9:35 am 
	
"Sulfamate Esters Guide Atom-Transfer Processes" 
 
 
 
						
9:35 am - 9:45 am 
	
Discussion
 
 
						
9:45 am - 10:00 am 
	
"N-Doped Carbon-Supported Cobalt Nanoparticle Catalysis for Oxidation Reactions Based on Polymer Incarceration Methods" 
 
 
 
						
10:00 am - 10:10 am 
	
Discussion
 
 
						
10:10 am - 10:40 am 
	
Coffee Break
 
 
						
10:40 am - 11:10 am 
	
"Chemoselective, Stereocontrolled Cu-Catalyzed C-N Couplings Towards a Highly Potent mPI3Ka Inhibitor" 
 
 
 
						
11:10 am - 11:20 am 
	
Discussion
 
 
						
11:20 am - 12:00 pm 
	
"Bioactive Natural Products and New Reactions to Prepare Them: The Symbiotic Loop" 
 
 
 
						
12:00 pm - 12:10 pm 
	
Discussion
 
 
						
12:10 pm - 12:30 pm 
	
Poster Previews
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
Unique Applications of Heterocycles to Broad Biology Challenges 
 
 
 
						
7:30 pm - 8:05 pm 
	
"Discovery and Development of PET Tracers for Neuroscience" 
 
 
 
						
8:05 pm - 8:15 pm 
	
Discussion
 
 
						
8:15 pm - 8:35 pm 
	
"Tryptophan-Derived Probes for Studying the Kynurenine Pathway" 
 
 
 
						
8:35 pm - 8:45 pm 
	
Discussion
 
 
						
8:45 pm - 9:20 pm 
	
"Roles of CDK8/19 in Oncology" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Tuesday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
8:30 am - 9:00 am 
	
Group Photo
 
 
						
9:00 am - 12:30 pm 
	
Development of Methodology for Improved Heterocyclic Synthesis 
 
 
 
						
9:00 am - 9:30 am 
	
"C-H and C-O Functionalization via Radical Chaperones" 
 
 
 
						
9:30 am - 9:40 am 
	
Discussion
 
 
						
9:40 am - 10:10 am 
	
"Discovery and Synthesis of Triazolopyridines as Potent and Selective AMPAR γ8-TARP Negative Modulators" 
 
 
 
						
10:10 am - 10:20 am 
	
Discussion
 
 
						
10:20 am - 10:50 am 
	
Coffee Break
 
 
						
10:50 am - 11:20 am 
	
"An Electrocatalytic Approach to New Reaction Discovery" 
 
 
 
						
11:20 am - 11:30 am 
	
Discussion
 
 
						
11:30 am - 12:00 pm 
	
"Synthesis of Highly Functionalized N-Alkyl 2-Pyridones and Indolizines" 
 
 
 
						
12:00 pm - 12:10 pm 
	
Discussion
 
 
						
12:10 pm - 12:30 pm 
	
Poster Previews
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
The Use of Novel Approaches to the Synthesis of Biologically Active Compounds 
 
 
 
						
7:30 pm - 8:05 pm 
	
"Exploratory Process Development of a Second Generation Beta-Amyloid Cleaving Enzyme (BACE1) Inhibitor" 
 
 
 
						
8:05 pm - 8:15 pm 
	
Discussion
 
 
						
8:15 pm - 8:35 pm 
	
"Discovery and Optimization of Novel Dopamine Receptor Modulators for the Treatment of CNS Disorders" 
 
 
 
						
8:35 pm - 8:40 pm 
	
Discussion
 
 
						
8:40 pm - 9:20 pm 
	
"Synthesis of a Highly Functionalized Octahydro-Isoindole-Based NK1 Receptor Antagonist" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Wednesday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 12:30 pm 
	
Heterocycles and Their Use as Biological Probes 
 
 
 
						
9:00 am - 9:30 am 
	
"New Reactions of Indole for Enabling Synthesis and Biology" 
 
 
 
						
9:30 am - 9:40 am 
	
Discussion
 
 
						
9:40 am - 10:10 am 
	
"Reaction Cascades for Heterocycle Synthesis" 
 
 
 
						
10:10 am - 10:20 am 
	
Discussion
 
 
						
10:20 am - 10:50 am 
	
Coffee Break
 
 
						
10:50 am - 11:20 am 
	
"Natural Product Synthesis" 
 
 
 
						
11:20 am - 11:30 am 
	
Discussion
 
 
						
11:30 am - 12:05 pm 
	
"Total Synthesis of Complex Natural Products" 
 
 
 
						
12:05 pm - 12:15 pm 
	
Discussion
 
 
						
12:15 pm - 12:30 pm 
	
Poster Previews
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:00 pm - 7:30 pm 
	
Business Meeting 
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair 
 
 
						
7:30 pm - 9:30 pm 
	
The Use of Heterocycles in Catalysis 
 
 
 
						
7:30 pm - 8:05 pm 
	
"Heterocycle Synthesis for the Treatment of Pain, Cystic Fibrosis and Hepatitis C" 
 
 
 
						
8:05 pm - 8:15 pm 
	
Discussion
 
 
						
8:15 pm - 8:35 pm 
	
"Leveraging Metal Carbenes for Assembling Complexity" 
 
 
 
						
8:35 pm - 8:40 pm 
	
Discussion
 
 
						
8:40 pm - 9:20 pm 
	
"Redox Catalysis Strategies for Complex Molecules" 
 
 
 
						
9:20 pm - 9:30 pm 
	
Discussion
 
 
						
	Thursday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am - 12:30 pm 
	
New Strategies for the Synthesis of Heterocycles 
 
 
 
						
9:00 am - 9:35 am 
	
 
 
						
9:35 am - 9:45 am 
	
Discussion
 
 
						
9:45 am - 10:20 am 
	
"Deciphering the Gut Microbiota with Chemistry" 
 
 
 
						
10:20 am - 10:30 am 
	
Discussion
 
 
						
10:30 am - 11:00 am 
	
Coffee Break
 
 
						
11:00 am - 11:35 am 
	
"Discovery and Synthesis of PF-6821497, a Potent EZH2 Inhibitor" 
 
 
 
						
11:35 am - 11:45 am 
	
Discussion
 
 
						
11:45 am - 12:20 pm 
	
"New Synthetic Opportunities with Alkenyl Nitrones and Hydroxylamines" 
 
 
 
						
12:20 pm - 12:30 pm 
	
Discussion
 
 
						
12:30 pm - 1:30 pm 
	
Lunch
 
 
						
1:30 pm - 4:00 pm 
	
Free Time
 
 
						
4:00 pm - 6:00 pm 
	
Poster Session 
 
 
						
6:00 pm - 7:00 pm 
	
Dinner
 
 
						
7:30 pm - 9:30 pm 
	
Keynote Session: Nature Inspired Synthesis of Heterocyclic Natural Products 
 
 
 
						
7:30 pm - 8:15 pm 
	
"Translational Chemistry" 
 
 
 
						
8:15 pm - 8:25 pm 
	
Discussion
 
 
						
8:25 pm - 9:10 pm 
	
"Inspired by Molecular Structure and the Challenge of Doing Chemistry on Strong C-H Bonds" 
 
 
 
						
9:10 pm - 9:20 pm 
	
Discussion
 
 
						
9:20 pm - 9:30 pm 
	
Closing Remarks
 
 
						
	Friday 
 
 
7:30 am - 8:30 am 
	
Breakfast
 
 
						
9:00 am 
	
Departure