Saturday
1:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
3:45 pm - 4:30 pm
Keynote Session: Fostering a Growth Mindset as a Trainee, Building Resilience and Adaptability in Science and Medicine
3:45 pm - 3:50 pm
Introduction by Discussion Leader
3:50 pm - 4:20 pm
"Fostering a Growth Mindset: Investing in Yourself as an Early Career Scientist"
4:20 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Revolutionizing Cancer Research Through Paradigm-Shifting Insights in Hormone Receptor Biology
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm - 7:45 pm
"Identification of Nuclear Factors that Influence Estrogen Receptor Alpha Binding and Effects on Estrogen-Mediated Gene Expression"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
"Temporal Tracking of Epigenetic Plasticity after Glucocorticoid Receptor Stimulation Identifies Early and Late Responses in ER+ Breast Cancer"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:20 pm
"The Evolving Complexity of TRβ-Mediated Tumor Suppression"
8:20 pm - 8:25 pm
Discussion
8:25 pm - 8:40 pm
"FOXA2 Alters the AR Cistrome and Remodels the Chromatin Landscape to Promote the Transition to Neuroendocrine Prostate Cancer"
8:40 pm - 8:45 pm
Discussion
8:45 pm - 8:55 pm
"IGFBP3-Mediated SphK1/S1P Signaling Drives Enzalutamide Resistance in Advanced Prostate Cancer: Targeting This Axis to Overcome Therapy Resistance"
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:15 pm
"Exploring FOXA1 and the Role of Repressors in ER+ Breast Cancer Metastasis"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Innovative Translational Strategies for Hormone-Dependent Cancers: Discovery and Clinical Applications
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:15 am
"Understanding CDK4/6 Inhibitor Resistance Mechanisms in ER+ Breast Cancer"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
"The WinPro trial: A Window-of-Opportunity Trial of Preoperative Endocrine Therapy With and Without Micronized Progesterone in ER+/PR+/HER2- Early Breast Cancer"
9:35 am - 9:40 am
Discussion
9:40 am - 9:50 am
"Retinoic Acid Signaling Governs Neuroendocrine Prostate Cancer Heterogeneity"
9:50 am - 9:55 am
Discussion
9:55 am - 10:10 am
"Interplay Between PRC2 and DNA Methyltransferases Mediates Prostate Cancer Lineage Plasticity"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
"Opposing Immune Circuits Govern Natural Killer Cell Fate and Function in Prostate Cancer"
10:25 am - 10:30 am
Discussion
10:30 am - 10:45 am
"Dissecting the Impact and Spatial Heterogeneity of Endocrine Signalling in the Bone Metastatic Niche"
10:45 am - 10:50 am
Discussion
10:50 am - 11:00 am
General Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Mentorship Component: Building Your Translational Research Toolkit Through Essential Skills, Networking and Collaboration
1:30 pm - 1:35 pm
Introduction by Discussion Leader
1:35 pm - 2:30 pm
Panel Discussion
Building Your Translational Research Toolkit Through Essential Skills, Networking and Collaboration
2:30 pm - 3:00 pm
Evaluation Period
Complete the GRS Evaluation Forms; Election of Future Chair(s)
3:00 pm
Seminar Concludes