Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Foundational Pathways in Immune Cell Metabolism
7:40 pm - 8:15 pm
"Metabolic Reprogramming and Engineering of Cancer Immunity: Mitochondria Take Center Stage"
8:15 pm - 8:30 pm
Discussion
8:30 pm - 9:05 pm
"Distinct Control of T Cell Proliferation and Effector Function by Partitioning of Intracellular Sulfur from Cysteine"
9:05 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Nutrient Utilization and Immune Cell Specialization
9:00 am - 9:20 am
"T Cell Immunometabolism Across Scales"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Proteostasis in T cells"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Modeling the Microenvironment: Hot Mitochondria and Inflammation"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Mitochondrial One-Carbon Metabolism Tunes T Cell Fate During Infection"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Rejuvenating Immune Responses"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Lipid Metabolism and Immune Modulation
7:30 pm - 7:50 pm
"Lipid Metabolism at the Host-Pathogen Interface"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"A Shift in Dietary Fat Quality Improves Pulmonary Inflammation Through the Production of Oxygenated Lipid Mediators"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Lipid-Based Control of Anti-Tumor Immunity"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Short Talk Selected from Poster Abstracts
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Obesity, Nutritional Cues, and Immune Regulation
9:00 am - 9:20 am
"Microbial Derived Metabolites Boost Anti-Tumor Immunity in Obesity-Associated Cancer"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Reversing the Metabolic, Immunosuppressive and Procancer Effects of Obesity: A Mechanistic Comparison of Dietary, Surgical and Pharmacological Weight Loss Interventions"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Immunometabolic Functions of Tissue Resident Macrophages"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Immune Cell Dysregulation in Metabolic Dysfunction Associated Steatohepatitis"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Selective mRNA Translation Drives Adipose Tissue Remodeling"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Adaptive Immunity and Tumor Metabolism
7:30 pm - 7:50 pm
"Built for Extremes: T Cell Resilience to Environmental Stress"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Role of Cholesterol Metabolism in Tumor-mediated Dendritic Cell Dysfunction and Immunotherapy Resistance"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Metabolic Control of T Cell Checkpoint Function"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Short Talk Selected from Poster Abstracts
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Myeloid Cell Metabolism and Inflammation
9:00 am - 9:20 am
"Metabolic Control of Monocytes"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Type I Interferon Dysregulates the Tissue-Resident Macrophage Landscape"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Microbiome-Host Interactions Mediate Immunotherapy Responsiveness in Triple-Negative Breast Cancer"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Metabolic Regulation of Myeloid Cell Fate and IL-1 Signaling in Atherosclerosis"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"How Mitochondria Control Cytokines"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Aging, Immunosenescence, and Cognitive Decline
7:30 pm - 7:50 pm
"Immunometabolic Regulation of Antibody Responses in Aging and Age-Assocaited Conditions"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Cellular Metabolism and Healthy Brain Aging"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"The Role of B Cells in T Cell Immunosenescence"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Short Talk Selected from Poster Abstracts
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
ER Stress, Inflammatory Signaling, and Systemic Disease
9:00 am - 9:20 am
"Organelle Architecture and Function as a Novel Homeostatic Mechanism"
9:20 am - 9:30 am
Discussion
9:30 am - 9:50 am
"Feeding Immunity: Dietary Fatty Acids Dictate Dendritic Cell Fitness and Function"
9:50 am - 10:00 am
Discussion
10:00 am - 10:20 am
"Immunometabolism in Systemic Autoimmunity"
10:20 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:20 am
"Notching Up Another One During Efferocytosis"
11:20 am - 11:30 am
Discussion
11:30 am - 11:50 am
"Sensing DNA as a Danger Signal through the cGAS-STING Pathway"
11:50 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Host-Pathogen and Environmental Interactions
7:30 pm - 7:50 pm
"Nutritional Control of Infection Defense"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"Chimeric IL-6 Family Ligands: New Opportunities to Treat Diseases Related to Gut-Liver Crosstalk"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Metabolic Pathways that Divide Pathogenic and Non-Pathogenic Th17 Cells"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:10 pm
Short Talk Selected from Poster Abstracts
9:10 pm - 9:15 pm
Discussion
9:15 pm - 9:25 pm
Short Talk Selected from Poster Abstracts
9:25 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure