The 2022 Gordon Conference on Ligand Recognition and Molecular Gating will address the molecular mechanisms and physiological roles of three important classes of membrane proteins: ion channels, transporters and G-protein coupled receptors. These proteins play key roles in physiology, their malfunction is implicated in a large number of neuromuscular, endocrine, cardiac and metabolic disorders and therefore are major pharmacological targets. This year, the Conference will integrate the cryoEM-fueled explosion in understanding the structural bases of function of these proteins, with an expanded elucidation of their roles in human physiology and their exploitation as drug targets.
The Conference, makes an explicit effort to encourage young scientists to present their work and to discuss with more established investigators. All participants are asked to submit abstracts and bring posters, from which we will select additional speakers for short talks. A Gordon Research Seminar (GRS) will precede the GRC and will provide young scientists with expanded opportunities to present their work and to meet experienced scientists in an informal setting. We strongly encourage graduate students and post-doctoral fellows to apply to the GRS and to stay for the GRC. We would also like to invite scientists from industry, as the membrane proteins discussed at this GRC/GRS are major drug targets. We strongly encourage minorities and people with disabilities to apply. We are trying to secure funding to support in part those with financial constraints.
The conference will consist of nine sessions, on the topics listed below. The conference chair is currently developing their preliminary program, which will include the names of the invited speakers and discussion leaders for each of these sessions. Please check back regularly for updates to this information.
- Integrating Structures in Physiology
- Mechanisms of Gating
- Novel Approaches to Investigate Membrane Protein Structure and Function
- Structural Insights in Membrane Protein Function
- Pathophysiology of Membrane Transport and Signaling
- Protein-Membrane Interactions
- Structural Pharmacology
- Structural Dynamics
- Late-Breaking Topics