Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Keynote Session: Lymphatic Vessels in Neglected Diseases
Discussion Leaders: Kerstin Wilhelm-Jüngling (Max Planck Institute for Heart and Lung Research, Germany) and Malou van Zanten (St George's, University of London, United Kingdom)
3:45 pm - 4:15 pm
Michael Dellinger (University of Texas Southwestern Medical Center, USA)
"Vanishing Act: Lymphatic Vessels and Disappearing Bones"
4:15 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
The Lymphatic System and Its Role in Human Diseases
Discussion Leaders: Jennifer Frattolin (Imperial College London, United Kingdom) and Silvia Martin-Almedina (St George's, University of London, United Kingdom)
7:30 pm - 7:45 pm
William Repicci (Lymphatic Education & Research Network, USA)
"The Activism-Progress Nexus of Lymphatic Research"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Dionysios Grigoriadis (St George's, University of London, United Kingdom) and Ege Ozkan Sackey (St. George's University of London, United Kingdom)
"Genotyping in a Population-Based Study Identifies a Genetic Association with Lipedema"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Rafael Czepielewski (Washington University School of Medicine, USA)
"Mesenteric Lymphatic Collecting Vessel Obstruction by Tertiary Lymphoid Organs Is Associated with Disrupted Valves and Is a Feature of Murine Inflammatory Bowel Disease"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Rahul Ravindran (University of Oxford, United Kingdom)
"Exploring the Lymphatic System in the Persistence and Resolution of Intestinal Inflammation"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Natalie Nielsen (University of North Carolina at Chapel Hill, USA)
"Cardiac Lymphatics Resolve Myocardial Edema in Increased Coronary Sinus Pressure Model"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Jingna Xue (University of Calgary, Canada)
"Skin Inflammation Impairs Neutrophil Response to Staphylococcus aureus Infection via the Compromised Lymph Flow"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Healthy Lymphatics: Development, Structure and Function
Discussion Leaders: Nils Hansmeier (Charité - Universitaetsmedizin Berlin, Germany) and Sinem Karaman (Wihuri Research Institute / University of Helsinki, Finland)
9:00 am - 9:10 am
Magda Hernandez (Uppsala University, Sweden)
"Identification of a New Transcriptional Regulator of Collecting Lymphatic Vessel Morphogenesis"
9:10 am - 9:15 am
Discussion
9:15 am - 9:25 am
Janette Kazenwadel (University of South Australia, Australia)
"Lymphatic Endothelial Cell Identity Is Controlled by a GATA2 Bound Enhancer"
9:25 am - 9:30 am
Discussion
9:30 am - 9:40 am
Emilia Korhonen (University of Helsinki / Wihuri Research Institute, Finland)
"Angiopoietin-Tie Signaling in Postnatal Lymphatic Vessel Development"
9:40 am - 9:45 am
Discussion
9:45 am - 9:55 am
Xu Peng (Texas A&M University, USA)
"Deletion of Zonula Occludens-1 (Zo-1) in Vascular Endothelial Cells Causes Embryonic Lethality with Lymphatic Vessel Dilation"
9:55 am - 10:00 am
Discussion
10:00 am - 10:10 am
Pedro Vallecillo Garcia (Freie Universität Berlin, Germany)
"Osr1 Orchestrates Lymph Node Initiation and Vasculature Formation During Embryogenesis"
10:10 am - 10:15 am
Discussion
10:15 am - 10:25 am
Yang Lee (Boston Children's Hospital / Harvard Medical School, USA)
"Loss of Lymphatic Endothelial Foxc2 in Adult Mice Protects Against Diet-Induced Obesity by Promoting Lymphangiogenesis and Lacteal Junction Integrity"
10:25 am - 10:30 am
Discussion
10:30 am - 10:40 am
Anna Oszmiana (Centre for Cancer Biology, University of South Australia, Australia)
"FAT4 Plays a Role in the Establishment of Cell Polarity in Lymphatic Endothelial Cells by Regulating the Organization of Actin Cytoskeleton"
10:40 am - 10:45 am
Discussion
10:45 am - 10:55 am
Simon Stritt (Uppsala University, Sweden)
"Integrin αvβ3 Signaling Regulates Developmental Lymphangiogenesis in Mice"
10:55 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Interdisciplinary Approaches to Lymphatic Research
Discussion Leaders: Anish Mukherjee (Georgia Institute of Technology, USA) and Wenjing Xu (University of North Carolina at Chapel Hill, USA)
1:30 pm - 1:40 pm
Thu Hoang (Monash University, Australia)
"A Novel Cervical Lymph Cannulation Method in Rats to Evaluate the Lymphatic Clearance of Therapeutics from the Brain"
1:40 pm - 1:45 pm
Discussion
1:45 pm - 1:55 pm
Dimitrios Kalogiros (Centre for Mathematical Medicine and Biology, University of Nottingham, United Kingdom)
"Combining In Vitro Data and Mathematical Models to Characterize Chemokine Gradient Development in Lymphatic Interstitium"
1:55 pm - 2:00 pm
Discussion
2:00 pm - 2:10 pm
Daniel Watson (Imperial College London, United Kingdom)
"Volumetric Imagining in Upper Limb Breast Cancer Related Lymphoedema Offers Insights Beyond Volume Measurement"
2:10 pm - 2:15 pm
Discussion
2:15 pm - 2:25 pm
Kevin Campbell (University of California, Davis, USA)
"Designing Endothelial Progenitor Cell Based Strategies to Promote Lymphangiogenesis"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes
