Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Autophagy and Organelle Quality Control
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:10 pm
"Regulation of Mitophagy and Cellular Bioenergetics During Hypoxia"
8:10 pm - 8:20 pm
Discussion
8:20 pm - 8:40 pm
"Molecular Mechanisms of Selective Autophagy"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:00 pm
Short Talk Selected from Poster Abstracts
9:00 pm - 9:05 pm
Discussion
9:05 pm - 9:15 pm
Short Talk Selected from Poster Abstracts
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Lysosome Stress Resilience and Growth Control
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"The Lysosome in Nutrient Sensing and Cellular Growth Control"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
"Lysosomal Quality Control in Health and Disease"
10:00 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 11:00 am
"Mechanisms of Mechanoresilience in Lysosomes"
11:00 am - 11:10 am
Discussion
11:10 am - 11:30 am
"Cellular Responses to Lysosomal Membrane Damage"
11:30 am - 11:40 am
Discussion
11:40 am - 11:50 am
Short Talk Selected from Poster Abstracts
11:50 am - 11:55 am
Discussion
11:55 am - 12:05 pm
Short Talk Selected from Poster Abstracts
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:20 pm
Late-Breaking Topic
12:20 pm - 12:25 pm
Discussion
12:25 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Membrane Scaffolds and Endo/Exo-Lysosomal Pathways
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 8:00 pm
"Fundamental Role of CD63 and its Harnessing to Study the Endo/Exo-Lysosomal Pathway"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:30 pm
"Novel Biomarkers of Endolysosomal Function in Health and Disease"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:00 pm
"Caveolin-1 Scaffolds in Caveolae Mechanosignaling"
9:00 pm - 9:10 pm
Discussion
9:10 pm - 9:20 pm
Short Talk Selected from Poster Abstracts
9:20 pm - 9:25 pm
Discussion
9:25 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Endolysosomes and Organelle Crosstalks
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"At the Crossroads: Membrane Contact Site Crosstalk in Cholesterol Homeostasis"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
"Retromer in Age-Related Neurodegenerative Disease"
10:00 am - 10:10 am
Discussion
10:10 am - 10:45 am
Coffee Break
10:45 am - 11:05 am
"Endosome: ER Crosstalk During Autophagosome Biogenesis"
11:05 am - 11:15 am
Discussion
11:15 am - 11:25 am
Late-Breaking Topic
11:25 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:25 pm
Short Talk Selected from Poster Abstracts
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Lysosomes as Engines of Cellular Change
7:30 pm - 7:50 pm
"Uncovering Lysosome Mediated Adaptative Mechanisms During Cancer Metastasis"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"How do Lysosomes Shape Cell Identity? Using Synthetic Biology to Untangle the Role of Organelle Partitioning During Asymmetric Cell Division in Fate Specification"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"A Pigmented View of the Primary Cilium"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Imagining the Future of Cell Biology and Cell Biologists"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Imaging and Quantitative Endo-Lysosomal Biology
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Intravital Microscopy to Investigate Actomyosin Regulation of Membrane Remodeling in Endo-Lysosome Biology"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
"Leveraging Fluorogen-Activated Bimolecular Complementation to Detect and Induce Organelle Interactions"
10:00 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 10:55 am
Late-Breaking Topic
10:55 am - 11:05 am
Discussion
11:05 am - 11:15 am
Short Talk Selected from Poster Abstracts
11:15 am - 11:20 am
Discussion
11:20 am - 11:30 am
Short Talk Selected from Poster Abstracts
11:30 am - 11:35 am
Discussion
11:35 am - 11:45 am
Short Talk Selected from Poster Abstracts
11:45 am - 11:50 am
Discussion
11:50 am - 12:10 pm
"Lysosome Biology by Combining cryoET, Fluorescence Microscopy and Spatial Proteomics"
12:10 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Dynamics of Endosomal Function
7:30 pm - 7:50 pm
"The Retrograde Transport Machinery as a Shared Vulnerability in Viral Infections"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 8:20 pm
"From Yeast to Humans: Insights into the Dynamic Regulation of Signaling Lipids on Endosomes"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
"Endosomal Trafficking of Immune Checkpoint Receptors"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
"Endosomal Trafficking in Metabolic Control and Diabetes"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Endo-Lysosomes in Ageing and Neurodegeneration
9:00 am - 9:10 am
Introduction by Discussion Leader
9:10 am - 9:30 am
"Cellular Mechanisms of Ageing and Ocular Disease"
9:30 am - 9:40 am
Discussion
9:40 am - 10:00 am
"Endolysosomal Membrane Damage and Repair in Neurodegeneration"
10:00 am - 10:10 am
Discussion
10:10 am - 10:40 am
Coffee Break
10:40 am - 10:55 am
Late-Breaking Topic
10:55 am - 11:05 am
Discussion
11:05 am - 11:15 am
Short Talk Selected from Poster Abstracts
11:15 am - 11:20 am
Discussion
11:20 am - 11:30 am
Short Talk Selected from Poster Abstracts
11:30 am - 11:35 am
Discussion
11:35 am - 11:45 am
Short Talk Selected from Poster Abstracts
11:45 am - 11:50 am
Discussion
11:50 am - 12:10 pm
"Role of BMP Dysregulation in Neurodegenerative Diseases"
12:10 pm - 12:20 pm
Discussion
12:20 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Keynote Session: Lysosomes, Related Organelles and their Specific Functions
7:30 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 9:10 pm
"Lysosomal Curiosities: Armed with Granules, Primed for Destruction, and Hungry for Targets"
9:10 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure