|
| Afternoon | Arrival and registration |
| 6:00 p.m. | Dinner |
| 7:20 pm | Introductory remarks (Chris Newbold) |
| 7:30-9:30 p.m. | Population Biology |
|
| Discussion leader Prof Dan Hartl |
| 7:30-7:40 | Introduction Prof Dan Hartl |
| 7:40-8:05 | Sarah Volkman
Recent Origin of Plasmodium falciparum from a Single Progenitor--Implications for Genomic Approaches to Identify Drug Resistance Determinants in Malaria |
| 8:05-8:15 | Discussion |
| 8:15-8:40 | Karen Day |
| 8:40-8:50 | Discussion |
| 8:50-9:15 | David Conway
Natural Selection on Plasmodium falciparum - some beautiful ramifications?' |
| 9:15-9:35 | Discussion + general discussion |
|
| 9:00am | Exploiting the genome |
|
| Discussion leader Prof Alan Cowman |
| 9:00-9:30 | Alan Cowman
Analysis of function and trafficking of proteins involved in cytoadherence of P.falciparum infected erythrocytes |
| 9:30-9:45 | Discussion |
| 9:45-10:15 | Dan Carucci
Proteomic Analysis of P. falciparum |
| 10:15-10:30 | Discussion |
| 10:30-11:00 | Coffee |
| 11:00-11:30 | Andy Waters
The use of genetic manipulation to investigate Plasmodium berghei gamete fertilisation and parasite development in the mosquito vector. |
| 11:30-11:45 | Discussion |
| 11:45-12:15 | David Roos
PlasmoDB: Mining the Plasmodium Genome Database |
| 12:15-12:30 | Discussion |
| 12:30 | Lunch |
| 1:30-4:30 | Free time |
| 4:30-6:00 | Poster Session |
| 6:00 p.m. | Dinner |
| 7:30-9:30 p.m. | Protein Trafficking |
|
| Discussion leader: Klaus Lingelbach |
| 7:30-7:55 | Klaus Lingelbach
Signal sequences and mediator molecules required for protein secretion in Plasmodium falciparum |
| 7:55-8:10 | Discussion |
| 8:10-8:35 | Kasturi Haldar
Rafts and apicomplexan infection |
| 8:35-8:50 | Discussion |
| 8:50-9:15 | Keith Joiner
A comparison of endocytic targeting in T. gondii and P. falciparum |
| 9:15-9:30 | Discussion |
|
|
| Discussion leader :Tom Wellems |
| 9:00-9:45 | Tom Wellems
Determinants of chloroquine resistance in falciparum and vivax malaria |
| 9:45-10:00 | Discussion |
| 10:00-10:45 | Steve Ward |
| 10:45-11:00 | Discussion |
| 11:00-11:30 | Coffee |
| 11:30-12:15 | Chris Plowe
Update on molecular markers for drug-resistant malaria: Implementation and insight into clinical immunity |
| 12:15-12:30 | Discussion |
| 12:30 | Lunch |
| 1:30-4:30 | Free time |
| 4:30-6:00 | Poster Session |
| 6:00 p.m. | Dinner |
| 7:30-9:30 p.m. | Antigenic variation |
|
| Discussion leader: Artur Scherf |
| 7:30-7:55 | Artur Scherf
A central role for P. falciparum nuclear architecture in antigenic variation |
| 7:55-8:10 | Discussion |
| 8:10-8:35 | Peter Presier
Stage specific expression of the 235 kDa rhoptry protein in Plasmodium yoelii |
| 8:35-8:50 | Discussion |
| 8:50-9:15 | Kirk Dietsch
The role of var introns in gene silencing and activation |
| 9:15-9:30 | Discussion |
|
|
| Discussion leader: Dominic Kwiatkowski |
| 9:00-9:30 | Dominic Kwiatkowski
Mapping malaria susceptibility genes |
| 9:30-9:45 | Discussion |
| 9:45-10:15 | Terrie Taylor
Clinicopathological correlates of fatal malaria: timing is everything |
| 10:15-10:30 | Discussion |
| 10:30-11:00 | Coffee |
| 11:00-11:30 | Mats Wahlgren
Role of PfEMP1 in the Pathogenicity Mechanisms of Severe Malaria |
| 11:30-11:45 | Discussion |
| 11:45-12:15 | Patrick Duffy
Malaria pathogenesis during pregnancy |
| 12:15-12:30 | Discussion |
| 12:30 | Lunch |
| 1:30-4:30 | Free time |
| 4:30-6:00 | Poster Session |
| 6:00 p.m. | Dinner |
|
| Discussion leader: Chetan Chitnis |
| 7:30-8:15 | Chetan Chitnis
DBL domains and red cell invasion by malaria parasites |
| 8:15-8:30 | Discussion |
| 8:30-9:15 | Tony Holder
Merozoite surface proteins, antibodies and red blood cell invasion |
| 9:15-9:30 | Discussion |
|
|
| Discussion leader: Jean Langhorne |
| 9:00-9:30 | Jean Langhorne |
| 9:30-9:45 | Discussion |
| 9:45-10:15 | Magda Plebanski
'Immuno-suppression, malaria and vaccine development'. |
| 10:15-10:30 | Discussion |
| 10:30-11:00 | Coffee |
| 11:00-11:30 | Britta Urban
Plasmodium falciparum: infected erythrocytes alter the phenotype of dendritic cells in vitro and in vivo |
| 11:30-11:45 | Discussion |
| 11:45-12:15 | Fidel Zavala
Induction and activation of CD8+ T cells against liver stages: A swift and tightly regulated process. |
| 12:15-12:30 | Discussion |
| 12:30 | Lunch |
| 1:30-4:30 | Free time |
| 4:30-6:00 | Poster Session |
| 6:00 p.m. | Dinner |
|
| Discussion leader: Steve Hoffman |
| 7:30-7:55 | Steve Hoffman
Rationale, progress and prospects for a multi-stage prime boost malaria vaccine |
| 7:55-8:10 | Discussion |
| 8:10-8:35 | Pierre Druilhe |
| 8:35-8:50 | Discussion |
| 8:50-9:15 | Adrian Hill
Effector T-cell vaccines for malaria |
| 9:15-9:30 | Discussion |
