Sunday |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Environmental Impacts upon Reproduction and
Offspring Health |
| Discussion Leader: Amander Clark (University of California, Los Angeles, USA) |
7:40 pm - 7:50 pm | Introduction by Discussion Leader |
7:50 pm - 8:15 pm | Patricia Hunt (Washington State University, USA) "The Perils of Making Gametes in the 21st Century" |
8:15 pm - 8:25 pm | Discussion |
8:25 pm - 8:50 pm | Jodi Flaws (University of Illinois, USA) "Environmental Chemicals and the Female Reproductive System" |
8:50 pm - 8:55 pm | Discussion |
8:55 pm - 9:20 pm | Douglas Kwon (Massachusetts Institute of Technology / Harvard University, USA) "The Role
of Genital Inflammation and the Vaginal Microbiome in HIV Acquisition Risk" |
9:20 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Genetic Regulation of Reproductive Outcomes |
| Discussion Leader: Margaret (Peggy) Petroff (Michigan State University, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Kjersti Aagaard (Baylor College of Medicine, USA) "Unexpected
Beginnings: How the Intrauterine and Maternal Microbial and Metabolic Environments
Influence Offspring Health" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Alex Bortvin (Carnegie Institution for Science, USA) "Sex-Specific
Strategies and Outcomes of Transposon Control in Germ Cells" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:30 am | Wenfeng An (South Dakota State University, USA) "The Missing Link Between Retrotransposon Activation and Meiotic Failure in piRNA-Deficient Mice" |
10:30 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Group Photo / Coffee Break |
11:05 am - 11:15 am | Kathryn Grive (Cornell University, USA) "TAF4b Regulates Oocyte-Specific Genes Essential for Meiosis and Primordial Follicle Development" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:30 am | Hieu Nguyen (University of Hawaii at Manoa, USA) "A New Found Function of the DNA Licensing Protein ORC4 on Polar Body Extrusion" |
11:30 am - 11:35 am | Discussion |
11:35 am - 12:00 pm | Monika Ward (University of Hawaii, USA) "To Be or
Not to Be: Essential and Not So Essential Roles of Mouse Y Chromosome Genes in
Germline Regulation" |
12:00 pm - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Sylvia Hewitt (National Institute of Environmental Health Sciences, NIH, USA) "Negative Elongation Factor Subunit B (NELF-B) Is Essential for Endometrial Function" |
12:20 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Editing the Genes of Gametes and Embryos |
| Discussion Leader: Francesco Demayo (National Institute of Environmental Health Sciences, NIH, USA) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:05 pm | John Schimenti (Cornell University, USA) "Genetic Variation and Human Fertility" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | F. Kent Hamra (Universtity of Texas Southwestern Medical Center, USA) "Integrating
Genome Editing Technologies into Robust Rattus norvegicus Spermatogenesis
Colony Forming Assays" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Randall Prather (University of Missouri-Columbia, USA) "Editing the Pig Genome for Agriculture and Biomedicine" |
9:15 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | General Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Epigenetic Regulation in Reproduction |
| Discussion Leader: John McCarrey (University of Texas at San Antonio, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Marisa Bartolomei (University of Pennsylvannia, USA) "Regulation of Genomic Imprinting in
Development and Disease" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Myriam Hemberger (Babraham Institute, United Kingdom) "Epigenetic and Transcriptional Networks Controlling Trophoblast Stem
Cells – The Stepping Stone for Normal Placentation and Reproductive Health" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:30 am | Felipe Vilella (Fundación IVI / INCLIVA, Spain) "Maternal Endometrial Hsa-miR-30d Is Necessary for Embryo Implantation" |
10:30 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:15 am | Steen Ooi (University College London, United Kingdom) "A Novel Role for Microprocessor Component Drosha in Cytosine Methylation" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:30 am | Qi Chen (University of Nevada, Reno School of Medicine, USA) "Sperm tsRNAs and RNA Modifications in Diet-Induced Epigenetic Inheritance" |
11:30 am - 11:35 am | Discussion |
11:35 am - 12:00 pm | Sue Hammoud (University of Michigan Medical School, USA) "Chromatin Dynamics and Its Role in Developing Germ Cells" |
12:00 pm - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Christopher Payne (Feinberg School of Medicine, Northwestern University, USA) "Dicer1-Mediated Silencing of INSM1 in Spermatogonia Permits the Expression of PHD Finger Protein 1 and Global Polycomb Group Methyltransferase Activity" |
12:20 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Stem Cells in Reproduction |
| Discussion Leader: Wei Yan (University of Nevada School of Medicine, USA) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:05 pm | Jan Brosens (University of Warwick, United Kingdom) "Endometrial Stem Cell Deficiency and Recurrent Pregnancy Loss" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Brian Hermann (University of Texas at San Antonio, USA) "Defining the Mammalian Spermatogonial Stem Cell Pool" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Harry Leitch (MRC Clinical Sciences Centre, Medical Research Council, United Kingdom) "Nanog, Pluripotency and the Germline Revisited" |
9:15 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | General Discussion |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Bioengineering and Reproductive Health |
| Discussion Leader: Kyle Orwig (University of Pittsburgh, USA) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Daniela Ulrich (Medical University of Graz, Austria) "Bioengineering
of the Lower Female Reproductive Tract - New Approaches for Treating Pelvic
Organ Prolapse" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Mats Hellstrom (University of Gothenburg, Sweden) "Uterus Transplantation Followed by Bioengineering of the Uterus" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:30 am | Yasushi Hirota (The University of Tokyo, Japan) "STAT3 Promotes Uterine Regeneration in a Mouse Model of Decellularized Uterine Matrix Transplantation" |
10:30 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:15 am | Chris Geyer (East Carolina University, USA) "Retinoid Catabolism Regulates Spermatogonial Fate in the Mouse Testis" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:30 am | Enrique Sosa (University of California, Los Angeles, USA) "Developing a Non-Human Primate Model for Stem Cell and Germline Research" |
11:30 am - 11:35 am | Discussion |
11:35 am - 12:00 pm | Joanna Burdette (University of Illinois at Chicago, USA) "Engineering
the Female Reproductive Tract Using Microfluidics" |
12:00 pm - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Ripla Arora (University of California, San Francisco, USA) "Imaging the Implanting Embryo and the Uterine Environment in Three-Dimensions" |
12:20 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Reproductive Transcription and Signaling Pathways |
| Discussion Leader: Diana Laird (University of California, San Francisco, USA) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:05 pm | Blanche Capel (Duke University, USA) "Committing to Testis or Ovary Fate" |
8:05 pm - 8:15 pm | Discussion |
8:15 pm - 8:40 pm | Shuangbo Kong (State Key Laboratory of Stem Cell and Reproductive Biology, China) "Molecular Determinants of Uterine Receptivity" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:15 pm | Aleksandar Rajkovic (University of Pittsburgh, USA) "Reproductive Aging and
Overall Health: Is There a Link?" |
9:15 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | General Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Continuing Challenges to Human Reproductive
Health |
| Discussion Leader: Xiujun Fan (Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, China) |
9:00 am - 9:10 am | Introduction by Discussion Leader |
9:10 am - 9:35 am | Jacquetta Trasler (McGill University, Canada) "Epigenetic Targets of
Environmental and Drug Exposures in Germ Cells and Embryos" |
9:35 am - 9:45 am | Discussion |
9:45 am - 10:10 am | Michal Neeman (Weizmann Institute of Science, Israel) "Recent Developments in MRI Analysis of Maternal Angiogenesis During Early
Pregnancy in Mice" |
10:10 am - 10:20 am | Discussion |
10:20 am - 10:30 am | Ernesto Figueiro-Filho (Federal University of Mato Grosso do Sul, Brazil) "White Matter Diffusion Tensor Imaging (DTI) and Resting State Functional Connectivity (rs-fMRI) Differ in Children Born from Preeclamptic Gestations" |
10:30 am - 10:35 am | Discussion |
10:35 am - 11:05 am | Coffee Break |
11:05 am - 11:15 am | Melissa Pepling (Syracuse University, USA) "Oocyte Survival and Follicle Formation in an Estrogen Deficient Environment" |
11:15 am - 11:20 am | Discussion |
11:20 am - 11:30 am | Nava Dekel (Weizmann Institute of Science, Israel) "Hyaluronic Acid: Anti-Angiogenic Shield for the Post-Implantation Embryo" |
11:30 am - 11:35 am | Discussion |
11:35 am - 12:00 pm | Andrew Sharkey (University of Cambridge, United Kingdom) "HLA-KIR Associations in Human Reproductive Success" |
12:00 pm - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Gunter Wagner (Yale University, USA) "The Role of Inflammation in the Evolution of Mammalian Pregnancy" |
12:20 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 5:30 pm | Poster Session |
5:30 pm - 7:30 pm | Keynote Session: Milestones in Reproductive
Biology |
| Discussion Leaders: Jon Oatley (Washington State University, USA) and Humphrey Yao (National Institute of Environmental Health Sciences, NIH, USA) |
5:30 pm - 5:40 pm | Introduction by Discussion Leader |
5:40 pm - 6:10 pm | Mitch Eddy (National Institute of Environmental Health Sciences, NIH, USA) "The Ark of Life: The Germ
Line - Past, Present and Future" |
6:10 pm - 6:25 pm | Discussion |
6:25 pm - 6:35 pm | Introduction by Discussion Leader |
6:35 pm - 7:05 pm | Marilyn Renfree (University of Melbourne, Australia) "Reproduction
Down Under: The 6% Solution" |
7:05 pm - 7:20 pm | Discussion |
7:20 pm - 7:25 pm | General Discussion |
7:25 pm - 7:30 pm | Closing Remarks |
8:00 pm | Dinner |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |