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Mammary Gland Biology (GRS)

Gordon Research Seminar

Cellular Signaling and the Environment in Mammary Gland Development in Disease

June 8 - 9, 2019

Chairs Alison Obr and Chelsea M. Lassiter

Contact Chairs

Jordan Hotel at Sunday River

27 Grand Circle

Newry, ME, US

Venue and Travel Information

Conference Description

The Gordon Research Seminar on Mammary Gland Biology is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

The primary focus of this meeting is on cutting-edge research in mammary gland development and disease, bringing together young investigators active in these research areas. The goal is to encourage discussion that connects the fundamental processes during mammary gland development with alterations that occur during tumorigenesis.

This meeting will also include a special mentoring session to advise graduate students and post-docs on how make a successful career transition.

Related Meeting

This GRS will be held in conjunction with the "Mammary Gland Biology" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
2:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm	Epithelial-Stromal Interactions in the Mammary Gland and Disease Discussion Leader: Michelle Williams (University of Colorado Anschutz Medical Campus, USA)
3:45 pm - 3:55 pm	Maria Cristina Miranda Vergara (University of Notre Dame, USA) "Stromal Matrix Metalloproteinase 3 (MMP3) Regulates Immune Cell Recruitment to Inhibit Primary Tumor Burden in Breast Cancer"
3:55 pm - 4:00 pm	Discussion
4:00 pm - 4:10 pm	Vasudha Srivastava (University of California, San Francisco, USA) "Physical Mechanisms for Oncogene-Induced Breakdown in Mammary Tissue Structure"
4:10 pm - 4:15 pm	Discussion
4:15 pm - 4:25 pm	Sarah Tarullo (University of Colorado Anschutz Medical Campus, USA) "Matrix Remodeling by Semaphorin 7a Promotes Invasion in Postpartum Breast Cancer"
4:25 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Cancer Stem Cells and Tumorigenesis/Mammary Gland Development Discussion Leader: Jessica Elswood (Texas A&M University, USA)
7:30 pm - 7:45 pm	Thu Truong (University of Minnesota, USA) "Steroid Receptor Co-Activators PELP1 and SRC-3 Cooperate to Drive Luminal Breast Cancer Stemness"
7:45 pm - 7:50 pm	Discussion
7:50 pm - 8:05 pm	Olivia McGinn (University of Colorado Anschutz Medical Campus, USA) "CK5 and β-Catenin Interact to Promote Breast Cancer Stem Cell Properties"
8:05 pm - 8:10 pm	Discussion
8:10 pm - 8:25 pm	Sirinapa Sribenja (Roswell Park Comprehensive Cancer Center, USA) "Foxa1 Deletion in Mouse Mammary Gland Increases Proportion of Luminal Progenitor Cells: A Link to Racial Disparity in Breast Cancer"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 8:45 pm	Cole McQueen (Texas A&M University, USA) "PER2 Regulation of Mammary Gland Development"
8:45 pm - 8:50 pm	Discussion
8:50 pm - 9:05 pm	Gillian Wilson (University of Glasgow, United Kingdom) "CCR1 Is an Important Regulator of Branching Morphogenesis in the Mammary Gland"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:25 pm	Haris Girish (Baylor College of Medicine, USA) "The Intestinal Microbiome of High and Low-Lactation Capacity Inbred Mice Changes with Strain and Is Shaped by Pregnancy and Lactation"
9:25 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Immune Microenvironment Regulation in Mammary Gland Biology Discussion Leader: Emily Irey (University of Minnesota, USA)
9:00 am - 9:15 am	Garhett Wyatt (Texas A&M University, USA) "Cross-Talk Between SIM2s and NFkB Regulates Cyclooxygenase 2 Expression in Breast Cancer"
9:15 am - 9:20 am	Discussion
9:20 am - 9:35 am	Danielle Renner (University of Minnesota, USA) "Macrophage Contributions to Mammary Tumor Metastasis"
9:35 am - 9:40 am	Discussion
9:40 am - 9:55 am	Katelyn Kozma (SickKids, Canada) "Defining the Role of Stat3 Signaling in the Metastatic Dissemination"
9:55 am - 10:00 am	Discussion
10:00 am - 10:15 am	Michelle Williams (University of Colorado Anschutz Medical Campus, USA) "Reversal of an Epithelial to Mesenchymal Program by miR-200c Reveals a Pro-Metastatic Cytokine Profile in Triple Negative Breast Cancer"
10:15 am - 10:20 am	Discussion
10:20 am - 10:35 am	Genevra Kuziel (University of Wisconsin-Madison, USA) "Inflammation-Induced CD11b+ Cells Contribute to Mammary Tumor Fibrosis"
10:35 am - 10:40 am	Discussion
10:40 am - 10:55 am	Manjusha Ghosh (University of Regensburg, Germany) "Identification of Metastatic Founder Cells by Single Cell Phylogenies"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Career Panel Discussion Leader: Teresa Monkkonen (University of California, San Francisco, USA)
1:30 pm - 2:30 pm	Panel Discussion Designing a Game Plan for the Next Step in Your Career Michael Lewis (Baylor College of Medicine, USA) Traci Lyons (University of Colorado Anschutz Medical Campus, USA) Jerrica Breindel (Quinnipiac University, USA)
2:30 pm - 3:00 pm	Evaluation Period Fill in GRS Evaluation Forms
3:00 pm	Seminar Concludes

Contributors

Funding for this conference was made possible (in part) by 1R13CA239577-01 from the National Cancer Institute and National Institute of Environmental Health Sciences. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

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Conference History Mammary Gland Biology

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Mammary Gland Biology

June 7 - 12, 2020

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