Sunday |
4:00 pm - 8:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:30 pm | Genetically Encoded Small Molecules from Marine
Organisms |
| Discussion Leader: Shigeki Matsunaga (The University of Tokyo, Japan) |
7:40 pm - 8:00 pm | Opening Remarks: Introduction by the GRC
Chairs and a Brief Recap of the GRS by the GRS Chairs |
8:00 pm - 8:40 pm | Bradley Moore (Scripps Institution of Oceanography, USA) "Biosynthetic
Gene Clusters - Nature's Gift to Discovery and Application" |
8:40 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Tal Luzzatto-Knaan (University of California, San Diego, USA) "Chemodiversity Based Cartography of Natural Products from Marine Communities" |
9:20 pm - 9:30 pm | Discussion |
Monday |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | Synthetic Biology of Natural Products |
| Discussion Leader: Mohamed Donia (Princeton University, USA) |
9:00 am - 9:30 am | Emily Balskus (Harvard University, USA) "Chemical Discovery in the Microbial World" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:15 am | Eric Schmidt (University of Utah, USA) "Novel Neuroactive Marine Natural Products" |
10:15 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:10 am | Selected from Poster Abstracts: Jason Kwan (University of Wisconsin-Madison, USA) "Using Shotgun Metagenomics to Investigate Natural Products from Uncultured Bacteria in Marine Invertebrates" |
11:10 am - 11:15 am | Discussion |
11:15 am - 11:25 am | Selected from Poster Abstracts: Xinyu Liu (University of Pittsburgh, USA) "An Emerging View of Hapalindole-Type Alkaloid Biogenesis" |
11:25 am - 11:30 am | Discussion |
11:30 am - 12:10 pm | Sarah O'Connor (John Innes Centre, United Kingdom) "Understanding How Nature Makes Nitrogen-Containing Natural Products: Elucidating and Engineering Alkaloid Pathways from Plants" |
12:10 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Molecular Targets and Omics Approaches |
| Discussion Leader: Roberto Berlinck (University of Sao Paulo, Brazil) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:20 pm | Leticia Costa-Lotufo (University of Sao Paulo, Brazil) "Prospecting Anticancer Compounds on the Brazilian Coast: From Simple to Complex and Back" |
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Carole Bewley (National Institute of Diabetes and Digestive and Kidney Diseases, NIH, USA) "Anti-Infectives from Nature: Identifying Targets and Elucidating Mechanisms" |
9:15 pm - 9:30 pm | Discussion |
Tuesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Organismal Interactions in Wet and Not-so-Wet Worlds |
| Discussion Leader: Amy Lane (University of North Florida, USA) |
9:00 am - 9:30 am | Toshiyuki Wakimoto (Hokkaido University, Japan) "Activated Chemical Defense of a Sponge-Microbe Association" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:15 am | Danielle Dixson (University of Delaware, USA) "The Importance of Including Chemically Mediated Behavior in Creating Effective Marine Management" |
10:15 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:10 am | Selected from Poster Abstracts: Jessie Ochoa (University of California, Santa Cruz, USA) "Phylogenetic and Metabolomic Analysis Contributes to Emerging Spirotetronate Polyketides" |
11:10 am - 11:15 am | Discussion |
11:15 am - 11:25 am | Selected from Poster Abstracts: Kristen Whalen (Woods Hole Oceanographic Institution, USA) "Louder than Words: Bacterial Cell Signals Are Drivers of Algal Lysis" |
11:25 am - 11:30 am | Discussion |
11:30 am - 12:10 pm | Martin Kaltenpoth (Johannes Gutenberg University of Mainz, Germany) "Evolution and Chemical Ecology of Defensive Microbial Symbioses in Insects" |
12:10 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Antibiotic Discovery and Microbial Secondary Metabolism |
| Discussion Leader: Brian Murphy (University of Illinois at Chicago, USA) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:20 pm | Mohammad Seyedsayamdost (Princeton University, USA) "Unveiling the Hidden Secondary Metabolomes of Bacteria" |
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Stefan Schulz (Technische Universität Braunschweig, Germany) "Volatiles from Marine Bacteria" |
9:15 pm - 9:30 pm | Discussion |
Wednesday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Creative Chemical Solutions to Mysterious Molecules |
| Discussion Leader: Tim Bugni (University of Wisconsin-Madison, USA) |
9:00 am - 9:30 am | Tadeusz Molinski (University of California, San Diego, USA) "Integrated Approaches for Discovery of Bioactive Natural Products from Marine Invertebrates" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:15 am | Richmond Sarpong (University of California, Berkeley, USA) "New Strategies and Methods for the Synthesis of Marine Alkaloids" |
10:15 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:10 am | Selected from Poster Abstracts: Thomas Williamson (Merck & Co. Inc., USA) "Small Molecule Structure Characterization: New and Improved NMR Methods" |
11:10 am - 11:15 am | Discussion |
11:15 am - 11:25 am | Selected from Poster Abstracts: Danmeng Luo (University of Florida, USA) "Total Synthesis of the Potent Marine-Derived Elastase Inhibitor Lynbyastatin 7 and In Vitro Biological Evaluation in Model Systems for Pulmonary Diseases" |
11:25 am - 11:30 am | Discussion |
11:30 am - 12:10 pm | Kirk Gustafson (National Cancer Institute, NIH, USA) "Interesting New Structures and How We Can Solve Them: Application of Contemporary Structural Elucidation Techniques" |
12:10 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair |
7:30 pm - 9:30 pm | Microbial Signaling in a Vast Ocean |
| Discussion Leader: David Rowley (University of Rhode Island, USA) |
7:30 pm - 7:40 pm | Introduction by Discussion Leader |
7:40 pm - 8:20 pm | Tracy Mincer (Woods Hole Oceanographic Institution, USA) "Listening in on Microbial Natural Product Production Under Perturbation: Towards Understanding Global Cellular Production of Secondary Metabolites" |
8:20 pm - 8:35 pm | Discussion |
8:35 pm - 9:15 pm | Georg Pohnert (Friedrich-Schiller-Universität Jena, Germany) "Gradients and Events: The Chemistry of Plankton Interactions" |
9:15 pm - 9:30 pm | Discussion |
Thursday |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Targeting Human Disease with Natural Products |
| Discussion Leader: Yali Fu (National Cancer Institute, NIH, USA) |
9:00 am - 9:30 am | Anokha Ratnayake (Pfizer, USA) "The Process of Designing and Developing Natural Products-Based Antibody Drug Conjugates for the Treatment of Cancer" |
9:30 am - 9:45 am | Discussion |
9:45 am - 10:15 am | Robert Capon (University of Queensland, Australia) "Exploring Microbial Chemical Ecology as a Pathway for Accessing Silent Secondary Metabolism" |
10:15 am - 10:30 am | Discussion |
10:30 am - 11:00 am | Coffee Break |
11:00 am - 11:10 am | Selected from Poster Abstracts: Samantha Mascuch (Georgia Institute of Technology, USA) "Mechanism of Action of the Cyanobacterial Marine Natural Product Honaucin A" |
11:10 am - 11:15 am | Discussion |
11:15 am - 11:25 am | Selected from Poster Abstracts: James Anson (Royal Society of Chemistry, United Kingdom) "Marine Natural Products Review Article: A New Look for 2016" |
11:25 am - 11:30 am | Discussion |
11:30 am - 12:10 pm | John MacMillan (University of Texas Southwestern Medical Center, USA) "Microbial Natural Products with Selective Activity Against Non-Small Cell Lung Cancer" |
12:10 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Keynote Session: Development of Marine Natural Products as
Pharmaceuticals and Tools for Research |
| Discussion Leader: Paul Jensen (Scripps Institution of Oceanography, USA) |
7:30 pm - 7:45 pm | Opening Remarks |
7:45 pm - 8:15 pm | Eduardo Esquenazi (Sirenas Marine Discovery, USA) "A Small Company's Perspective on Opportunities
for Marine Inspired Drug Discovery and Development in Today's Pharma Environment" |
8:15 pm - 8:30 pm | Discussion |
8:30 pm - 9:10 pm | Ronald Quinn (Griffith University, Australia) "Towards the Bedside: The Journey from 10 kg
Marine Organism and Animal Screening to Molecular Targets to Patient-Derived
Cells" |
9:10 pm - 9:30 pm | Discussion |
Friday |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |