|Sunday, June 14, 7:30 pm
I. Meiosis and Gametogenesis in Multicellular Eukaryotes
Discussion Leader: Steve Wasserman, Univ. of Texas, Southwestern Medical
- Stephanie Sherman, Emory University
"Non-disjunction in humans: a tale of twenty-ones"
- David Page, Whitehead Institute and MIT
"Human infertility, germ cell development, and the Y chromosome"
- Gareth Jones, University of Birmingham, UK
"Hunting meiotic genes in Arabidopsis"
- Amin Ghabrial, Princeton University
"Identification of a class of genes required for patterning and meiosis during Drosophila oogenesis"
- Christopher Makaroff, Miami University (10 min.)
""Characterization of Arabipodis mutants exhibiting defects in meiosis
|Monday, June 15, 9:00 am
II. Checkpoints and the Meiotic Cell Cycle
Discussion Leader: R. Scott Hawley, University of California, Davis
- Bruce Nicklas, Duke University
"Errors in mitosis and meiosis and how to avoid them"
- Ann Rose, University of British Columbia (10 min.)
"Conservation of spindle assembly checkpoint function in C. elegans"
- Beth Rockmill, Yale University (10 min.)
"Yeast genes involved in meiotic homolog pairing"
- Tim Schedl, Washington University
"Control of meiotic prophase progression and gametogenesis in C. elegans"
- Steve Wasserman, Univ. of Texas, Southwestern Medical School
"Meiotic regulation in Drosophila males"
- Bernard Maro, Institut Jacques Monod, Université Paris VII
"Control of meiotic spindle formation in mouse oocytes"
- David Stuart, The Scripps Research Institute
"B-type cyclins are required for entry into premeiotic S-phase and activation of a meiotic S-phase checkpoint"
|Monday, June 15, 7:30 pm
III. The Meiotic Spindle and Cytokinesis
Discussion Leader: Tim Schedl, Washington University
- George Vande Woude, National Cancer Institute - Frederick Cancer Research and Development Center
"Morphogenesis of the first meiotic spindle in oocytes of Xenopus laevis"
- Patricia Hunt, Case Western Reserve
Chromosomal control of meiotic spindle formation in murine oocytes
- R. Scott Hawley, Univ. of California, Davis
"Mechanisms of meiotic spindle formation and achiasmate segregation in Drosophila females"
- Paul Straight, Univ. of Colorado (10 min.)
"Regulation of spindle pole body duplication during meiosis in yeast"
- Maurizio Gatti, University of Rome, Italy
"Genetic and molecular analysis of meiotic cytokinesis of Drosophila melanogaster males"
|Tuesday, June 16, 9:00 am
Discussion Leader: Tom Petes, University of North Carolina - Chapel Hill
- Harry Scherthan, University of Heidelberg, Germany
"Three-dimensional aspects of chromosome behavior during homology search"
- Zac Cande, University of California, Berkeley
"Meiotic prophase chromosome behavior in maize"
- Yasushi Hiraoka, Kansai Advanced Research Center, Kobe, Japan
"The role of telomere clustering in homologous chromosome pairing in fission yeast"
- Michael Dresser, Oklahoma Medical Research Foundation
"Ndj1p involvement in early meiotic recombination"
- Ed Louis, John Radcliffe Hospital, Oxford (10 min.)
"Telomere recombination in meiosis: sequestering and non-random choice of partners"
- Robin Allshire, MRC Human Genetics Unit, Edinburgh, Scotland
"Fission yeast centromere and telomeres"
|Tuesday, June 16, 7:30 pm
V. Homolog Pairing
Discussion Leader: Anne Villeneuve, Stanford University
- G. Shirleen Roeder, Yale University
"Function and assembly of the yeast synaptonemal complex and coordination with meiotic nuclear division"
- Nancy Kleckner, Harvard University
"Chromosome pairing, DNA replication and Spo11"
- Alastair Goldman, NIH (10 min.)
"Allelic recombination and telomeres both play a role in the process of meiotic chromosome pairing"
- Dawn Thompson, University of Oregon (10 min.)
"Genetic control of recombination partner preference in yeast meiosis"
- Terry Ashley, Yale University School of Medicine
"Mammalian meiotic synapsis and recombination: the same or separate phenomenon"
- Peter Moens, York University, Toronto, Canada
"Focus on foci"
|Wednesday, June 17, 9:00 am
VI. Chromosome Condensation and Cohesion
Discussion Leader: G. Shirleen Roeder, Yale University
- Doug Koshland, Carnegie Institution of Washington
"Genetically challenged meiosis; or in other words, mitosis"
- Barbara Meyer, University of California, Berkeley
"Connections between meiosis, mitosis and dosage compensation in C. elegans"
- Terry Orr-Weaver, Whitehead Institute and MIT
"The centromere protein MEI-S332 maintains cohesion in meiosis and mitosis"
- Wayne Wahls, Vanderbilt University
"A pathway of chromatid cohesion and centromere proximal recombination required for meiotic chromosome segregation in fission yeast"
- Jose Suja, University of Madrid, Spain
"Implication of phosphorylated proteins in sister chromatid cohesion during meiotic divisions"
- Majorie Maguire, University of Texas
"Sister chromatid cohesiveness in maize"
|Wednesday, June 17, 7:30 pm
VII. Initiation of Double-Strand Breaks
Discussion Leader: James Haber, Brandeis University
- James Wang, Harvard University
"DNA topoisomerases: an update"
- Anne Villeneuve, Stanford University School of Medicine
"Differential reliance on conserved recombination pathways"
- Kim McKim, Rutgers University (10 min.)
"The initiation of meiotic recombination in Drosophila melanogasterrequires a homolog of the spo11 gene"
- Alain Nicolas, CNRS, Université Paris-Sud, France
"Control of double-strand break formation on the chromosome III and minisatellite rearrangement in the yeast S. cerevisiae"
- Tom Petes, University of North Carolina
"Meiotic recombination hotspots and coldspots in S. cerevisiae"
- Gerry Smith, Fred Hutchinson Cancer Research Center
"Control of meiotic recombination in S. pombe"
|Thursday, June 18, 9:00 am
VIII. Business Meeting/Recombination Complexes
Discussion Leader: Alain Nicolas, Institute Curie, France
- Steve West, ICRF, UK
"DNA interactions catalyzed by the human Rad51 and Rad52 proteins"
- Doug Bishop, University of Chicago
"Assembly of recombination complexes"
- Tomoko Ogawa, National Institute of Genetics, Japan
"Roles of mre11 protein in yeast recombination"
- Jim Haber, Brandeis University
"Mechanisms of double-strand break repair in mitosis and meiosis"
- Takashi Morita, Osaka University (15 min.)
"Mouse Dmc1 gene is required for homologous synapsis of chromosomes in meiosis"
- Christa Heyting, Agricultural University, Wageningen, The Netherlands
"Localization of Rad50 and Mre11 proteins within spermatocytes of the mouse"
|Thursday, June 18, 7:30 pm
IX. Regulation of Meiosis
Discussion Leader: Michael Lichten, National Institutes of Health
- Masayuki Yamamoto, University of Tokyo, Japan
"RNA-assisted nuclear transport of the meiotic regulator in fission yeast"
- Aaron Mitchell, College of Physicians and Surgeons, Columbia Univ
"Unique and overlapping functions of yeast glycogen synthase kinase-3 homologs in meiotic transcriptional regulation"
- Rochelle Esposito, University of Chicago
"Regulation of meiosis-specific gene expression"
- Yona Kassir, Technicon, Haifa, Israel (10 min.)
""The RAS/cAPK pathway transmits a glucose signal that inhibits the transcription of IME1, the major transcriptional activator of meiosis in the budding yeast Saccharomyces cerevisiae
- Joanne Engebrecht, SUNY - Stony Brook (10 min.)
"Events during meiotic DNA replication influences homologous chromosome interactions"
- Nancy Hollingsworth, SUNY - Stony Brook
"Phosphorylation regulates interaction between two key axial element components during meiosis in yeast"
- Shelley Chu, University of California - San Francisco
"Transcriptional activation of B-type cyclins and spore formation genes at the prophase to metaphase I transcription by Ndt80"