Sunday
4:00 pm - 8:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Metals and Biological Signalling
7:40 pm - 8:20 pm
"Selective Sensing of Nitric Oxide in Biology"
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
"Zinc Receptors, Fluxes and Switches in Control of Cell Fate Decisions"
9:15 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Metal Ion Homostasis, Proteins and Nucleic Acids
9:00 am - 9:30 am
"Platinum Interactions Across the Cell: New Players and Pathways"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
"Regulation of Mn Metabolism in Bacteria: From a Small RNA to a Small Protein to Riboswitches"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
"What Are Those Fe-S Clusters Doing in Genome Maintenance Proteins?"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
"Structural Mechanisms of Transition Metal Homeostasis in Bacteria"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Metal Ion Regulation and Human Health
7:30 pm - 8:00 pm
"Iron and Ferroptosis in Brain Disease"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"New Functions of Molybdenum Enzymes in Neurodegeneration and Nitric Oxide Synthesis"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"Selective Degradation of an Extracellular Electron Shuttle Abrogates Biofilm Development"
9:20 pm - 9:30 pm
Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Global Chemical Cycles: Nitrogen
9:00 am - 9:30 am
"Synthetic Single-Site Fe N2 ases"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
"From FeMoco to FeVco: Heterometal Contributions to Nitrogenase Reactivity"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
"Towards Understanding How Metal Ions Cooperate to Activate Dinitrogen"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
"Light-Driven N2 Reduction Catalyzed by a CdS-Nitrogenase MoFe Protein Hybrid"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Global Chemical Cycles: Energy
7:30 pm - 8:00 pm
"New Insights into Hydrogenase Catalysis"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Functional Models of Mono-[Fe] Hydrogenase Using an Anthracene-Based Ligand Scaffold"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"High Spin Metal Ions as Spin Labels for Structural Studies of Proteins In-Vitro and In-Cell"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Metalloenzymes: Mechanisms and Models
9:00 am - 9:30 am
"Mechanistic Study for the Stereo-Selective Hydroxylation of [2-2 H1 ,3-2 H1 ]Butanes Catalyzed by Cytochrome P450 BM3 Variants"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
"Emerging Diversity in the Chemistry of Non-Heme Diiron Oxidases and Oxygenases"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
"Lipoxygenase: An Enzyme for All Seasons"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
"New Insights into the Mechanism of Electron Bifurcating NADH-Dependent Reduced Ferredoxin:NADP Oxidoreductase"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pm
Metals and the Environment, from the Deep Past to Today
7:30 pm - 8:00 pm
"Biological Wet Adhesion to Mineral Surfaces: Mussels, Siderophores and the Catechol-Cation Synergy"
8:00 pm - 8:10 pm
Discussion
8:10 pm - 8:40 pm
"Nickel-Driven Methanogenic Burst Accompanying Earth's Greatest Extinction"
8:40 pm - 8:50 pm
Discussion
8:50 pm - 9:20 pm
"How Bacteria Use a Multicopper Oxidase to Close the Environmental Mn Cycle by Producing MnO2 Biomineral"
9:20 pm - 9:30 pm
Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Water Oxidation/Oxygen Evolution
9:00 am - 9:30 am
"A Geobiological Perspective on the Role of Mn in the Evolution of Photosynthesis"
9:30 am - 9:45 am
Discussion
9:45 am - 10:15 am
"Studies of Oxomanganese Complexes for Natural and Artificial Photosynthesis"
10:15 am - 10:30 am
Discussion
10:30 am - 11:00 am
Coffee Break
11:00 am - 11:30 am
"High-Field Pulse EPR - A Biophysical Toolbox for the Study of the Oxygen Evolving Complex"
11:30 am - 11:45 am
Discussion
11:45 am - 12:15 pm
"New Insights into the Water Splitting Mechanism of Photosystem II by Time-Resolved Femtosecond Nanocrystallography"
12:15 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Oxygen, Life in the Balance
7:30 pm - 7:40 pm
"Directed Evolution of Cytochrome c for Carbon-Silicon Bond Formation: Bringing Silicon to Life"
7:40 pm - 7:45 pm
Discussion
7:45 pm - 7:55 pm
"Cytochrome P460: A 'New' Leak in the Biogeochemical Nitrogen Cycle"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:10 pm
"Unraveling the Mn/Fe Lipid-Binding Oxidases: An Investigation of Metal Specificity and Cofactor Assembly in R2lox"
8:10 pm - 8:15 pm
Discussion
8:15 pm - 9:15 pm
9:15 pm - 9:30 pm
Discussion
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure