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Microbiome Editing

Gordon Research Conference

A New Path Forward - Exploring the Potential of Microbiome Editing

January 11 - 16, 2026

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GRC Education Requirements: Undergraduates or those who have not obtained a bachelor's degree in science/engineering (or acceptable equivalent) are not eligible to apply to attend Gordon Research Conferences or Seminars.

Chairs

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Vice Chairs

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Sheraton Fairplex Hotel & Conference Center

601 West McKinley Ave.

Pomona, California, United States

Venue and Travel Information

Application Information

The application deadline for this meeting was December 14, 2025. You may still submit an application, which may be considered by the conference chair if there is still room available.

Conference Description

The Microbiome Editing GRC is a premier, international scientific conference focused on advancing the frontiers of science through the presentation of cutting-edge and unpublished research, prioritizing time for discussion after each talk and fostering informal interactions among scientists of all career stages. The conference program includes an array of speakers and discussion leaders from institutions and organizations worldwide, concentrating on the latest developments in the field. The conference is five days long and held in a remote location to increase the sense of camaraderie and create scientific communities, with lasting collaborations and friendships. In addition to premier talks, the conference has designated time for poster sessions from individuals of all career stages, and afternoon free time and communal meals allow for informal networking opportunities with leaders in the field.

This conference will explore the power of microbiome editing for improving human health and the environment through the discussion of the fundamental research and technological advancements needed to drive impact.

Conference Program

Sunday
2:00 pm - 9:00 pm	Arrival and Check-in
6:00 pm - 7:00 pm	Dinner
7:30 pm - 7:40 pm	Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm	Microbiomes, Culture Collections, and Consortia Discussion Leader:
7:40 pm - 8:10 pm	"Constructing and Manipulating Complex Defined Communities"
8:10 pm - 8:20 pm	Discussion
8:20 pm - 8:30 pm	"Assembly of Stool-Derived Bacterial Communities Follows “Early-Bird” Resource Utilization Dynamics"
8:30 pm - 8:35 pm	Discussion
8:35 pm - 9:05 pm	"Eco-Evolutionary Mechanisms of Microbiota-Mediated Infection Protection"
9:05 pm - 9:15 pm	Discussion
9:15 pm - 9:25 pm	"In Vitro Model Communoids for the Early Life Human Microbiome"
9:25 pm - 9:30 pm	Discussion
Monday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Predicting Microbiome Collective Behavior and Editing Target Identification Discussion Leader:
9:00 am - 9:15 am	"A Toolkit for Transposon Libraries and Functional Genomics in Intestinal Bacteroidales Species"
9:15 am - 9:20 am	Discussion
9:20 am - 9:50 am	"Microbiota Control of Host Physiology"
9:50 am - 10:00 am	Discussion
10:00 am - 10:15 am	"A Social Genetic “Target Map” to Alter the Human Gut Microbiome"
10:15 am - 10:20 am	Discussion
10:20 am - 10:50 am	Coffee Break
10:50 am - 11:20 am	"Systems Ecology of the Human Microbiome: From Identifying Emergent Properties to Unraveling Novel Functions"
11:20 am - 11:30 am	Discussion
11:30 am - 11:45 am	"Ecological and Pharmacological Approaches for Modulating Microbiome Metabolism to Produce Health-Promoting Metabolites"
11:45 am - 11:50 am	Discussion
11:50 am - 12:20 pm	"Predicting Functional Behavior in Soil Microbiomes: Leveraging Omics to Guide Editing Interventions"
12:20 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	DNA Delivery to the Microbiome: Plasmids Discussion Leader:
7:30 pm - 8:00 pm	"Engineering Conjugative Plasmids for CRISPR-Cas9 Editing in the Microbiota"
8:00 pm - 8:10 pm	Discussion
8:10 pm - 8:25 pm	"In Vivo Protein and DNA Delivery to a Broad Host Range of Bacterial Conjugation Recipients"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 9:00 pm	"Plasmids Fight Back: Anti-Defense Islands Enable Efficient Conjugation"
9:00 pm - 9:10 pm	Discussion
9:10 pm - 9:25 pm	"Using Catalytic RNA in Communities to Report on Gene Transfer Host Range and to Achieve Cell-Selective Protein Expression"
9:25 pm - 9:30 pm	Discussion
Tuesday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Group Photo
9:00 am - 12:30 pm	DNA Delivery to the Microbiome: Phages Discussion Leader:
9:00 am - 9:15 am	"Phage Foundry, a Systematic Multi-Scale Phage Characterization Capability to Develop Tools to Predictively Manipulate Microbial Communities and Use as Countermeasures to Combat Bacterial Pathogens"
9:15 am - 9:20 am	Discussion
9:20 am - 9:50 am	"Phage-Based Approaches to Eliminate or Alter Bacteria Within Complex Microbial Communities"
9:50 am - 10:00 am	Discussion
10:00 am - 10:15 am	"Phage-Derived Protein Delivery for Microbiome Interactions"
10:15 am - 10:20 am	Discussion
10:20 am - 10:50 am	Coffee Break
10:50 am - 11:20 am	"Diverse CRISPR Strategies to Engineer Bacteria and Phages, In Vitro and In Situ"
11:20 am - 11:30 am	Discussion
11:30 am - 11:45 am	"Revealing the Pervasive Landscape of MGE-Host Interactions In Situ with Single-Cell Genomics"
11:45 am - 11:50 am	Discussion
11:50 am - 12:20 pm	"Engineered Phages as Precision Antimicrobials: Enhancing Efficacy Through Effector Delivery"
12:20 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Engineering Colonization Resistance and Engraftment Discussion Leader:
7:30 pm - 8:00 pm	"Mining the Microbiome for Bacterial Strains to Displace MDR Enterobacterales from the Gut"
8:00 pm - 8:10 pm	Discussion
8:10 pm - 8:25 pm	"Leveraging Plasmid Conjugation to Improve Microbiome Editing"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 9:00 pm	"Precision Elimination of Strains from the Gut Microbiome by Niche Engineering"
9:00 pm - 9:10 pm	Discussion
9:10 pm - 9:25 pm	"Self-Selecting Systems for Microbiome Editing"
9:25 pm - 9:30 pm	Discussion
Wednesday
7:30 am - 8:30 am	Breakfast
9:00 am - 12:30 pm	Genetic Tools for Microbiome Editing Discussion Leader:
9:00 am - 9:15 am	"A Platform to Quantitatively Characterize Plasmid Conjugation Using RNA Addressable Modification and Synthetic Microbial Communities"
9:15 am - 9:20 am	Discussion
9:20 am - 9:50 am	"Engineering Phage-Derived Particles for Precise Microbiome Modulation"
9:50 am - 10:00 am	Discussion
10:00 am - 10:15 am	"Bridge Recombinase Enables Massive Genomic Edits Across the Bacterial Tree of Life"
10:15 am - 10:20 am	Discussion
10:20 am - 10:50 am	Coffee Break
10:50 am - 11:20 am	"Genetic Manipulation of Non-Model Human Gut Commensals for Mechanistic Dissection of Microbe–Host Interactions"
11:20 am - 11:30 am	Discussion
11:30 am - 11:45 am	"Genome Editing of Phylogenetically Distinct Bacteria Using Portable Retron-Mediated Recombineering"
11:45 am - 11:50 am	Discussion
11:50 am - 12:20 pm	"Engineering Sensing and Skin Modulation with Skin Microbes"
12:20 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Genotype to Phenotype in the Microbiome Discussion Leader:
7:30 pm - 8:00 pm	"New Tools and Strategies for Targeted Microbiome Modulation"
8:00 pm - 8:10 pm	Discussion
8:10 pm - 8:25 pm	"Outer Membrane Vesicles Facilitate Glycan Utilization Between Human Gut Bacteria by Transmitting Intracellular Enzymes"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 9:00 pm	"Metagenomic Editing of Commensal and Pathogenic Bacteria In Vivo Using CRISPR-Associated Transposases"
9:00 pm - 9:10 pm	Discussion
9:10 pm - 9:25 pm	"Decoding E. coli's Gut Survival Strategies: A CRISPRi Approach Across Diets, Inflammatory Environment and Strains"
9:25 pm - 9:30 pm	Discussion
Thursday
7:30 am - 8:30 am	Breakfast
8:30 am - 9:00 am	Business Meeting Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm	Microbiome Interactions with Hosts and Environments Discussion Leader:
9:00 am - 9:15 am	"Surface Expression of Antitoxin on Engineered Bacteria Neutralises Genotoxic Colibactin in the Gut"
9:15 am - 9:20 am	Discussion
9:20 am - 9:50 am	"Metabolic Modeling for Microbiome Engineering"
9:50 am - 10:00 am	Discussion
10:00 am - 10:15 am	"Lactobacillus-Vectored Nanobodies Improve Broiler Productivity Under Sub-Clinical Necrotic Enteritis with Associated Microbiome and Transcriptome Changes"
10:15 am - 10:20 am	Discussion
10:20 am - 10:50 am	Coffee Break
10:50 am - 11:20 am	"Flipping the Script: Mechanisms of Phage Evasion in the Disease-Associated Gut Bacterium Eggerthella lenta"
11:20 am - 11:30 am	Discussion
11:30 am - 11:45 am	"Targeting Gut Microbiota Structure to Modulate Oral Cholera Vaccination Outcome"
11:45 am - 11:50 am	Discussion
11:50 am - 12:20 pm	"The Dynamic Selective Landscape of Human Microbiomes"
12:20 pm - 12:30 pm	Discussion
12:30 pm - 1:30 pm	Lunch
1:30 pm - 4:00 pm	Free Time
4:00 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Clinical, Environmental, and Industrial Applications Discussion Leader:
7:30 pm - 8:00 pm	"Bacterial Delivery Systems: From Pathogenesis to Therapeutics"
8:00 pm - 8:10 pm	Discussion
8:10 pm - 8:25 pm	"Development of Cutibacterium Acnes as a Chassis for Skin-Delivered Biologics"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 9:00 pm	"Metagenomic Editing of Commensal Bacteria In Vivo: From Discovery to Translational Tools"
9:00 pm - 9:10 pm	Discussion
9:10 pm - 9:25 pm	"Engineering Probiotics and Microbiota for Real-World Applications"
9:25 pm - 9:30 pm	Discussion
Friday
7:30 am - 8:30 am	Breakfast
9:00 am	Departure

Contributors

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Poster Information

Poster sessions are an integral part of the our conferences, and offer all conferees an opportunity to discuss their research.

Preparing your GRC poster

Funding Opportunities

Financial assistance is available beginning in 2026 for qualified applicants through the Carl Storm Opportunity Fellowships program. Learn more.

Registration Fees

Conferee Single Room:

$1,810.00

Conferee Shared Room:

$1,575.00

Conferee Off-Site:

$1,340.00

Guest Single Room:

$1,590.00

Guest Shared Room:

$1,355.00

Guest Off-Site:

$1,120.00

Child 4-12 yrs Shared Room:

$678.00

Child 4-12 yrs Off-Site:

$560.00

Child Under 4 yrs Shared Room:

Free

Child Under 4 yrs Off-Site:

Free

Additional Fee Info

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